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ORIGINAL RESEARCH article

Front. Psychol.

Sec. Environmental Psychology

Volume 16 - 2025 | doi: 10.3389/fpsyg.2025.1657172

This article is part of the Research TopicThe Intersection of Psychology, Healthy Behaviors, and its OutcomesView all 123 articles

A Randomized Controlled Trial of Group Psychological Intervention Combined with Medication for Treating Adolescent Depression

Provisionally accepted
Xinming  YuXinming Yu1Zijun  ChenZijun Chen2,3Bin  WangBin Wang1Ke  ZhengKe Zheng1Jian  GuoJian Guo1Shikang  LiShikang Li1Liang  YuLiang Yu3*
  • 1The Second People's Hospital of Chuzhou, ChuZhou, China
  • 2Department of Laboratory Medicine, First Affiliated Hospital of Wannan Medical College, Wuhu, China
  • 3Wannan Medical College, Wuhu, China

The final, formatted version of the article will be published soon.

Objective A study of the effects of group psychotherapy on depression and anxiety in adolescents. Methods Ninety-two adolescent depression patients attending a city mental health center from May 2022 to December 2024 were selected for the study, and a randomized controlled trial design was used with 46 cases in each group. The patients in the observation group were treated with group psychotherapy combined with medication. The patients in the control group were treated with medication,for 4 consecutive weeks, and t-tests and chi-square tests were used to compare the differences in the rates of HAMA and HAMD-17 score reduction between the two groups. Results (1) The difference in HAMD-17 scores between the two groups at baseline was not statistically significant (Z=-0.455, P=0.649). In contrast, the difference in HAMA scores between the two groups at baseline was statistically significant (Z=-2.120, P=0.034). Four patients in each of the two groups dropped out of the treatment, resulting in a total dropout rate of 8%. (2) At the end of the 4-week treatment, the HAMA and HAMD-17 scores of patients in the 2 groups were significantly lower than those at baseline, and the difference in the rate of reduction in HAMA and HAMD-17 scores before and after the treatment between the observation group and the control group (89.1% versus 34.8%, and 97.8% versus 80.4%) was statistically significant (χ2=28.82, P<0.001; χ2=7.18, P=0.007), indicating clinically meaningful improvement as both rates far exceed the 50% threshold for treatment response. Conclusion After group psychotherapy combined with medication to treat depression symptoms in adolescents is more effective, it can effectively accelerate the recovery of the disease, improve negative emotions, and reduce the recurrence of the disease.

Keywords: Group psychotherapy, Adolescent, Depression, HAMA, HAMD-17

Received: 01 Jul 2025; Accepted: 15 Aug 2025.

Copyright: © 2025 Yu, Chen, Wang, Zheng, Guo, Li and Yu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Liang Yu, Wannan Medical College, Wuhu, China

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