Frontiers in Pharmacology | Neuropharmacology

Editorial

Published on 25 Apr 2025

Editorial: Interplay between chronic pain and affective-cognitive alterations: shared neural mechanisms, circuits, and treatment

in Neuropharmacology

Luca Posa
Danilo de Gregorio
Serena Boccella
Kelly Smart

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605670

145 views

Systematic Review

Published on 25 Apr 2025

Effectiveness and safety of single anti-seizure medication as adjunctive therapy for drug-resistant focal epilepsy based on network meta-analysis

in Neuropharmacology

Nian-Jia Deng
Xin-Yi Li
Zhi-Xin Zhang
Chen-Yang Xian-Yu
Yu-Ting Tao
Yu-Tong Ma
Hui-Jun Li
Teng-Yu Gao
Xin Liu
Jie Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500475

Original Research

Published on 25 Apr 2025

In vitro and in-vivo exploration of physostigmine analogues to understand the mechanistic crosstalk between Klotho and targets for epilepsy

in Neuropharmacology

Mansi Dahalia
Haya Majid
Mohd Junaid Khan
Akshat Rathi
Mohd Ashif Khan
Imran Ahmd Khan
Mohammed Samim
Sayeed Ur Rehman
Md Salik Noorani
Divya Vohora

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580943

262 views

Mini Review

Published on 25 Apr 2025

Trace amine-associated receptors as potential targets for the treatment of anxiety and depression

in Neuropharmacology

Zelong Li
Luoting Wan
Jing Dong
Jinquan Li
Jianfeng Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598048

106 views

Original Research

Published on 25 Apr 2025

Suicidal thoughts and behaviors associated with fluoroquinolone antibiotics: a real-world pharmacovigilance analysis

in Neuropharmacology

Lijuan Yang
Congqin Chen
Lingqing Ding
Tingting Lu
Xiwen Li
Jie Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556159

153 views

Original Research

Accepted on 24 Apr 2025

Protective effects of AER-271 in acute-phase radiation-induced brain injury in rats: reduction of brain edema, inflammation, apoptosis and maintenance of blood-brain barrier integrity

in Neuropharmacology

Yaozu Xiong
Yifei Wang
Mingyue Li
Changhua Yu
Yusuo Tong
Xiaoting Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534729

Review

Accepted on 24 Apr 2025

Microglial Dynamics and Emerging Therapeutic Strategies in CNS Homeostasis and Pathology

in Neuropharmacology

Jie Cao
Jianqing Yuan
Nanhai Liu
Kai Huang
Mingwei Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577809

Case Report

Accepted on 24 Apr 2025

Case report：Analysis of the efficacy and safety of anti-infectious treatment for brain abscess caused by oral anaerobes

in Neuropharmacology

Chunfang Tian
Jingxian Liu
Zhiyu Chen
Lixia Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1506879

Original Research

Published on 24 Apr 2025

Multi-target neuroprotection by dl-PHPB in APP/PS1 mice: a proteomic analysis

in Neuropharmacology

Yingni Sun
Guoliang Bai
Kangmin Yang
Yong Feng
Hongmei Sun
Li Xian
Hongwei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554168

193 views

Original Research

Published on 24 Apr 2025

Exploring the diagnostic potential of IL1R1 in depression and its association with lipid metabolism

in Neuropharmacology

Yao Gao
Xiao-Na Song
Nan Zhang
Huang-Hui Liu
Jian-Zhen Hu
Xin-Zhe Du
Guo-Hua Song
Sha Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519287

234 views

Systematic Review

Published on 24 Apr 2025

Tailoring dual antiplatelet therapy for stroke prevention: a meta-analysis of timing, duration, regimen, and stroke subtypes

in Neuropharmacology

Naif M. Alhawiti
Sherouk Fouda
Naser D. Alotaibi
Hassan A. Madkhali
Fahad K. Alsharef
Jamal M. Alhawiti
Ashraf El-Metwally

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516402

198 views

Editorial

Accepted on 23 Apr 2025

Editorial: World No-Tobacco: Effects of Tobacco and Nicotine on the Brain

in Neuropharmacology

Isis Nem de Oliveira Souza
Graciela Noemí Balerio
Vijayapandi Pandy
Massimo Grilli
Gilda Angela Neves

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610178

108 views

Original Research

Published on 23 Apr 2025

Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression

in Neuropharmacology

Sarah Delcourte
Amel Bouloufa
Renaud Rovera
Elie Brunet
Hiep D. Le
April E. Williams
Satchidananda Panda
Rihab Azmani
Olivier Raineteau
Ouria Dkhissi-Benyahya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592909

289 views

Review

Published on 23 Apr 2025

Efficacy, safety, and tolerability of soticlestat (TAK-935) as adjunctive therapy in pediatric patients with dravet syndrome and Lennox–Gastaut syndrome: a meta-analysis of 3 randomized controlled trials

in Neuropharmacology

Zhang Lanlan
Jiang Nana
Wang Chengzhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586098

330 views

Original Research

Published on 23 Apr 2025

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors

in Neuropharmacology

Ornella Valenti
Katarzyna Anna Rekawek
Sophie Wieser
Hilal Bulut
Petra Scholze
Stefan Boehm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534101

149 views

Original Research

Accepted on 22 Apr 2025

Tetramethylpyrazine Enhances Neuroprotection and Plasticity in Cerebral Ischemia-Reperfusion Injury via RhoA/ROCK2 Pathway Inhibition

in Neuropharmacology

Yixin Zhang
Xin Zhang
Xiaocheng Shi
Weijing Liao
Junbin Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1594283