Frontiers in Pharmacology | Neuropharmacology

Systematic Review

Published on 29 Oct 2025

Comparative safety and tolerability of ketamine and esketamine for major depressive disorder: a systematic review and meta-analysis

in Neuropharmacology

Haoning Guo
Liling Tang
Miaoquan He
Wencheng Tang
Jing Liu
Silin Wu
Shuying Yuan
Jisheng Wang
Xueli Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681060

191 views

Original Research

Published on 29 Oct 2025

The neuroprotective effect of cannabidiol is enhanced by resveratrol and alpha-lipoic acid in social isolation

in Neuropharmacology

Federica Ricciardi
Andrea Maria Morace
Rebecca Limongelli
Monica Iannotta
Serena Boccella
Antimo Fusco
Roozbe Bonsale
Michela Perrone
Rosmara Infantino
Emanuele Di Martino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1676421

283 views

Original Research

Published on 29 Oct 2025

Exposure to β-hydroxybutyrate reduces the operating set point and increases excitability in hippocampal circuitry of healthy mice

in Neuropharmacology

Thais Tessari Zampieri
Guilherme Shigueto Vilar Higa
Fernando S. Borges
Felipe José Costa Viana
Emily Cruvinel
Lucas Eduardo Bentivoglio
Ademar Benevolo Lugao
Henning Ulrich
Luiz Roberto Britto
Kattesh V. Katti

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557612

316 views

Opinion

Accepted on 28 Oct 2025

Glucose may be biotransformed and then react with alcohol, fats, endocannabinoids, or various amino acids to form dopamine or norepinephrine in vivo

in Neuropharmacology

Paul J. Fitzgerald

Frontiers in Pharmacology

Brief Research Report

Accepted on 28 Oct 2025

NEURO-FUNCTIONAL CORRELATES OF PERSONALITY DIMENSIONS IN PARKINSON'S DISEASE

in Neuropharmacology

Mathilde Boussac
Estelle Harroch
Karel Joineau
Emeline Descamps
Christine Brefel-Courbon

Frontiers in Pharmacology

Original Research

Published on 28 Oct 2025

The involvement of GABA-rho receptors in regulating ethanol-induced elevation of dopamine, glycine and taurine within the nucleus accumbens of Wistar rats

in Neuropharmacology

Davide Cadeddu
Anna Loftén
Karin Ademar
Bo Söderpalm
Louise Adermark
Mia Ericson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1668669

850 views

Original Research

Published on 28 Oct 2025

Serum amyloid A-mediated neuro-inflammation induces hippocampal neuron apoptosis and postoperative cognitive dysfunction in mice

in Neuropharmacology

Xiaochen Fu
Zhenbin Cai
Yuxuan Wu
Yiwen Xu
Ze Gao
Minghui Tan
Jing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661881

1,070 views

Review

Accepted on 27 Oct 2025

The role of Panax Notoginseng Saponins in cerebrovascular neurological disorders: an overview of mechanisms and functions

in Neuropharmacology

Bin Wang
Zhouying Shi
Xu Gao
Yali Zhang
Yuhua Xiao
Tong Chen
Yue Yuan
Ping Li

Frontiers in Pharmacology

109 views

Original Research

Accepted on 27 Oct 2025

Time-Dependent Biphasic Alterations in Brain Metabolism Following Chronic Ketamine Exposure in Mice

in Neuropharmacology

Seohyun Lim
Young Suk Choi
Chul Hoon Kim
Eo Su Kim
Ho Taek Song

Frontiers in Pharmacology

136 views

Original Research

Published on 27 Oct 2025

Study on Chaiyuwendan decoction’s inhibition of hippocampal neuron apoptosis to alleviating depression by activating the AKT/CREB pathway

in Neuropharmacology

Shaoliang Zhang
Sijie Cheng
Huiqing Liang
Yan Qiu
Jie Ren
Yv Huang
Bangyan Zhou
Chunrong Li
Jingmin Zhang
Tianxiang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610899

1,778 views

Original Research

Published on 27 Oct 2025

Neuroprotective mechanisms of valproic acid and alpha-lipoic acid in ALS: a network pharmacology-based investigation

in Neuropharmacology

Dongmei Zhang
Ling Han
Wenmo Zhang
Di Wang
Di Huo
Xingli Tan
Xiaoli Su
Ming Wang
Jing Xu
Jiling Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681929

1,826 views

Original Research

Accepted on 24 Oct 2025

Molecular genetic basis of the primary emotions in young adults: An exploratory analysis of genetic polymorphisms across dopamine, serotonin, oxytocin, endogenous opioid, and neurotrophic factor pathways

in Neuropharmacology

Timotej Glavač
Maruša Barbo
Metka Ravnik-Glavač
Maja Zupančič
Vita Dolzan

Frontiers in Pharmacology

371 views

Original Research

Accepted on 24 Oct 2025

The Development and verification of clinical medication pathway for tic disorder in west China

in Neuropharmacology

Chunsong Yang
Dan Li
Jianhua ZHANG

Frontiers in Pharmacology

331 views

Original Research

Published on 24 Oct 2025

Hydrogen sulphide alleviates depression-like behaviors by suppressing the hippocampal necroptosis-neuroinflammation-KP imbalance axis

in Neuropharmacology

San-Qiao Yang
Yu-Hui Tang
Si-Min Chen
Fen Liu
Ping Zhang
Wei Zou
Bo Wang
Xiao-Qing Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691204

3,926 views

Mini Review

Accepted on 23 Oct 2025

Post-Traumatic Epilepsy: Bridging Pathogenesis, Diagnosis, and Pharmacotherapeutic Strategies

in Neuropharmacology

Xiaoyu Yang
Siyang Chen
Haozhou Wang
Ke Wu
Tong Sun

Frontiers in Pharmacology

279 views

Original Research

Accepted on 22 Oct 2025

Efficacy Analysis of Remifentanil Mild Sedation Anesthesia for Painless Gastroscopy

in Neuropharmacology

Dongfeng Xi
Huiling Zhang
Mengyuan Gu
Yao Wang
Jiangbo Qu
Huibin Mao
Lina Mi
Bin Li

Frontiers in Pharmacology

314 views