Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 10 Dec 2025

Isoliensinine confers neuroprotection and alleviates LPS-induced neuroinflammation in microglia by regulating the MAPK/NF-κB signaling

in Inflammation Pharmacology

Mengqin Yuan
Jinda Hu
Lichen Gao
Wei Long
Sirui Wang
Xinyue Tan
Jinyue Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675865

215 views

Review

Published on 10 Dec 2025

Immune modulation in inflammatory bowel disease: therapeutic promise of baicalein

in Inflammation Pharmacology

Yang Wang
Luyao Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1723606

183 views

Review

Accepted on 09 Dec 2025

Molecular insights into NLRP3 inflammasome and miRNA modulation in oral cancer

in Inflammation Pharmacology

Deborah Mannino
Morena D'Ariano
Ivana Bello
Irene Paterniti
Giovanna Casili
Elisabetta Panza

Frontiers in Pharmacology

168 views

Review

Accepted on 08 Dec 2025

Cycloastragenol in Inflammation-Related Diseases: Mechanisms, Pharmacokinetics, and Translational Prospects

in Inflammation Pharmacology

Chun Zhao
Xiuhua Yang
Man Yao
Xiaoxuan Song
Pilong He

Frontiers in Pharmacology

Original Research

Accepted on 04 Dec 2025

Inflammatory Response in CF Airway Epithelial Cells: A Comparative Study of Modulators and Wild-Type CFTR Rescue

in Inflammation Pharmacology

Camille Lyko
Amal Kouadri
Johanna Cormenier
Kevin Gemy
NADIA ALFAIDY
Mohamed Benharouga

Frontiers in Pharmacology

Systematic Review

Published on 04 Dec 2025

Effectiveness and safety of tocilizumab in refractory noninfectious uveitis: a systematic review and meta-analysis

in Inflammation Pharmacology

Huanmin Kang
Xue Wu
Hanyue Xu
Yufan Huang
Ming Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694311

429 views

Mini Review

Published on 04 Dec 2025

CX3CR1: a potential microglia-specific PET imaging target in Alzheimer’s and Parkinson’s diseases

in Inflammation Pharmacology

Hongzhi Yang
Yanli Wang
Yulong Xu
Changning Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678159

297 views

Original Research

Published on 03 Dec 2025

The clinical value of PLR, NLR, and MLR in predicting mortality risk in hospitalized patients

in Inflammation Pharmacology

Guoxiang Fang
Yunfei Mo
Yangwen Bao
Chunbiao Gao
Qiuya Pan
Tongbo Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1736947

478 views

Review

Published on 03 Dec 2025

Dapansutrile in multidisciplinary therapeutic applications: mechanisms and clinical perspectives

in Inflammation Pharmacology

Fuwei Bai
Dongyang Wang
Yingying Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1731165

381 views

Original Research

Accepted on 02 Dec 2025

Neoantigen immune responses in healthy volunteers: insights from multiple integrated keyhole limpet hemocyanin challenge studies on repeated immunization and response covariates

in Inflammation Pharmacology

Micha N. Ronner
Marieke De Kam
Silke van Reeuwijk
Jacobus Burggraaf
Manon AA Jansen
Matthijs Moerland

Frontiers in Pharmacology

Opinion

Published on 02 Dec 2025

CCR5-targeted γδ CAR-T cells: a rational step toward HIV-resistant allogeneic immunotherapy

in Inflammation Pharmacology

Lina Hu
Haiyan Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1734423

338 views

Original Research

Published on 01 Dec 2025

Acetyl-11-keto-beta-boswellic acid ameliorates monosodium iodoacetate-induced osteoarthritis in rats: implications of HMGB1/TLR4/NF-κB and Nrf2/HO-1

in Inflammation Pharmacology

Hagar B. Abo-Zalam
Abdallah M. Gendy
Bassam Mohamed Ali
Ghada M. Ragab
Heba Mohammed Refat M. Selim
Najat O. Hamed
Fatemah A. Alherz
Asmaa Saleh
Einas M. Yousef
Amira A. El-Gazar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694803

514 views

Review

Accepted on 30 Nov 2025

Flavonoids in inflammatory bowel disease: Multi-dimensional mechanisms via modulation of the intestinal barrier-microbiota-immune axis

in Inflammation Pharmacology

Haodong Cui
Zhilei Li
Huan Dong
Zhuo Liu

Frontiers in Pharmacology

Original Research

Accepted on 28 Nov 2025

Oleanolic Acid Cubic Liquid Crystal Nanoparticle-Based Thermosensitive Gel Attenuates Knee Osteoarthritis Symptoms in Rats

in Inflammation Pharmacology

Zhiqi Shi
Qing Li
Fan Jia
Xiaoyu Tang

Frontiers in Pharmacology

Original Research

Published on 28 Nov 2025

Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis

in Inflammation Pharmacology

Bianca Portugal Tavares de Moraes
Isabelle Moraes-de-Souza
Gabrielle Lacerda de Souza Gomes-Reis
Marina Ferreira-Costa
Carolina Medina Coeli da Cunha
Matheus Augusto Patrício de Almeida
Vanessa Estato
Kauê Francisco Corrêa Souza e Souza
Francisco da Silva dos Santos
Maria Alice dos Santos Mascarenhas Brito

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1708348

776 views

Systematic Review

Accepted on 26 Nov 2025

Comparative Efficacy and Safety of Imrecoxib versus Celecoxib: A Systematic Review and Meta-Analysis

in Inflammation Pharmacology

Xian Zeng
Lilin Dai
Zude Li
Xiaomin Dong
Zengzhen Liao
Liji Chen
Yuan Tan
Wei CHEN

Frontiers in Pharmacology

127 views