Determination of a representative food mass-to-surface area ratio (mF/A) for estimating migration values of food contact substances (FCS) in single use food contact articles (FCA) marketed in the United States Provisionally Accepted

Lauren M. Zhovmer^1* Andres M. GonzalezBonet¹ Madhur Garg² Allan B. Bailey¹ Kirk B. Arvidson¹

• ¹United States Food and Drug Administration, United States
• ²Oak Ridge Institute for Science and Education (ORISE), United States

When reviewing the safety of food packaging, safety assessors must determine the migration levels of a food contact substance (FCS) from the packaging into the contained food products. Migration values can be expressed relative to levels in food using a single 'food mass-to-surface area (m F /A) ratio', representative of the general food supply. Because no published literature has examined m F /A ratios for the current U.S. food supply, this study aimed to use food databases to develop a standard m F /A ratio representative of packaged foods in the current U.S. food supply. First, we obtained information on the food-contact surface area (A) and food mass (m F ) for a selection of packaged foods sold in U.S. retail stores. To adequately represent the variation of food products on the market, we identified a representative product per food category, using a 95-category list that was derived from the USDA WWEIA Food Categories. The values for A and m F per package were determined for each representative product using product size information from the Syndigo Nutrition Database. These data were used to calculate the A/m F ratio for each of the 95 representative products, and the average A/m F ratio was determined. The average A/m F ratio was weighted using consumption data from the WWEIA component of NHANES, so that more weight was given to foods that are consumed in greater quantities. The final step was to then take the reciprocal of the averaged A/m F ratio to obtain the final m F /A ratio. The resulting m F /A ratio was 4.8 g/in 2 , which rounds to 5 g/in 2 . In summary, we determined that 5 g/in 2 is representative of the current U.S. food supply and could be used as a standard m F /A ratio when estimating migration levels of an FCS from packaging into food.