REVIEW article
Front. Mater.
Sec. Biomaterials and Bio-Inspired Materials
Volume 12 - 2025 | doi: 10.3389/fmats.2025.1635502
Advances in Graphene Oxide-Based Polymeric Wound Dressings for Wound Healing
Provisionally accepted
- Shandong University of Traditional Chinese Medicine, Jinan, China
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Conventional wound dressings can only provide basic protection for wounds and have limited ability to promote wound healing. Therefore, it is of great practical significance to develop new wound dressings with antibacterial, hemostatic, wound healing promotion, and good biocompatibility. Graphene oxide (GO), as a new type of nanomaterial, has received widespread attention in the fields of tissue engineering, bioimaging, biosensing, cancer therapy, and drug delivery. Due to unique physicochemical properties and multifunctionality of GO, polymers integrated with GO have the advantages of excellent antibacterial effect, good biocompatibility, significant wound healing promotion, and intelligent response, thus becoming new wound dressing materials with great potentials. This review systematically summaries the antibacterial, hemostatic, and angiogenic effects and mechanisms of GO. Then the research progress of GO as a core material combined with polymer compounds to form GO-based polymeric wound dressings is focused, followed by an in-depth discussion on their biocompatibility. Finally, this review further prospects the future research direction of GO-based polymeric wound dressings, with a view to providing ideas for their research and application.
Keywords: graphene oxide, Wound Dressing, Antibacterial, Hemostasis, Angiogenesis
Received: 26 May 2025; Accepted: 21 Aug 2025.
Copyright: © 2025 Li, Wang, Zhang and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Hua Zhang, Shandong University of Traditional Chinese Medicine, Jinan, China
Xin Zhang, Shandong University of Traditional Chinese Medicine, Jinan, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.