Frontiers in Immunology | Cytokines and Soluble Mediators in Immunity

Review

Published on 10 Jul 2025

Mechanistic insights into Nrf2-driven pathogenesis and therapeutic targeting in spinal cord injury

in Cytokines and Soluble Mediators in Immunity

Tao Xie
Jiyu Xu
Xinyu Liu
Yaquan Yu
Yang Lu
Tao Wang
Feng Gao
Hui Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574834

151 views

Original Research

Accepted on 08 Jul 2025

Impact of High Hydrostatic Pressure on the Cytokine Profile and Head and Neck Cancer Cell Behavior: Implications for Oncological Safety

in Cytokines and Soluble Mediators in Immunity

Julia Kristin Brach
Vivica Freiin Grote
Daniel Strüder
Friederike Kalle
Anika Jonitz-Heincke
Rainer Bader
Marco Hoffmann
Agmal Scherzad
Markus Wirth
Stephan Hackenberg

Frontiers in Immunology

doi 10.3389/fimmu.2025.1581014

Mini Review

Published on 08 Jul 2025

Dichotomous roles of IL-36 and IL-38 in cardiovascular disease

in Cytokines and Soluble Mediators in Immunity

Haifeng Zhang
Wenhui Huang
Shisan Bao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642116

227 views

Original Research

Published on 07 Jul 2025

Microglial clock dysfunction during neuroinflammation impairs oligodendrocyte progenitor cell recruitment and disrupts neuroimmune homeostasis

in Cytokines and Soluble Mediators in Immunity

Qingqing Lu
Jin Young Kim

Frontiers in Immunology

doi 10.3389/fimmu.2025.1620343

308 views

Editorial

Accepted on 02 Jul 2025

Editorial: Organ crosstalk and other responses to an activated immune system in trauma and disease

in Cytokines and Soluble Mediators in Immunity

Martijn van Griensven
Elizabeth R Balmayor
Frank Hildebrand

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651022

Review

Accepted on 30 Jun 2025

Inflammation-Associated Drug Resistance and Tumor Growth in TNBC

in Cytokines and Soluble Mediators in Immunity

Arij Fouzat Hassan
Hadeel Kheraldine
Hamda Al-Thawadi
Abdelbary Elhissi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623137

121 views

Original Research

Accepted on 30 Jun 2025

Evaluation of the levels of interleukins IL-4, IL-13, IL-5, IL-10 and IL-33 in atopic dermatitis patients with and without dupilumab therapy

in Cytokines and Soluble Mediators in Immunity

Jarmila Celakovska
Eva Cermakova
Petra Boudkova
Jan Krejsek

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604883

Original Research

Published on 30 Jun 2025

An assembled molecular signaling map of interleukin-24: a resource to decipher its multifunctional immunoregulatory role in pathophysiological conditions

in Cytokines and Soluble Mediators in Immunity

Anjana Aravind
Vineetha Shaji
Mukhtar Ahmed
Shobha Dagamajalu
Manavalan Vijayakumar
Thottethodi Subrahmanya Keshava Prasad
Rajesh Raju

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608101

446 views

Review

Published on 30 Jun 2025

Astrocyte–microglia crosstalk in subarachnoid hemorrhage: mechanisms and treatments

in Cytokines and Soluble Mediators in Immunity

Kaibo Yu
Ding Wang
Wenhua Yu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1547858

383 views

Original Research

Accepted on 27 Jun 2025

Metrnl/Meteorin-like/IL-41, a Novel Regulator of Bone Metabolism and Disease Activity in Ankylosing Spondylitis: Based on Multi-omics Analysis

in Cytokines and Soluble Mediators in Immunity

Zhuoqi Li
Sun Tao
Min Zhao
Liping Xia
Hui Shen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595181

131 views

Mini Review

Published on 27 Jun 2025

Hidradenitis suppurativa and daily lifestyle

in Cytokines and Soluble Mediators in Immunity

Natsuko Saito-Sasaki
Yu Sawada

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627638

386 views

Mini Review

Published on 26 Jun 2025

Extracellular vesicles: molecular messengers and new therapeutic targets in acute myocardial infarction

in Cytokines and Soluble Mediators in Immunity

Hao Wu
Jinyi Xue
Qiuyu Liu
Zhenxun Wan
Lingling Liang
Shihan Sun
Ping Liu
Mingtai Chen
Mengnan Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598407

404 views

Original Research

Published on 26 Jun 2025

IL-36/IL-36R signaling promotes CD4+ T cell-dependent colitis via pro-inflammatory cytokine production

in Cytokines and Soluble Mediators in Immunity

Maya Maarouf
Michal Kuczma
Timothy L. Denning

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604332

359 views

Original Research

Published on 26 Jun 2025

Relationship between peripheral blood miR-146b-5p levels and lymphocyte subsets in patients with sepsis and its predictive value for prognosis: a single-center study

in Cytokines and Soluble Mediators in Immunity

Sha Cheng
Jiaojiao Wang
Pengfei Wang
Xianli Long
Huiling Liu
Xueyin Li
Xiaowei Zhang
Xuemei Zhao
Hang Sun
Chuanxin Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1608576

280 views

Original Research

Published on 24 Jun 2025

Comprehensive immune profiling and predictive modelling of paediatric acute hepatitis of unknown aetiology from a Spanish cohort

in Cytokines and Soluble Mediators in Immunity

Roberto Lozano-Rodríguez
Loreto Hierro
María José Quiles
Alejandro Pascual-Iglesias
Verónica Terrón-Arcos
Gema Muñoz-Bartolo
Esteban Frauca
Francisco J. Cueto
Cristina Calvo
Laura Córdoba-García

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599982

1,019 views

Original Research

Accepted on 23 Jun 2025

Targeting the major pro-inflammatory Interleukin-6-type cytokine receptor gp130 by antagonistic single domain antibodies

in Cytokines and Soluble Mediators in Immunity

Silke Pudewell
Julia Heuser
Inna Dorogobed
Britta Lipinski
Thi Hong Hue Tran
Pia Metzenmacher
Richard Kunze
Felix Geyer
Stefan Zielonka
Doreen Floss

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613004

154 views