Nanochemistry in Biomaterials for Regenerative Medicine and Controlled Drug Release

In recent years, nanotechnology has garnered significant attention for its potential to revolutionize various domains of science and technology, particularly in the realm of biomaterials and drug development. Nanochemistry, a subfield of nanotechnology, involves manipulating and controlling matter at the nanoscale level, yielding materials with unique properties and applications. In the context of biomaterials and drug development, nanochemistry offers novel avenues for the design and fabrication of advanced materials and therapeutic agents, allowing for enhanced efficacy, improved targeting, and reduced side effects. Nanochemistry has also enabled the creation of biomaterials with enhanced biocompatibility, mechanical strength, and controlled release properties. Functionalization of nanomaterial surfaces with biomolecules facilitates targeted interactions with cells and tissues, promoting desirable cellular responses. The tailored design of nanocomposite biomaterials, incorporating nanoparticles with specific functionalities, offers unprecedented opportunities for controlled drug release, antimicrobial properties, and cellular signaling.

In this edition, we will showcase the latest research on biomaterials and their biological activity. The design and fabrication of biomaterials with suitable properties for tissue regeneration and medical implants is a complex task. However, by applying nanochemistry, we can engineer scaffolds with ideal mechanical properties, surface functionalities, and cellular interactions. Recent advancements in this field involve incorporating nanoparticles into scaffolds or coating biomaterial surfaces with nanomaterials to enhance cellular adhesion, proliferation, and differentiation. This, in turn, leads to accelerated healing and improved tissue integration. To overcome the challenges in this field, we need innovative solutions that leverage the principles of nanochemistry to enhance the performance of biomaterials in regenerative medicine, as well as target drug or molecule delivery. Our Research Topic aims to highlight the importance of integrating nanochemistry principles to achieve precise control over material properties and drug interactions, resulting in improved therapeutic outcomes.

We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:
• Synthesis and manipulation of biomaterials at the nanoscale
• Evaluation of the biocompatibility of nanoparticle based biomaterials
• Design and engineering multifunctional nanomaterials for biomedical applications and nanomedicine.
• Cell-nanoparticle based biomaterials interactions.
• Nano drug delivery systems

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Editorial
• FAIR² Data
• Mini Review
• Original Research
• Perspective
• Review

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Editorial
• FAIR² Data
• Mini Review
• Original Research
• Perspective
• Review

Keywords: nanoparticles, biomaterials, nanochemistry, nanomedicine, biocompatibility, cytotoxicity

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.