Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 22 Oct 2025

CU06-1004 inhibits the progression of chronic colitis and colitis-associated colorectal cancer by suppressing inflammation

in Inflammation Pharmacology

Dongyeop Kim
Yeomyeong Kim
Haiying Zhang
Ye-Seul Kim
Minyoung Noh
Cho-Rong Bae
Young-Guen Kwon
Sang-Jun Ha

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684870

277 views

Original Research

Accepted on 21 Oct 2025

Modulation of TNFα-driven neuroinflammation by Gardenin A: Insights from In Vitro, In Vivo, and In Silico studies

in Inflammation Pharmacology

Prashsti Chadha
Hiral Aghara
Harshrajsinh Solanki
Manali Patel
Dhrubjyoti Sharma
Vijay Thiruvenkatam
PALASH MANDAL

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681403

Original Research

Published on 21 Oct 2025

The selective ERβ agonist AC 186 reduces polyinosinic:polycytidylic acid (poly I:C)-induced inflammatory responses in BEAS-2B lung epithelial cells

in Inflammation Pharmacology

Olumayokun A. Olajide
Hope A. Ogiogio

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1706638

289 views

Systematic Review

Accepted on 20 Oct 2025

Clinical Benefits and Complication Profile of IL-23 Inhibitors in Patients with Psoriatic Arthritis: A Systematic Review and Meta-Analysis

in Inflammation Pharmacology

Jingxin Zeng
Ling Lin
Wei Li
Xinjing Gao
Qian Li
Xin Zhou
Weiyu Liu
Xuelian Zhong
Yunqing Yang
Xibao Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669786

113 views

Original Research

Accepted on 20 Oct 2025

Regulation of inflammatory pathways by cannabigerol in the collagen induced arthritis model in rats

in Inflammation Pharmacology

Monika Šteigerová
Michaela Sklenárová
Mykhaylo Bazyuk
Luděk Záveský
Petr Jelínek
Mahak Arora
Daniel Stránský
Tomáš Kučera
Bruno Sepodes
Miroslav Šoóš

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1705962

Original Research

Published on 17 Oct 2025

A double layer oral film loaded with doxepin hydrochloride for the treatment of chemotherapy-induced oral mucositis

in Inflammation Pharmacology

Peiyan Wang
Tianlu Wang
Hui Zhang
Pei Sun
Changqing Yuan
Yiqing Guo
Zhaochen Liu
Mengyu Jiao
Jingwen Chi
Kexin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673190

387 views

Systematic Review

Accepted on 15 Oct 2025

Efficacy of pharmacological interventions and therapeutic exercises for rheumatoid arthritis: a systematic review and meta-analysis

in Inflammation Pharmacology

Timothy Adeyemi
Vitalis Ikenna Chukwuike
Motunrayo Adebukunola Oladimeji
Ufuoma Shalom Ahwinahwi
Victor Ayodeji Ayeni
Aisha Adam Abdullahi
Abdulmuminu Isah
Love Bukola Ayamolowo
Oluchukwu Perpetual Okeke
Olunike Abodunrin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1686128

180 views

Original Research

Accepted on 15 Oct 2025

Acetyl-11-keto-beta-boswellic acid ameliorates monosodium iodoacetate-induced osteoarthritis in rats: Implications of HMGB1/TLR4 /NF-κB, Nrf2/HO-1

in Inflammation Pharmacology

Amira A El-gazar
Hagar Belal Abo-zalam
Abdallah Mohammed
Bassam Mohamed Ali
Ghada M. Ragab
Heba Selim
Najat O. Hamed
Fatemah Alherz
Asmaa Saleh
Einas Yousef

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694803

Original Research

Accepted on 15 Oct 2025

1-Stearoyl-2-Arachidonoyl-Driven B Cell Metabolic Dysregulation in Chronic Rhinosinusitis with Nasal Polyps: Insights from Mendelian Randomization and Single-Cell RNA Sequencing

in Inflammation Pharmacology

Jian Wu
Yifang Sun
Shuyue Wang
倩张
Ying Lin
Caipeng Liu
Maomao Ai
Feng Yu
Lei Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1719897

128 views

Review

Accepted on 15 Oct 2025

AMPK signaling in osteoarthritis: from mechanisms to targeted therapeutics

in Inflammation Pharmacology

Lin Chen
Xiu-Hua Hu
Xin-Yi Wu
Xin Zhang
Yu-Xin Han
Yi Liu
Guangyao Chen
Qing-Wen Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681610

Review

Accepted on 14 Oct 2025

Epigenetic programming reshapes innate immune memory: decoding the molecular imprint of gouty inflammation

in Inflammation Pharmacology

Wenjie Su
Zhiqiang Luo
Yifan Lu
Hui Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678958

180 views

Opinion

Published on 09 Oct 2025

Potential strategies for combination therapy involving medicines with differential signal transduction regulation effects and the mechanism of action of minocycline in septic neuroinflammation

in Inflammation Pharmacology

Kazuhiro Itoh
Hiroshi Tsutani
Yasuhiko Mitsuke
Masamichi Ikawa
Hiromichi Iwasaki

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691613

584 views

Clinical Trial

Published on 07 Oct 2025

Preemptive flurbiprofen axetil for sleep-pain-inflammation modulation after laparoscopic gynecological surgery: a prospective, parallel-group randomized controlled trial

in Inflammation Pharmacology

Xin Huang
Wenxin Wei
Zhihao Leng
Bijia Song
Ming Fu
Jiangshan He
Junchao Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1659179

769 views

Correction

Published on 07 Oct 2025

Correction: Anti-inflammatory effect and mechanism of stytontriterpene D on RAW264.7 cells and zebrafish

in Inflammation Pharmacology

Chuqin Yu
Gao Qiu
Xiangying Liu
Quanwei Xie
Zonghao Lin
Feng Wang
Lei Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1620902

298 views

Original Research

Published on 03 Oct 2025

Decoding monocyte heterogeneity in sepsis: a single-cell apoptotic signature for immune stratification and guiding precision therapy

in Inflammation Pharmacology

Wenjuan Duan
Qi Chen
Wei Li
Haiying Zhou
Xiaorong Deng
Yan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675887

2,376 views

Review

Published on 01 Oct 2025

Advances in drug delivery systems for the management of gout and hyperuricemia

in Inflammation Pharmacology

Zining Peng
Fanyu Meng
Qian Deng
Yuanbo Huang
Danning Mao
Yuan Long
Weitian Yan
Jiangyun Peng
Xingqiang Wang
Nian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1660890

1,658 views