Frontiers in Immunology | B Cell Biology

Original Research

Accepted on 21 Oct 2025

Mitogen-activated protein kinase pathway and four genes involved in the development of benign prostatic hyperplasia: in vivo and vitro validation

in B Cell Biology

GU JIAMIN
xingpei guo
Lan Wu
Lu-Yao Li
Tong Deng
shuangying wang
Xian-Tao Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1606607

Hypothesis and Theory

Accepted on 21 Oct 2025

Exuberant long noncoding RNA expression may sculpt Igh locus topology

in B Cell Biology

Ellen Brandenburg Drake
Sarah Naiyer
Xinyan Qu
Khalid Bhat
Hammad Farooq
Mark Maienschein-Cline
Jie Liang
Amy L Kenter

Frontiers in Immunology

doi 10.3389/fimmu.2025.1678105

Original Research

Published on 20 Oct 2025

CD39 is an antibody-secreting B-cell marker that modulates germinal center and antibody responses during infection

in B Cell Biology

Laura Almada
Yamila N. Gazzoni
Cristian G. Beccaria
Facundo Fiocca Vernengo
Santiago Boccardo
Melisa Gorosito Serrán
Apurwa Trivedi
Carola G. Vinuesa
Simon C. Robson
Eva V. Acosta Rodríguez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547929

903 views

Original Research

Published on 17 Oct 2025

Pediatric B cell repertoires are enriched for naive clonal phenotypes and are shaped by distinct selection dynamics

in B Cell Biology

Thomas Hsiao
Areen Shtewe
Uri Hershberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1618234

1,426 views

Original Research

Published on 16 Oct 2025

B cell subpopulations and their role in the pathogenesis of primary Sjögren’s syndrome: insights from single-cell RNA sequencing

in B Cell Biology

Xiaoyu Zhang
Yuanwei Han
Jing Zhang
Yu Song
Yan Zhou
Jia Wang
Jinhai Tian
Xinran Xin
Bin Liu
Li Fang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665086

1,691 views

Mini Review

Accepted on 15 Oct 2025

The Dual Immunomodulatory Role of B Cells in Tumorigenesis: Mechanisms, Microenvironment Crosstalk, and Therapeutic Implications

in B Cell Biology

Lv Zhuangwei
Ruohao Yang
Kai Zhang
Ruihan Wang
Xiaoyu Shi
Jinhua Wu
Lulu Liu
Junna Jiao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649812

163 views

Original Research

Published on 15 Oct 2025

Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis

in B Cell Biology

Xuan Wu
Wei Chen
Huanhuan Song
Guorong Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667799

1,516 views

Original Research

Published on 14 Oct 2025

Agglutinin chip screening of B cell surface biomarkers in Hashimoto’s thyroiditis for therapeutic targeting

in B Cell Biology

Jun-ling Ren
Xiao-ming Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636003

1,745 views

Original Research

Published on 13 Oct 2025

Directed evolution of drug-like Aβ conformation-specific antibodies

in B Cell Biology

Alec A. Desai
Matthew D. Smith
Jennifer M. Zupancic
Emily K. Makowski
Yulei Zhang
Julia E. Gerson
Shannon J. Moore
Alexandra B. Sutter
Sean P. Ferris
Magdalena I. Ivanova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655893

701 views

Original Research

Accepted on 10 Oct 2025

B cell receptor repertoire reconstitution in patients with neuromyelitis optica spectrum disorder receiving B-cell depletion therapy

in B Cell Biology

Hyo Jae Kim
Wangyong Shin
Dayoung Seo
Inhye Jang
Jihong Ryu
Lynkyung Choi
Jinhee Kim
Hyunjin Kim
Young-Min Lim
Eun-Jae LEE

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673508

515 views

Original Research

Published on 08 Oct 2025

Bexarotene signaling in human B and T lymphocytes induces gut-homing receptor expression

in B Cell Biology

Sina Kaiser
Ina Suhrkamp
Jinru He
Charlotte Helf
Christian D. Sadik
Michael Weichenthal
Guido Heine

Frontiers in Immunology

doi 10.3389/fimmu.2025.1664199

1,748 views

Review

Published on 02 Oct 2025

Immunoglobulin: unraveling its complex web in aging

in B Cell Biology

Qiaoli Gu
Yi Wang
Can Zhu
Xichao Zhou
Li Ni
Huan Zhao
Huilin Yang
Qin Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690018

2,654 views

Mini Review

Published on 29 Sep 2025

Developmental trajectory of long-lived plasma cells

in B Cell Biology

Takuya Koike
Wataru Ise

Frontiers in Immunology

doi 10.3389/fimmu.2025.1684210

2,989 views

Mini Review

Published on 25 Sep 2025

The half-century odyssey of regulatory B cells: from Breg discovery to emerging frontiers

in B Cell Biology

Elina A. Zheremyan
Nikolai R. Kon
Alina S. Ustiugova
Ekaterina M. Stasevich
Elvina A. Bogomolova
Matvey M. Murashko
Aksinya N. Uvarova
Denis E. Demin
Dmitry V. Kuprash
Kirill V. Korneev

Frontiers in Immunology

doi 10.3389/fimmu.2025.1681082

2,654 views

Original Research

Published on 22 Sep 2025

Toll-like receptor 7/8 agonist stimulation rapidly skews the antibody repertoire of B cells in non-human primates

in B Cell Biology

Shiyu Wang
Michael Citron
Lihua Luo
I-Ming Wang
Xiao Liu
Wei Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647209

2,579 views

Original Research

Published on 10 Sep 2025

YBX1 modulates humoral immunity through post-transcriptional regulation in B cells

in B Cell Biology

Viktoria Kunz
Kathryn S. Bommert
Ralf Bargou
Kurt Bommert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653073

2,117 views