ORIGINAL RESEARCH article
Front. Psychol.
Sec. Psycho-Oncology
This article is part of the Research TopicInnovations in Psychological Care for Oncology and Palliative Settings: A Holistic ApproachView all 26 articles
Investigating the Prevalence and Correlates of Anxiety and Depression Among COVID-19 Patients with and without Concomitant Tumor Conditions
Provisionally accepted- Fujian Medical University Union Hospital, Fuzhou, China
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Objective: This study aims to evaluate the prevalence of anxiety and depression in patients with novel coronavirus pneumonia (COVID-19), with and without tumors, and to identify associated factors for improving therapy and quality of life. Methods: 74 patients diagnosed with COVID-19 were form Fujian Medical University Affiliated Union Hospital from Fujian Medical University Affiliated Union Hospital were enrolled. The Hospital Anxiety and Depression Scale, Medical Coping Modes Questionnaire, Social Support Rating Scale, Type D Personality Scale, and neutrophil-to-lymphocyte ratio (NLR) were used to compare psychological status between tumor and non-tumor groups and to analyze related factors. Results: Among 74 patients, those with tumors (n=14) showed a higher prevalence of anxiety and depression than those without tumors (64.29% vs. 33.33%, p<0.05). Social support scores and NLR differed significantly between the two groups (p<0.05), whereas coping styles and type D personality did not (p>0.05). Conclusion: COVID-19 patients with tumors exhibit higher rates of anxiety and depression, affected by social support and NLR. These findings emphasize the need for early multidisciplinary interventions integrating psychological and immunological assessment.
Keywords: COVID-19, tumor, Anxiety, Depression, Prevalence, determinants
Received: 07 Oct 2025; Accepted: 26 Nov 2025.
Copyright: © 2025 Luo, Liu, Zheng, Zhang, Zhang, Weng, Chen and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Guizhen Weng
Xiangqi Chen
Sheng Yang
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