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ORIGINAL RESEARCH article

Front. Psychol.

Sec. Health Psychology

Volume 16 - 2025 | doi: 10.3389/fpsyg.2025.1623122

This article is part of the Research TopicHealth and Psychological Adaptations to Life Challenges and Stressful Conditions - Volume IIView all 3 articles

Family Resilience and Demoralization in Decompensated Cirrhosis: Parallel Mediation of Psychological Resilience and Social Support

Provisionally accepted
Haixia  GaoHaixia Gao1Gang  MaoGang Mao2Xuelian  GuXuelian Gu3Hui  WangHui Wang2Jianhua  NiuJianhua Niu2Lei  LiuLei Liu2*
  • 1Shandong First Medical University, Jinan, China
  • 2The Forth People’s Hospital of Jinan, Jian, China
  • 3The Third People’s Hospital of Jinan, Jinan, China

The final, formatted version of the article will be published soon.

This study aims to understand the relationship between psychological resilience and social support in family resilience and demoralization syndrome (DS) in decompensated cirrhotic patients and verify whether there is a parallel mediation effect. A cross-sectional design was adopted, and a questionnaire was administered to 260 patients with decompensated cirrhosis in Jinan, Shandong Province, China. The Mandarin Version of the Demoralization Scale (DS-MV) was used to assess DS. Spearman's correlation was used to analyze the relationship between family resilience, DS, psychological resilience, and social support, and predictors of DS were explored using multiple linear regression. Parallel mediation effect analysis was performed using a bootstrap test. The proportion of patients with severe DS was 18.46% of those with decompensated cirrhosis. Spearman correlation analysis demonstrated that DS was negatively correlated with psychological resilience, family resilience, and social support (r=-0.738, p < 0.01; r=-0.668, p < 0.01; r=-0.405, p < 0.01). Multiple linear regression analysis showed that psychological resilience (β=-0.477, p <0.001), family resilience (β=-0.364, p <0.001), and social support (β=-0.108, p =0.01) could influence DS of decompensated cirrhotic patients. Bootstrap analysis confirmed a significant parallel mediation effect of psychological resilience and social support (95% CI: -0.999 to -0.499), accounting for 51.93% of the total effect. Family resilience had a significant direct effect (95% CI: -0.995 to -0.356), accounting for 48.07% of the total effect. Therefore, attention should be paid to DS in decompensated cirrhotic patients. Family resilience, psychological resilience, and social support can be used to decrease the level of DS.

Keywords: decompensated cirrhotic patients, Demoralization syndrome, family resilience, psychological resilience, social support, parallel mediation effect

Received: 07 May 2025; Accepted: 14 Jul 2025.

Copyright: © 2025 Gao, Mao, Gu, Wang, Niu and Liu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Lei Liu, The Forth People’s Hospital of Jinan, Jian, China

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