Frontiers in Immunology

Original Research

Published on 05 Sep 2025

Mesenchymal stem cells enhanced with SeNPs protection against CLP induction associated with liver injury are mediated via antioxidant, anti-inflammatory, and immunomodulatory activities

in Inflammation

Asmaa M. M. Abd El Aleem
Manal F. El-Khadragy
Ahmed E. Abdel Moneim
Sara H. Agwa
Fatma Abou Zahra
Mohga S. Abdalla

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602994

3,763 views
2 citations

Original Research

Published on 05 Sep 2025

Identifying pyroptosis-hub genes and immune infiltration in neonatal hypoxic-ischemic brain injury

in Inflammation

Chi Qin
Yue Li
Meiying Cheng
Huixian Li
Ronghao Mu
Jian Jin
Bohao Zhang
Xin Zhao
Xiaoan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616312

3,962 views

Original Research

Published on 05 Sep 2025

Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis

in Inflammation

Erli Wu
Qiangqiang Zhuo
Xuan Yin
Jingjing Li
Huijuan Zhang
Feihan Gu
Feng Liang
Xianqing Zhou
Ziyang Gao
Bang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1671919

3,202 views

Mini Review

Published on 05 Sep 2025

Inflammatory mechanisms and therapeutic advances in chronic endometritis

in Inflammation

Xinyang Yan
Jiao Jiao
Xiuxia Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616217

4,915 views
3 citations

Review

Published on 04 Sep 2025

Exosomes and non-coding RNAs in the regulation of neuroinflammation after ischemic stroke: mechanisms and therapeutic perspectives

in Inflammation

Dekai Wei
Fujun Li
Chunhui Guo
Jibing Chen
Yanqiu You

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601843

4,726 views

Mini Review

Published on 04 Sep 2025

Roles of exosomes in immune regulation of osteoarthritis and their applications in inflammation repair

in Inflammation

Shuquan Lan
Chao Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1611718

3,793 views

Review

Published on 04 Sep 2025

Macrophage heterogeneity in liver fibrosis

in Inflammation

Wenzhao Wang
Shengwen Li
Yanjun Liu
Xin Ding
Yongqi Yang
Shiyun Chen
Jiafan Cao
Frank Tacke
Wei Dong
Tian Lan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1639455

5,436 views
2 citations

Original Research

Published on 04 Sep 2025

Myeloid-specific S100A8/A9 deficiency attenuates atrial fibrillation through prevention of TLR4/NF-kB-mediated immune cell recruitment and inflammation

in Inflammation

Qing Wang
Hua Shen
Jing Wang
Guifang Wang
Yufeng Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1623486

3,228 views
3 citations

Original Research

Published on 04 Sep 2025

Structural modifications to pregnane neurosteroids alter inhibition of LPS/Lipid A binding at the MD-2 activation site within the TLR4 signaling complex

in Inflammation

Alejandro G. Lopez
Venkat R. Chirasani
Irina Balan
A. Leslie Morrow

Frontiers in Immunology

doi 10.3389/fimmu.2025.1632891

2,014 views
2 citations

Original Research

Published on 03 Sep 2025

Golexanolone affords sustained microglia and astrocytes activation improvement in a rat model of Parkinson’s disease

in Inflammation

Gergana Mincheva
Maria A. Pedrosa
Mar Martínez-García Vázquez
Lola Vazquez
Thomas P. Blackburn
Magnus Doverskog
Marta Llansola
Vicente Felipo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654664

3,475 views
1 citation

Original Research

Published on 03 Sep 2025

Diagnostic lncRNA biomarkers and immune-related ceRNA networks for osteonecrosis of the femoral head in metabolic syndrome identified by plasma RNA sequencing and machine learning

in Inflammation

Haoyan Sun
Meng Xu
Dianlong Mi
Qingyu Li
Haipeng Sun
Yang Song

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640657

4,043 views

Review

Published on 03 Sep 2025

Ferroptosis in pain: evidence, challenges, and opportunities

in Inflammation

Qianqian Yan
Fang Wang
Mengyuan Liu
Jinyan Mao
Zihao Zhao
Bo Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673783

3,440 views

Systematic Review

Published on 03 Sep 2025

A meta-analysis of chemokines in alopecia areata: recruiting immune cells toward the hair follicle

in Inflammation

Elise Van Caelenberg
Arno Belpaire
Nanja van Geel
Reinhart Speeckaert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648868

3,819 views
1 citation

Original Research

Published on 03 Sep 2025

Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis

in Inflammation

Dongli Cao
Huashun Cui
Zequan Chen
Heyang Li
Bing Li
Jianhua Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629226

2,898 views
1 citation

Original Research

Published on 03 Sep 2025

Zinc alleviates stroke development through autophagy-mediated modulation of immune microenvironment

in Inflammation

Zijie Qiu
Xin Liu
Jie Li
Hongming Yin
Jiankun Luo
Zigang Lin
Mayire Rexiati
Adila Abulaiti
Aikebaier Yasen
Lifei Xing

Frontiers in Immunology

doi 10.3389/fimmu.2025.1666225

3,261 views

Original Research

Published on 03 Sep 2025

Polystyrene nanoplastics induce oxidative stress in Aurelia coerulea polyps, microglia, and mice

in Inflammation

Mingshuai Song
Zhenyu Wei
Jingqiang Wang
Liangzhi Li
Xiangyu Li
Xiaofen Ma
Marina Pozzolini
Xinyan Liu
Liang Xiao
Ping Zhong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609208

2,829 views
1 citation

Original Research

Published on 03 Sep 2025

Changes in monocyte subsets are associated with an increased risk of AAA and are surrogate markers for AAA morphology in patients with late-stage disease

in Inflammation

Bianca Hamann
Anna Klimova
Marvin Kapalla
David M. Poitz
Albert Busch
Henning Morawietz
Christian Reeps
Anja Hofmann

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621888

1,778 views
2 citations

Perspective

Published on 02 Sep 2025

Inflammation preservation strategy: reconciling pain control and disc resorption in lumbar disc herniation

in Inflammation

Guanyi Gong
Zheng Yan
Qilong Lai
Peijie You
Pengfei Yu
Xiaochun Li
Zhiqiang Wang
Shun Lin
Yuxiang Dai
Hong Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1653681

5,415 views
1 citation

Review

Published on 02 Sep 2025

Postoperative adhesion formation: the role of peritoneal macrophages and targeting therapy

in Inflammation

Zhong-Yuan Liu
Ren-Feng Li
Hong-Yan Qin
Peng-Fei Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1601642

3,991 views

Original Research

Published on 02 Sep 2025

The role of neutrophils and NETosis in lipopolysaccharide exacerbated asthmatic airway inflammation

in Inflammation

Qian Qian
Qianye Zhao
Yongji Qian
Huan Deng
Xiaoming Feng
Jiamin Zhang
Xia Huang
Yi Du
Deyu Zhao
Feng Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1651085

2,938 views

Review

Published on 01 Sep 2025

From mechanisms to therapies: current advances breakthroughs in alopecia areata immunopathology

in Inflammation

Huai-Bo Zhao
Ya-Nan Zhang
Yan Qiang
Guo-Mi Wang
Li-Wei Wang
Wen-Cheng Jiang
Xi Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621492

7,298 views
3 citations

Review

Published on 01 Sep 2025

Protein palmitoylation: an emerging regulator of inflammatory signaling and diseases

in Inflammation

Rong Chen
Xiaohua Tang
Ying Wang
Bo Wang
Fei Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652741

5,531 views
1 citation

Review

Published on 01 Sep 2025

NLRP3 and beyond: inflammasomes as central cellular hub and emerging therapeutic target in inflammation and disease

in Inflammation

María Virginia Pinzón-Fernández
Jhan S. Saavedra-Torres
Nelson Adolfo López Garzón
Jessica S. Pachon-Bueno
Francisco Javier Tamayo-Giraldo
María Camila Rojas Gomez
Marlon Arias-Intriago
Alice Gaibor-Pazmiño
Andrés López-Cortés
Juan S. Izquierdo-Condoy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1624770

8,909 views
16 citations

Review

Published on 29 Aug 2025

Cyclophilin D (PPIF) and MPTP in hepatic ischemia-reperfusion injury: insights into mechanisms

in Inflammation

Jingxin Liu
Chengyu Wu
Ziyun Lin
Maomao Ma
Wei Ma
Xuefeng Yu
Kai Wang
Bin Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575242

3,021 views
1 citation

5,790 articles

articles

Mesenchymal stem cells enhanced with SeNPs protection against CLP induction associated with liver injury are mediated via antioxidant, anti-inflammatory, and immunomodulatory activities

Identifying pyroptosis-hub genes and immune infiltration in neonatal hypoxic-ischemic brain injury

Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis

Inflammatory mechanisms and therapeutic advances in chronic endometritis

Exosomes and non-coding RNAs in the regulation of neuroinflammation after ischemic stroke: mechanisms and therapeutic perspectives

Roles of exosomes in immune regulation of osteoarthritis and their applications in inflammation repair

Macrophage heterogeneity in liver fibrosis

Myeloid-specific S100A8/A9 deficiency attenuates atrial fibrillation through prevention of TLR4/NF-kB-mediated immune cell recruitment and inflammation

Structural modifications to pregnane neurosteroids alter inhibition of LPS/Lipid A binding at the MD-2 activation site within the TLR4 signaling complex

Golexanolone affords sustained microglia and astrocytes activation improvement in a rat model of Parkinson’s disease

Diagnostic lncRNA biomarkers and immune-related ceRNA networks for osteonecrosis of the femoral head in metabolic syndrome identified by plasma RNA sequencing and machine learning

Ferroptosis in pain: evidence, challenges, and opportunities

A meta-analysis of chemokines in alopecia areata: recruiting immune cells toward the hair follicle

Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis

Zinc alleviates stroke development through autophagy-mediated modulation of immune microenvironment

Polystyrene nanoplastics induce oxidative stress in Aurelia coerulea polyps, microglia, and mice

Changes in monocyte subsets are associated with an increased risk of AAA and are surrogate markers for AAA morphology in patients with late-stage disease

Inflammation preservation strategy: reconciling pain control and disc resorption in lumbar disc herniation

Postoperative adhesion formation: the role of peritoneal macrophages and targeting therapy

The role of neutrophils and NETosis in lipopolysaccharide exacerbated asthmatic airway inflammation

From mechanisms to therapies: current advances breakthroughs in alopecia areata immunopathology

Protein palmitoylation: an emerging regulator of inflammatory signaling and diseases

NLRP3 and beyond: inflammasomes as central cellular hub and emerging therapeutic target in inflammation and disease

Cyclophilin D (PPIF) and MPTP in hepatic ischemia-reperfusion injury: insights into mechanisms