ORIGINAL RESEARCH article
Front. Psychol.
Sec. Addictive Behaviors
A contextual behavioral model of Chemsex: structural equation modeling of psychological predictors of hypersexuality and drug use
Provisionally accepted- Department of Psychology, Faculty of Biomedical Sciences and Health, European University of Madrid, Madrid, Spain
Select one of your emails
You have multiple emails registered with Frontiers:
Notify me on publication
Please enter your email address:
If you already have an account, please login
You don't have a Frontiers account ? You can register here
Abstract Background and objective: Chemsex, defined as the intentional use of psychoactive substances in sexual contexts, is increasingly prevalent among gay and bisexual men and is associated with a range of mental, physical and social implications. This study aimed to test a contextual behavioral model examining how psychological inflexibility, loneliness, intimacy difficulties, and internalized homophobia contribute to hypersexuality and sexualized substance use. Methods: A cross-sectional study was conducted with 252 Spanish-speaking participants who reported engaging in sexualized substance use within the past year. Standardized self-report measures were used to assess psychological processes and behavioral outcomes. Structural equation modeling was employed to examine direct and indirect effects among variables. Results: The proposed path model demonstrated excellent fit (χ² = 0.002, p = .967; CFI = 1.000; RMSEA = 0.000). Psychological inflexibility showed the strongest association with both hypersexuality (β = .48, p < .001) and substance use (β = .25, p < .01), with a significant indirect effect via hypersexuality. Loneliness was also associated with both outcomes and showed mediated effects. Internalized homophobia was associated with hypersexuality but not with substance use. Intimacy was not a significant predictor. The model explained 42.1% of the variance in hypersexuality and 27.2% in substance use. Conclusion: This study offers a novel contribution by modeling chemsex-related behaviors as forms of experiential avoidance shaped by psychological inflexibility, loneliness, and internalized homophobia. The findings highlight the potential utility of Acceptance and Commitment Therapy (ACT) in reducing chemsex vulnerability by promoting psychological flexibility and values-based living.
Keywords: Chemsex, Psychological flexibility, SexualiZed drug use, Hypersexuality, Structural Equation Modeling
Received: 24 Jul 2025; Accepted: 30 Oct 2025.
Copyright: © 2025 Rico and Montesinos. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Rubén Rico, rricopa@upsa.es
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.