Inhibited Neural Response during Interpersonal Conflict: Insights from fNIRS Hyperscanning

Kang Cao^1,2Mingming Zhang³Yuxuan Zhang^3*Jie Li^1,4*

• ¹Inner Mongolia Normal University, Hohhot, China
• ²Chizhou University, Chizhou, China
• ³Shanghai Normal University, Shanghai, China
• ⁴Tianjin University of Traditional Chinese Medicine, Tianjin, China

Interpersonal conflict is a core yet complicated part of social interaction, involving complex mental and emotional processes. However, the neural mechanisms underlying interpersonal conflict are still not fully understood. This study employed functional near-infrared spectroscopy (fNIRS) hyperscanning to explore the brain activity related to interpersonal conflict through both passive video viewing and active role-playing paradigms. The results revealed an unexpected activation pattern – brain activity was highest at rest, lower during conflict, and lowest during neutral interactions (i.e., rest > conflict > neutral) in all ROIs except the rTPJ during active role-playing. This indicates a cortical deactivation effect when people engage in social processing. Additionally, the study found that inter-brain synchronization (IBS) between the two participants’ brains decreased significantly during conflict compared to non-conflict conditions. These findings provide neurocognitive evidence for disrupted interpersonal alignment during conflict and highlight potential intervention targets—such as perspective-taking and interpersonal attunement—for enhancing social functioning in challenging interactions.