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ORIGINAL RESEARCH article

Front. Psychol.

Sec. Health Psychology

Volume 16 - 2025 | doi: 10.3389/fpsyg.2025.1594430

Global, regional, and national burden and trends of depressive disorders among women of childbearing age from 1990 to 2021: insights from GBD 2021

Provisionally accepted
  • 1Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China
  • 2Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, China
  • 3Central South University, Changsha, Hunan Province, China
  • 4College of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong Province, China

The final, formatted version of the article will be published soon.

Background: Depressive disorders are highly prevalent and disabling mental illnesses among women of childbearing age (WCBA), especially with the surge in prevalence following the COVID-19 pandemic, but evidence on their burden remains insufficient. This study provides a thorough analysis of the burden of depressive disorders among WCBA at global, regional and national levels.Methods: This study utilized data from Global burden of disease (GBD) 2021 to evaluate the trends in incidence, prevalence, Disability-Adjusted Life Years (DALYs) of depressive disorders among WCBA from 1990 to 2021. Data was stratified by time, age, region, and socio-demographic index (SDI).Moreover, this study utilized a range of analytical methods, including estimated annual percentage change (EAPC), Joinpoint regression, decomposition analysis and predictive modeling (Nordpred method).Results: Depressive disorders in WCBA constitute a growing global health crisis, marked by a notable rise in absolute cases, accompanied by a slight downward age-standardized incidence rate (ASIR) , agestandardized prevalence rate (ASPR), and age-standardized DALYs rate (ASDALYR). In 2021, there

Keywords: Depressive disorders., Global burden of disease, GBD 2021, DALYs, Women of childbearing age

Received: 16 Mar 2025; Accepted: 25 Jul 2025.

Copyright: © 2025 Tang, Li, Shao, Li, Tang and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Zhaoming Chen, Nanjing Hospital of Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu Province, China

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