Frontiers in Pharmacology | Neuropharmacology

Mini Review

Published on 10 Oct 2025

Dexmedetomidine for postoperative delirium in surgical patients: a mini-review of mechanisms, clinical evidence, and practical implementation

in Neuropharmacology

Xiao-yan Li
Jing-yi Yang
Yi Qiu
Cai-xia Wang
Xiao-dong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1702862

305 views

Original Research

Accepted on 09 Oct 2025

The neuroprotective effect of cannabidiol is enhanced by resveratrol and alpha-lipoic acid in social isolation

in Neuropharmacology

Federica Ricciardi
Andrea Maria Morace
Rebecca Limongelli
Monica Iannotta
Serena Boccella
ANTIMO FUSCO
Roozbe Bonsale
Michela Perrone
Rosmara Infantino
Emanuele Di Martino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1676421

Original Research

Accepted on 08 Oct 2025

Hydrogen sulphide alleviates depression-like behaviors by suppressing the hippocampal necroptosis-neuroinflammation-KP imbalance axis

in Neuropharmacology

San-Qiao Yang
Yu-Hui Tang
Si-Min Chen
Fen Liu
Ping Zhang
Wei Zou
Xiao-Qing Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1691204

Original Research

Accepted on 08 Oct 2025

Study on Chaiyuwendan Decoction's Inhibition of Hippocampal Neuron Apoptosis to Alleviating Depression by Activating the AKT/CREB Pathway

in Neuropharmacology

Shaoliang Zhang
Sijie Cheng
Huiqing Liang
Yan Qiu
Jie Ren
Yv Huang
Bangyan Zhou
Chunrong Li
Jingmin Zhang
Tianxiang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610899

Original Research

Accepted on 08 Oct 2025

Integerated metabolomics and gut microbiota analysis to explore protential mechanism of levo-tetrahydropalmatine against ketamine addiction

in Neuropharmacology

Yan Du
Qing Ma
Xingcui Gao
Hongliang Su
Keming Yun
Li Du

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1698866

Review

Published on 08 Oct 2025

Anti-inflammatory effect of curcumin on neurological disorders: a narrative review

in Neuropharmacology

Baoyin Zhou
Binbin Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658115

594 views

Original Research

Published on 08 Oct 2025

Dopaminergic REST is implicated in the tamoxifen-induced neuroprotection against manganese toxicity in female mice

in Neuropharmacology

Edward Pajarillo
Alexis Digman
Itunu Ajayi
Sanghoon Kim
Deok-Soo Son
Michael Aschner
Eunsook Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1627400

408 views

Original Research

Published on 08 Oct 2025

Prophylactic administration of metformin alleviates withdrawal symptoms associated with heroin

in Neuropharmacology

Minghong Liu
Junyu Jiang
Xiaolong Wu
Jiaxin Liu
Yang Liu
Shanshan Ling
Huichun Chen
Gongliang Zhang
Yuanhai Li
Gang Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1647624

488 views

Original Research

Published on 07 Oct 2025

3-Hydroxytyrosol as a phenolic cholinesterase inhibitor with antiamnesic activity: a multimethodological study of selected plant phenolics

in Neuropharmacology

Tugba Ucar Akyurek
F. Sezer Senol Deniz
Ipek Suntar
Gokcen Eren
Onur Kenan Ulutas
Ilkay Erdogan Orhan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1640034

1,125 views

Study Protocol

Published on 07 Oct 2025

Synergistic effect of Chaihu-Shugan-San combined with paroxetine tablets in the treatment of acquired premature ejaculation: study protocol for a randomized controlled proof-of-concept trial

in Neuropharmacology

Shengqiang Qian
Jintao Wei
Peihai Zhang
Ziyang Ma
Yu Guo
Feiqiang Ren
Wei Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1651654

809 views

Review

Published on 07 Oct 2025

Rheumatoid arthritis-associated depression: focusing on the interactions between mitochondria and endoplasmic reticulum

in Neuropharmacology

Mingqin Shi
Xinyao Li
Haimei Zhou
Zhenmin Li
Yuanyuan Wei
Zihui Wang
Yuqing She
Xuelian Zou
Xiangdian Xiao
Jiashun Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549060

926 views

Original Research

Published on 07 Oct 2025

Computational and experimental identification of putative αTAT1 modulators: implications for nervous system function

in Neuropharmacology

Oksana Rybachuk
Alexey Rayevsky
Mariia Styhylias
Dariia Samofalova
Elijah Bulgakov
Maxym Platonov
Yaroslav Blume
Pavel Karpov

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1654114

822 views

Original Research

Accepted on 06 Oct 2025

NeuproGemp, a Polyphenol-Rich Botanical Formula, Ameliorates Alzheimer's-like Pathology in APP/PS1 Mice via Inhibition of Human Glutaminyl Cyclase

in Neuropharmacology

Tien Sheng Tseng
Chia-Ching Liaw
Young-Ji Shiao
Ya-I Huang
Yu-Hsiu Cheng
Wang-Chuan Chen
Keng-Chang Tsai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673532

Systematic Review

Accepted on 06 Oct 2025

Systematic Review and Network Meta-Analysis of the effects of Bioactive Compounds on pain intensity and quality of life in neuropathic pain patients

in Neuropharmacology

Rong Tang
Chao-Yang Gong
Yu-Qian Liu
Yingbin Wang
Hai-Yu Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656400

Original Research

Accepted on 01 Oct 2025

Evaluating the Risk of Osteopenia-Related Adverse Events with Antiepileptic Drugs: A Pharmacovigilance Study Based on the FAERS Database

in Neuropharmacology

Nan Yang
Xiang Han
Hongning Hua
Yumeng Wang
Yulin Chen
Yue Zhou
Haoyu Feng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1685289

165 views

Original Research

Published on 01 Oct 2025

Ferulic acid mitigates 3-Nitropropionic acid-induced Huntington’s disease via modulation of Nrf2/HO-1, TLR4/NF-κB, and SIRT1/p53 signaling pathways

in Neuropharmacology

Mohamed A. Abdelgawad
Abdallah M. Gendy
Sameh S. Zaghlool
Wessam H. Elesawy
Mai F. Ragab
Mohamed I. Kotb El-Sayed
Alaadin E. El-Haddad
Hussein S. Mohamed
Izzeddin Alsalahat
Marwa A. Essa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678724

1,070 views