Frontiers in Oncology

Original Research

Published on 08 Dec 2025

Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression

in Pharmacology of Anti-Cancer Drugs

Sei Morinaga
Qinghong Han
Kohei Mizuta
Byung Mo Kang
Michael Bouvet
Norio Yamamoto
Katsuhiro Hayashi
Hiroaki Kimura
Shinji Miwa
Kentaro Igarashi

Frontiers in Oncology

doi 10.3389/fonc.2025.1704021

368 views

Review

Published on 08 Dec 2025

Rapidly evolving therapeutic advances for classical EGFR-mutant NSCLC

in Thoracic Oncology

Kelsey Pan
Suresh S. Ramalingam

Frontiers in Oncology

doi 10.3389/fonc.2025.1732467

505 views

Original Research

Published on 08 Dec 2025

LncRNA ZFHX4-AS1 initiates an oncogenic axis involving a ZFHX4/SOX2 positive feedback loop to accelerate glioma progression

in Neuro-Oncology and Neurosurgical Oncology

Hongshan Yan
Xue Wang
Zongmao Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1687984

445 views

Review

Published on 08 Dec 2025

Molecular mechanisms and translational advances in bladder cancer: from driver genes to precision therapy

in Genitourinary Oncology

Jinjie Xiang
Yuhui Luo
Baiyu Zhang
Kunbin Ke
Hao Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1670574

372 views

Case Report

Published on 08 Dec 2025

Vitiligo associated with ribociclib therapy: a rare case report

in Breast Cancer

Zirui Wang
Yuanrui Bai
Rihan Wu
Yihui Liu
Chunhui Dong
Ling Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1669407

342 views

Original Research

Published on 08 Dec 2025

DDX49 as a novel prognostic biomarker regulates colorectal cancer cell proliferation through the TIMM44-PI3K-AKT pathway

in Gastrointestinal Cancers: Colorectal Cancer

Baoyu Huang
Zhipeng Yin
Gang Gao
Longhai Li
Miao Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1707092

266 views

Case Report

Published on 08 Dec 2025

Case Report: Successful management of high-volume paclitaxel extravasation with hyaluronidase and dry warm compresses

in Pharmacology of Anti-Cancer Drugs

Boris Dudík
Maroš Kunderlík
Bela Mriňáková
Zuzana Lukáčová
Vanda Ušáková
Ján Klimas

Frontiers in Oncology

doi 10.3389/fonc.2025.1699608

441 views

Original Research

Published on 08 Dec 2025

Prognostic value of serum free light chain abnormalities in diffuse large B-cell lymphoma

in Cancer Epidemiology and Prevention

Zhuxia Jia
Jin Li
Jie Liu
Wenmin Han
Wei Xu
Xuzhang Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1694343

306 views

Original Research

Published on 08 Dec 2025

CD58 reshapes the immunosuppressive microenvironment in gliomas through PD-L1 upregulation

in Neuro-Oncology and Neurosurgical Oncology

Siqi Gou
Pengfei Zhao
Lei Zong
Daihua Yu
Wei Liu
Weichen Zuo
Juanhong Wang
Wei Wei

Frontiers in Oncology

doi 10.3389/fonc.2025.1658467

346 views

Original Research

Published on 08 Dec 2025

A novel approach for proton therapy pencil beam scanning patient specific quality assurance using an integrated detector system and 3D dose reconstruction

in Radiation Oncology

Joseph J. Bateman
Sonia Escribano-Rodriguez
Samuel Flynn
Tony Price
Raffaella Radogna
Saad Shaikh
Harry Barnett
Connor Godden
Matthew Warren
Febian

Frontiers in Oncology

doi 10.3389/fonc.2025.1677439

747 views

Original Research

Published on 08 Dec 2025

The impact of environmental contaminants, air pollution, and social deprivation on childhood leukemia survival in California

in Pediatric Oncology

Fernando Hernandez
Eric Stewart
Libby M Morimoto
Alice Y Kang
Lena E Winestone
Catherine Metayer

Frontiers in Oncology

doi 10.3389/fonc.2025.1686115

520 views

Original Research

Published on 08 Dec 2025

A novel approach to enhance beta-sitosterol bioavailability isolated from Jurinea macrocephala (a high-altitude) plant in biodegradable chitosan against lung cancer

in Pharmacology of Anti-Cancer Drugs

Monica Sangral
Ankita Singh
Ashutosh Gupta
Madhulika Bhagat

Frontiers in Oncology

doi 10.3389/fonc.2025.1659465

429 views

Original Research

Published on 08 Dec 2025

Epidemiological profile of patients with malignant neoplasm admitted to a tertiary care center in India: a retrospective cross-sectional study

in Cancer Epidemiology and Prevention

Sourav Debnath
Pusparghya Pal
Anurag Kumar Singh
Shivang Mishra
Sumit Rajotiya
Manashi Ghosh
Prashant Nakash
Sachin Kumar
Roshni Singh
Govind Sharma

Frontiers in Oncology

doi 10.3389/fonc.2025.1636807

381 views

Original Research

Published on 08 Dec 2025

A phase Ib/II study of modakafusp alfa alone and in combination with pembrolizumab in patients with advanced or metastatic solid tumors

in Cancer Molecular Targets and Therapeutics

David Gill
Charles L. Cowey
Gregory A. Daniels
David Sommerhalder
Raghad Abdul-Karim
John M. Kirkwood
Joanna Kolodney
Inderjit Mehmi
Rachel Roberts-Thomson
James Strauss

Frontiers in Oncology

doi 10.3389/fonc.2025.1620987

679 views

Case Report

Published on 08 Dec 2025

Rapid postoperative platelet decline in a lung adenocarcinoma with sarcomatoid differentiation and concomitant JAK2 V617F mutation: a case report

in Thoracic Oncology

Luojie Deng
Xiaoping Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1722712

303 views

Original Research

Published on 08 Dec 2025

18F-PSMA-1007 versus 18F-FDG PET/CT in the detection of hepatocellular carcinoma

in Cancer Imaging and Image-directed Interventions

Xiaoli Mei
Yanpeng Li
Shasha Xu
Xiaoping Shang
Bing Cheng
Xiaobo Niu
Xiaoting Liu
Yan Liu
Xinya Cheng
Xingmin Han

Frontiers in Oncology

doi 10.3389/fonc.2025.1711398

427 views

Original Research

Accepted on 05 Dec 2025

Cardiac Substructure Dosimetry in Postoperative Breast-Conserving Radiotherapy: A Novel 8-Field IMRT Approach for Internal Mammary Node Irradiation Using MONACO

in Radiation Oncology

Ziyi Xie
Shuai Hao
Xiao Wu
Yinliang Liu
Chaoen Bao
Ruhan Zhao
Ming Liu
Xiaohui Cao

Frontiers in Oncology

170 views

Systematic Review

Accepted on 05 Dec 2025

Infection Risks Associated with Daratumumab-Containing Regimens in Multiple Myeloma: A Systematic Review and Meta-Analysis

in Hematologic Malignancies

Zengyi Huang
Xiao-Lian Liu
Ting Li
Chao-Han Luo

Frontiers in Oncology

182 views

Original Research

Accepted on 05 Dec 2025

Brachytherapy stents versus conventional plastic stents for the treatment of malignant ureteral obstruction: initial experience

in Genitourinary Oncology

Yipu Li
Chengzhi Zhang
Mengyao Song
Zhanguo Sun
Xinwei Han
Xueliang Zhou
Dechao Jiao

Frontiers in Oncology

Systematic Review

Accepted on 05 Dec 2025

Quality and Accuracy of Radiomics Models in Predicting KRAS Status in Lung Cancer: A Systematic Review and Meta-Analysis

in Thoracic Oncology

Xin Dong Luo
Ziqiang Wang
Di Lu
Yaping Wang
Wenliang Wang
Pengcheng Dong
Yunjiu Gou
Yayuan Yang

Frontiers in Oncology

100 views

Original Research

Accepted on 05 Dec 2025

Kinetic and radiomic features on DCE-MRI as a predictor for axillary lymph node metastasis burden in T1 and T2 stage breast cancer

in Breast Cancer

Yuanyuan Liu
Chunhua Wang
Ruirui Meng
Hongbing Luo
Xiaoyu Chen
Shaoyu Wang
Jing Ren
Peng Zhou
Xin Zhang

Frontiers in Oncology

217 views

Review

Accepted on 05 Dec 2025

Pharmacological Strategies to Overcome Immune Checkpoint Inhibitor Resistance in Non-Small Cell Lung Cancer

in Cancer Molecular Targets and Therapeutics

Dong Shang
Cailin Zhu

Frontiers in Oncology

118 views

Review

Accepted on 05 Dec 2025

Mitophagy in Gastrointestinal Tumors: Mechanisms and New Targets for Immunotherapy

in Cancer Molecular Targets and Therapeutics

Tao Zhang
Zhetan Ren
Bowen Tang
Ru Man
Lin Wang
Qingyan Wang
Jirun Peng
Yu Yongduo

Frontiers in Oncology

107 views

Original Research

Accepted on 05 Dec 2025

Efficacy and Safety of Laparoscopic Pancreaticoduodenectomy Combined with a Modified Perioperative Intraperitoneal Chemotherapy Regimen in Resectable Pancreatic Head Cancer: A Dual-Center Retrospective Cohort Study

in Surgical Oncology

Ang Li
Yu Zhang
Yue Zhang
Jianhua Liu
Feng Feng
Chen Xu
Fengshan Li

Frontiers in Oncology

34,173 articles

articles

Human fibrosarcoma cells selected for ultra-high doxorubicin resistance, acquire trabectedin cross-resistance, remain sensitive to recombinant methioninase, and have increased c-MYC expression

Rapidly evolving therapeutic advances for classical EGFR-mutant NSCLC

LncRNA ZFHX4-AS1 initiates an oncogenic axis involving a ZFHX4/SOX2 positive feedback loop to accelerate glioma progression

Molecular mechanisms and translational advances in bladder cancer: from driver genes to precision therapy

Vitiligo associated with ribociclib therapy: a rare case report

DDX49 as a novel prognostic biomarker regulates colorectal cancer cell proliferation through the TIMM44-PI3K-AKT pathway

Case Report: Successful management of high-volume paclitaxel extravasation with hyaluronidase and dry warm compresses

Prognostic value of serum free light chain abnormalities in diffuse large B-cell lymphoma

CD58 reshapes the immunosuppressive microenvironment in gliomas through PD-L1 upregulation

A novel approach for proton therapy pencil beam scanning patient specific quality assurance using an integrated detector system and 3D dose reconstruction

The impact of environmental contaminants, air pollution, and social deprivation on childhood leukemia survival in California

A novel approach to enhance beta-sitosterol bioavailability isolated from Jurinea macrocephala (a high-altitude) plant in biodegradable chitosan against lung cancer

Epidemiological profile of patients with malignant neoplasm admitted to a tertiary care center in India: a retrospective cross-sectional study

A phase Ib/II study of modakafusp alfa alone and in combination with pembrolizumab in patients with advanced or metastatic solid tumors

Rapid postoperative platelet decline in a lung adenocarcinoma with sarcomatoid differentiation and concomitant JAK2 V617F mutation: a case report

18F-PSMA-1007 versus 18F-FDG PET/CT in the detection of hepatocellular carcinoma

Cardiac Substructure Dosimetry in Postoperative Breast-Conserving Radiotherapy: A Novel 8-Field IMRT Approach for Internal Mammary Node Irradiation Using MONACO

Infection Risks Associated with Daratumumab-Containing Regimens in Multiple Myeloma: A Systematic Review and Meta-Analysis

Brachytherapy stents versus conventional plastic stents for the treatment of malignant ureteral obstruction: initial experience

Quality and Accuracy of Radiomics Models in Predicting KRAS Status in Lung Cancer: A Systematic Review and Meta-Analysis

Kinetic and radiomic features on DCE-MRI as a predictor for axillary lymph node metastasis burden in T1 and T2 stage breast cancer

Pharmacological Strategies to Overcome Immune Checkpoint Inhibitor Resistance in Non-Small Cell Lung Cancer

Mitophagy in Gastrointestinal Tumors: Mechanisms and New Targets for Immunotherapy

Efficacy and Safety of Laparoscopic Pancreaticoduodenectomy Combined with a Modified Perioperative Intraperitoneal Chemotherapy Regimen in Resectable Pancreatic Head Cancer: A Dual-Center Retrospective Cohort Study