Frontiers in Immunology | B Cell Biology

Original Research

Published on 02 Sep 2025

Maturation of human early-minted blood antibody-secreting cells is coupled with increased IgG secretion rates

in B Cell Biology

Doan C. Nguyen
Ian T. Hentenaar
Monica Cabrera-Mora
Shuya Kyu
Andrea Morrison-Porter
Natalie S. Haddad
Joel Andrews
Danielle Roberts
Sagar Lonial
Ignacio Sanz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644102

6,367 views

Original Research

Accepted on 28 Aug 2025

Toll-like receptor 7/8 agonist stimulation rapidly skews the antibody repertoire of B cells in non-human primates

in B Cell Biology

Shiyu Wang
Yifei Wu
Yuting Xu
Rui Deng
Fangzheng Liu
Michael Citron
Lihua Luo
I-Ming Wang
Xiao Liu
Wei Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647209

558 views

Editorial

Published on 28 Aug 2025

Editorial: B-cell deficiency and infection: exploring humoral immunity’s protective mechanisms

in B Cell Biology

Alexandros Grammatikos
Peter Bergman

Frontiers in Immunology

doi 10.3389/fimmu.2025.1678416

854 views

Original Research

Published on 25 Aug 2025

Engrafted NSG-SGM3 humanized mice spontaneously produce human immunoglobulins including IgE

in B Cell Biology

Erica V. Lin
Rebecca A. Krier-Burris
Kristina A. Sokol
Betania Arce
Natalia M. Vilela
Robert G. Hamilton
Bruce S. Bochner
Melanie C. Dispenza

Frontiers in Immunology

doi 10.3389/fimmu.2025.1628194

1,207 views

Original Research

Published on 21 Aug 2025

Conventional and non-conventional antigen-binding sites promote the development and function of chronic lymphocytic leukemia stereotyped subset #4 clones

in B Cell Biology

Yun Liu
Dzmitry Padhorny
Rosa Catera
Antonella Nicolo
Xiao-Jie Yan
Stan Xiaogang Li
Anastasia Iatrou
Andrea N. Mazzarello
Noemi Destefani
Steven L. Allen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607189

1,182 views

Case Report

Published on 21 Aug 2025

Obinutuzumab-induced severe acute thrombocytopenia: a case report and literature review

in B Cell Biology

Kun Kou
Qiaolin Zhou
Lijun Du
Fang Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609862

712 views

Original Research

Accepted on 18 Aug 2025

Directed evolution of drug-like Aβ conformation-specific antibodies

in B Cell Biology

Alec A Desai
Matt D Smith
Jennifer M Zupancic
Emily K Makowski
Yulei Zhang
Julia E Gerson
Shannon J Moore
Alexandra Sutter
Sean P Ferris
Magdalena Ivanova

Frontiers in Immunology

doi 10.3389/fimmu.2025.1655893

234 views

Review

Published on 18 Aug 2025

B cell depletion as a therapeutic strategy for neuromyelitis optica spectrum disorder: rationale, evidence, and challenges

in B Cell Biology

Hirofumi Ochi
Satoru Nakamura
Jin Nakahara

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635989

1,041 views

Original Research

Published on 15 Aug 2025

Comparative analysis of CDR3 length-dependent patterns in VHHs

in B Cell Biology

Lu Zhang
Tianyu Yang
Yao Zhang
Jiahui Yan
Jiaguo Li
Wenfeng Xu
Weimin Zhu
Xinhao Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1647230

837 views

Original Research

Accepted on 14 Aug 2025

RUNX1 Expression Dynamics in Plasma Cell Differentiation and Pathogenesis of Multiple Myeloma

in B Cell Biology

Ting Fang Tang
YEE TENG CHAN
Hui Jing Lim
Nur Adila Anuar
Chin Sum Cheong
Chung Yeng Looi
Sen Mui Tan
Won Fen Wong
Gin Gin Gan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1643615

247 views

Editorial

Published on 13 Aug 2025

Editorial: Unraveling mechanisms and implications of anti-RBC antibodies in transfusion medicine

in B Cell Biology

Krystalyn E. Hudson
David R. Gibb

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671343

574 views

Original Research

Accepted on 11 Aug 2025

Tenascin-C regulates CXCR4⁺ B cell migration and cortex formation in the developing bursa of Fabricius

in B Cell Biology

Ádám Soós
Emőke Szőcs
Viktória Halasy
Nándor Nagy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1636140

135 views

Review

Published on 08 Aug 2025

B cell development: transcriptional regulation and immunological mechanisms in homeostasis

in B Cell Biology

Jorge Gómez-Manríquez
Jorge Hernández-Bello
José Francisco Muñoz-Valle
Sonia Sifuentes-Franco
Omar Graciano-Machuca
José Javier Morales-Núñez

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593338

1,076 views

Review

Published on 07 Aug 2025

The role of B lymphocyte subsets in nephrotic syndrome: functions, mechanisms, clinical significance and future perspectives

in B Cell Biology

Yuheng Liao
Haofei Hu
Qijun Wan
Haiying Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598197

1,152 views

Original Research

Published on 06 Aug 2025

Investigation into the prognostic factors of early recurrence and progression in previously untreated diffuse large B-cell lymphoma and a statistical prediction model for POD12

in B Cell Biology

Ke Lian
Wenyao Zhu
Zhihui Hu
Fang Su
CaiXia Xu
Hui Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1539924

705 views

Original Research

Published on 01 Aug 2025

Clone-specific residue changes at multiple positions are associated with amyloid formation by antibody light chains

in B Cell Biology

Gareth J. Morgan
Tatiana Prokaeva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1622207

664 views