Frontiers in Bioengineering and Biotechnology | Tissue Engineering and Regenerative Medicine

Original Research

Published on 10 Jul 2025

Biological effects of exosomes derived from 2D and 3D culture adipose stem cells on JEC Cell proliferation and migration

in Tissue Engineering and Regenerative Medicine

Yifen Li
Gangwei Wang
Yi Zhang
Tao Xu
Xuefeng Jiang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1541150

2,230 views
1 citation

Original Research

Published on 09 Jul 2025

Olfactory mucosal mesenchymal stem cells delivered by gelatin sponge scaffolds promote functional recovery of spinal cord injury

in Tissue Engineering and Regenerative Medicine

Wenshui Li
Xinchen Jiang
Shuo Lu
Wen Lu
Shanshan Ma
Yi Zhuo
Qingtao Gao
Yi Xiao
Binqian Wu
Junyang Xie

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1628758

2,395 views

Review

Published on 07 Jul 2025

3D visualization of uterus and ovary: tissue clearing techniques and biomedical applications

in Tissue Engineering and Regenerative Medicine

Qiqi Liu
Zhuo Song
Simin Liu
Zirui Dong
Xi Zheng
Tak Yeung Leung
Xiaoyan Chen

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1610539

4,516 views
1 citation

Original Research

Published on 30 Jun 2025

Low-intensity ultrasound lysis of amyloid microclots in a lab-on-chip model

in Tissue Engineering and Regenerative Medicine

Reza Rasouli
Brad Hartl
Soren D. Konecky

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1604447

8,630 views
5 citations

Systematic Review

Published on 20 Jun 2025

Targeting osteoarthritis with small extracellular vesicle therapy: potential and perspectives

in Tissue Engineering and Regenerative Medicine

Alba González-Rodríguez
F. Javier De Toro
Alberto Jorge-Mora
Pablo Fernandez-Pernas
Carlota Probaos Rivadulla
María Fraga
Juan A. Fafián-Labora
María C. Arufe

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1570526

4,319 views
4 citations

Original Research

Published on 18 Jun 2025

Acellular porcine placental membranes as a novel biomaterial for tissue repair applications

in Tissue Engineering and Regenerative Medicine

Gustavo Henrique Doná Rodrigues Almeida
Luan Stefani Lima
Mariana Sversut Gibbin
Beatriz Lopomo
Rafael Oliveira Bergamo
Raquel Souza da Silva
Giovanna Vitória Consani Santos
Bruna Gomes Silva
Isabela Paulillo D’Onofrio
Henrique dos Santos

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1606615

3,728 views

Original Research

Published on 18 Jun 2025

The role of PRP in the healing of disc degeneration and the effect of local anesthetics on PRP

in Tissue Engineering and Regenerative Medicine

Ahmet Mert
Ayse Ikinci Keles
Murat Aydin
Huseyin Serkan Erol
Osman Fikret Sonmez

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1613148

1,767 views

Original Research

Published on 17 Jun 2025

Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model

in Tissue Engineering and Regenerative Medicine

Xiaoyang Yuan
Xulei Wang
Tianxi Du
Feng Zhang
Gang Cheng
Kang Wang
Haochen Xu
Pingting Yang
Yan Chang
Wei Wei

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1555983

2,255 views

Original Research

Published on 12 Jun 2025

Recombinant humanized collagen combined with nicotinamide increases the expression level of rat basement membrane proteins and promotes hair growth

in Tissue Engineering and Regenerative Medicine

Youshiqi Zhou
Boyu Chen
Shijia Ye
Haoyu Sun
Shuyue Wang
Xiaozhen Diao
Wenhui Wu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1546779

3,941 views

Review

Published on 12 Jun 2025

Pluripotency genes of mammals: a network at work

in Tissue Engineering and Regenerative Medicine

Ranieri Cancedda
Maddalena Mastrogiacomo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1578499

3,227 views

Original Research

Published on 03 Jun 2025

Strong, antioxidant, and biodegradable gelatin methacryloyl composite hydrogel for oxidative stress protection in Schwann cells

in Tissue Engineering and Regenerative Medicine

Hongyang Han
Dongcao Ji
Shu Yang
Bo Pang
Xi Chen
Jiaqi Zhu
Wenxin Cao
Tao Song

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1586380

2,774 views
3 citations

Original Research

Published on 30 May 2025

Subcutaneous injection of genetically engineered exosomes for androgenic alopecia treatment

in Tissue Engineering and Regenerative Medicine

Yukun Liu
Yonghong Liu
Jing Zhao
Tianyi Deng
Yinyin Ben
Ruitao Lu
Xusha Zhou
Runbin Yan
Xiaoqing Chen
Jian V. Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1614090

6,878 views
4 citations

Original Research

Published on 23 May 2025

hiPSC-derived cardiac fibroblasts dynamically enhance the mechanical function of hiPSC-derived cardiomyocytes on an engineered substrate

in Tissue Engineering and Regenerative Medicine

Mitchell Josvai
Jodi Lawson
Harshal Kanade
Meghana Kalluri
Corey L. Anderson
Jianhua Zhang
Alana Stempien
Lee L. Eckhardt
Timothy J. Kamp
Wendy C. Crone

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1546483

4,010 views
4 citations

Original Research

Published on 22 May 2025

Innate immune pathway activated mesenchymal stromal cells improve function and histologic outcomes in a rodent osteoarthritis model

in Tissue Engineering and Regenerative Medicine

Cody Plaisance
Lyndah Chow
Renata Impastato
Zoë J. Williams
Isabella Sabino
Katie J. Sikes
Kelly S. Santangelo
Steven Dow
Lynn M. Pezzanite

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1525969

2,826 views
2 citations

Original Research

Published on 21 May 2025

Clinical evaluation of computer-aided design and three-dimensional printing for completely edentulous mandibular custom tray fabrication: assessing clinician satisfaction

in Tissue Engineering and Regenerative Medicine

Tian Zhao
Yi Weng
Ning Li
Yiming Gao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1556651

2,173 views

Original Research

Published on 16 May 2025

Development of a procedure for isolation, identification and quality assessment of bovine spermatids and evaluation of their fertilizing ability in vitro

in Tissue Engineering and Regenerative Medicine

Rolando Pasquariello
Francesca Di Filippo
Sai Kamal Nag Bonumallu
Fernanda Fagali Franchi
Ramona Pistucci
Federica Franciosi
Valentina Lodde
Alessandra Iannuzzi
Alberto Maria Luciano
Tiziana A. L. Brevini

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1581019

2,884 views

Review

Published on 12 May 2025

Innovative hydrogels in cutaneous wound healing: current status and future perspectives

in Tissue Engineering and Regenerative Medicine

Prasad Sawadkar
Ferdinand Lali
Elena Garcia-Gareta
Beatriz Gil Garrido
Abdullah Chaudhry
Priya Matharu
Christos Kyriakidis
Karin Greco

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1454903

7,737 views
14 citations

Review

Published on 09 May 2025

Natural bioactive compounds modified with mesenchymal stem cells: new hope for regenerative medicine

in Tissue Engineering and Regenerative Medicine

Jingjing Wu
Ying Ge
Wendi Huang
Li Zhang
Juan Huang
Nanqu Huang
Yong Luo

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1446537

4,181 views
1 citation

Review

Published on 28 Apr 2025

Urine-derived stem cells: a sustainable resource for advancing personalized medicine and dental regeneration

in Tissue Engineering and Regenerative Medicine

Gamal A. Atia
Ahmed Abdal Dayem
Ehab S. Taher
Wafaa Y. Alghonemy
Ssang-Goo Cho
Ahmed A. Aldarmahi
Md Azizul Haque
Abeer Alshambky
Noha Taymour
Ateya M. Ibrahim

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1571066

7,905 views
6 citations

Original Research

Published on 25 Apr 2025

Comprehensive biocompatibility profiling of human pancreas-derived biomaterial

in Tissue Engineering and Regenerative Medicine

Amish Asthana
Amanda Gallego
Quentin Perrier
Tamara Lozano
Lori N. Byers
Jun Ho-Heo
Wonwoo Jeong
Riccardo Tamburrini
Arunkumar Rengaraj
Deborah Chaimov

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1518665

3,772 views
2 citations

Original Research

Published on 24 Apr 2025

PDGF-BB overexpressing dental pulp stem cells improve angiogenesis in dental pulp regeneration

in Tissue Engineering and Regenerative Medicine

Wentao Jiang
Shuhan Duan
Weiping Li
Huijiao Yan
Chenli Si
Ningwei Xu
Yishuai Li
Wenjie Zhang
Shensheng Gu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1578410

3,879 views
4 citations

Correction

Published on 24 Apr 2025

Corrigendum: Redefining vascular repair: revealing cellular responses on PEUU—gelatin electrospun vascular grafts for endothelialization and immune responses on in vitro models

in Tissue Engineering and Regenerative Medicine

María A. Rodríguez-Soto
Alejandra Riveros-Cortés
Ian C. Orjuela-Garzón
Inés María Fernández-Calderón
Cristian F. Rodríguez
Natalia Suárez Vargas
Carlos Ostos
Carolina Muñoz Camargo
Juan C. Cruz
Seungil Kim

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1607125

1,653 views

Review

Published on 14 Apr 2025

3D bioprinting for bile duct tissue engineering: current status and prospects

in Tissue Engineering and Regenerative Medicine

Bo Gao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1554226

3,570 views
3 citations

Perspective

Published on 14 Apr 2025

Transforming meat waste into sustainable corneal keratoplasty models

in Tissue Engineering and Regenerative Medicine

Ayman Mobin
Zayd Hashem
Peter R. Corridon

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1572127

1,829 views
1 citation

1,191 articles

articles

Biological effects of exosomes derived from 2D and 3D culture adipose stem cells on JEC Cell proliferation and migration

Olfactory mucosal mesenchymal stem cells delivered by gelatin sponge scaffolds promote functional recovery of spinal cord injury

3D visualization of uterus and ovary: tissue clearing techniques and biomedical applications

Low-intensity ultrasound lysis of amyloid microclots in a lab-on-chip model

Targeting osteoarthritis with small extracellular vesicle therapy: potential and perspectives

Acellular porcine placental membranes as a novel biomaterial for tissue repair applications

The role of PRP in the healing of disc degeneration and the effect of local anesthetics on PRP

Distribution and metabolism of iPSC-MSCs in the joint cavity of an osteoarthritis rat model

Recombinant humanized collagen combined with nicotinamide increases the expression level of rat basement membrane proteins and promotes hair growth

Pluripotency genes of mammals: a network at work

Strong, antioxidant, and biodegradable gelatin methacryloyl composite hydrogel for oxidative stress protection in Schwann cells

Subcutaneous injection of genetically engineered exosomes for androgenic alopecia treatment

hiPSC-derived cardiac fibroblasts dynamically enhance the mechanical function of hiPSC-derived cardiomyocytes on an engineered substrate

Innate immune pathway activated mesenchymal stromal cells improve function and histologic outcomes in a rodent osteoarthritis model

Clinical evaluation of computer-aided design and three-dimensional printing for completely edentulous mandibular custom tray fabrication: assessing clinician satisfaction

Development of a procedure for isolation, identification and quality assessment of bovine spermatids and evaluation of their fertilizing ability in vitro

Innovative hydrogels in cutaneous wound healing: current status and future perspectives

Natural bioactive compounds modified with mesenchymal stem cells: new hope for regenerative medicine

Urine-derived stem cells: a sustainable resource for advancing personalized medicine and dental regeneration

Comprehensive biocompatibility profiling of human pancreas-derived biomaterial

PDGF-BB overexpressing dental pulp stem cells improve angiogenesis in dental pulp regeneration

Corrigendum: Redefining vascular repair: revealing cellular responses on PEUU—gelatin electrospun vascular grafts for endothelialization and immune responses on in vitro models

3D bioprinting for bile duct tissue engineering: current status and prospects

Transforming meat waste into sustainable corneal keratoplasty models