Frontiers in Pharmacology | Predictive Toxicology

Original Research

Published on 01 Jul 2025

A retrospective observational study on case reports of adverse drug reactions (ADRs) to tirzepatide

in Predictive Toxicology

Mengmeng Huang
Guangwei Liu
Chuanzhou Zhang
Ying Wang
Shengfen Liu
Jun Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1608657

463 views

Original Research

Accepted on 30 Jun 2025

Osteoporosis diagnosis and ingredients of prescription medications: a population-based study

in Predictive Toxicology

Xiaohong Huang
Zhendong Feng
Xiaohua Li
Dongxu Zhu
Yingze Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522937

Review

Published on 26 Jun 2025

Gastrointestinal stromal tumors with the use of ripretinib and sunitinib: real-world adverse event analysis based on the FDA adverse event reporting system (FAERS)

in Predictive Toxicology

Xinzhen Che
Yong Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561937

336 views

Original Research

Accepted on 13 Jun 2025

An occupational pipe leak poisoning

in Predictive Toxicology

Xiangxing Zhang
Tianzi Jian
Mengdi Shi
Chen Wang
Xiangdong Jian
Qilu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514565

111 views

Original Research

Published on 13 Jun 2025

Molecular mechanisms of polychlorinated biphenyls in breast cancer: insights from network toxicology and molecular docking approaches

in Predictive Toxicology

Xiaoyu Yang
Wenlong Liang
Zhenchu Feng
Guangyan Li
Xi Chen
Jianguo Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1604993

873 views

Original Research

Published on 27 May 2025

Organ-specific safety profile of bioinspired short antimicrobial peptides in zebrafish embryos

in Predictive Toxicology

Sahar Isa Da’as
Hajira Afreen
Aseela Fathima
Ahmad M. Hani
Nura A. Mohamed
Md Mizanur Rahman
Patrick G. Burgon
Sergio Crovella
Haissam Abou-Saleh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593683

856 views

Original Research

Published on 12 May 2025

Exploring the mechanisms and targets of proton pump inhibitors-induced osteoporosis through network toxicology, molecular docking, and molecular dynamics simulations

in Predictive Toxicology

Yaqi Mu
Yaqi Zhou
Xinan Zhang
Yiming Shao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592048

1,801 views

Editorial

Published on 17 Apr 2025

Editorial: Model organisms in predictive toxicology 2023

in Predictive Toxicology

Cristina Luceri
Abdulahad Dogan
Angel León-Buitimea

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1609126

815 views

Original Research

Published on 15 Apr 2025

Acute and subacute toxicity evaluation of ZhenzhuXiaoji decoction in preclinical models: implications for safe clinical use

in Predictive Toxicology

Songzhe Li
Shuchang Bao
Lingyun Cai
Baolong Li
Yue Sun
Yang Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554732

1,149 views

Original Research

Published on 08 Apr 2025

Risk of medication-induced lactic acidosis and hyperlactatemia: a pharmacovigilance study of the United States Food and Drug Administration’s Adverse Event Reporting System database

in Predictive Toxicology

Houci Yang
Haibin Dai
Xveying Chen
Jiaqi Huang
Fangzhou Miao
Jiani Lv
Jiali Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555955

2,626 views

Case Report

Published on 05 Mar 2025

Transdermal fentanyl induced paralytic intestinal obstruction in advanced liver cancer: a case report

in Predictive Toxicology

Chen Li
Jindong Chu
Xiaodong Jia
Haibin Su

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550296

1,718 views
1 citation

Original Research

Published on 28 Feb 2025

Blood compatibility evaluation of polydopamine nanoparticles

in Predictive Toxicology

Sha Li
Si-Ming Yan
Li-Wei Zhang
Xiao-Yan Yang
Zhong Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530650

1,184 views

Editorial

Published on 25 Feb 2025

Editorial: Methods in predictive toxicology 2023

in Predictive Toxicology

Sankalp Jain
Serena Manganelli
Vitalina Gryshkova
Maria Armanda Rodrigues
Aniket Magarkar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556352

1,088 views

Original Research

Published on 13 Feb 2025

Entrectinib can induce nerve cell damage by inhibiting PI3K-AKT and TGF-β signaling pathways

in Predictive Toxicology

Qingshan Tang
Jiachen Dong
Feng Zhang
Dan Zhao
Qi Yang
Jiayu Wen
Yuhao Sun
Jifu Wei
Zhixian Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1489210

1,817 views
1 citation

Original Research

Published on 06 Feb 2025

Safety assessment of rosuvastatin-fenofibrate combination in the treatment of hyperlipidemia based on FDA’s adverse event reporting system database

in Predictive Toxicology

Qun Li
Wenya Shan
Saiwei Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1415701

3,016 views
1 citation

Original Research

Published on 24 Jan 2025

MDTR: a knowledge-guided interpretable representation for quantifying liver toxicity at transcriptomic level

in Predictive Toxicology

Inyoung Sung
Sangseon Lee
Dongmin Bang
Jungseob Yi
Sunho Lee
Sun Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1398370

1,523 views
1 citation