Frontiers in Immunology

Original Research

Published on 19 Jun 2025

A novel, rapid, and practical prognostic model for sepsis patients based on dysregulated immune cell lactylation

in Inflammation

Chang Li
Mei He
PeiChi Shi
Lu Yao
XiangZhi Fang
XueFeng Li
QiLan Li
XiaoBo Yang
JiQian Xu
You Shang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625311

4,752 views
3 citations

Original Research

Published on 19 Jun 2025

Single-cell atlas of human skin implicates APOE pro-inflammatory signaling in diabetic foot ulcers

in Inflammation

Yating Yin
Li Li
Mingen Liu
Bin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591944

3,938 views
2 citations

Review

Published on 19 Jun 2025

Thromboinflammation vs. immunothrombosis: strategies for overcoming anticoagulant resistance in COVID-19 and other hyperinflammatory diseases. Is ROTEM helpful or not?

in Inflammation

Lou M. Almskog
Anna Ågren

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599639

4,913 views
8 citations

Mini Review

Published on 18 Jun 2025

Harnessing extracellular vesicles to tame inflammation: a new strategy for atherosclerosis therapy

in Inflammation

Jiawei Li
Tianliang Wen
Xiaoran Li
Ruoyao Cheng
Junyi Shen
Xin Wang
Zhaoqi Guo
Zhengjie Teng
Lin Yi
Fan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1625958

4,438 views
3 citations

Case Report

Published on 18 Jun 2025

Complete recovery after complement factor I deficiency associated fulminant acute hemorrhagic leukoencephalitis: a case report

in Inflammation

Fanni Szumutku
Léna Szabó
Zoltán Liptai
Edit Varga
Tímea Seszták
Péter Barsi
Ádám Goschler
Gábor Szarvas
Klára Horváth
Simon Péter Nagy

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586288

2,802 views

Hypothesis and Theory

Published on 18 Jun 2025

Interplay of trauma-triggered auto-inflammation and T-cell auto-reactivity in posttraumatic dystrophy

in Inflammation

Egmont Scola

Frontiers in Immunology

doi 10.3389/fimmu.2025.1404161

2,230 views

Mini Review

Published on 18 Jun 2025

Decoding neuroinflammation in Alzheimer’s disease: a multi-omics and AI-driven perspective for precision medicine

in Inflammation

Shiyu Lin
Yijun Zhan
Ruiqi Wang
Jian Pei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616899

7,476 views
5 citations

Review

Published on 18 Jun 2025

Revisiting pulmonary fibrosis: inflammatory dynamics of the lipofibroblast-to-inflammatory lipofibroblast-to-activated myofibroblast reversible switch

in Inflammation

Georgios-Dimitrios Panagiotidis
Esmeralda Vasquez-Pacheco
Xuran Chu
Werner Seeger
Elie El Agha
Saverio Bellusci
Arun Lingampally

Frontiers in Immunology

doi 10.3389/fimmu.2025.1609509

7,284 views
5 citations

Mini Review

Published on 18 Jun 2025

Role of macrophages in neuroimmune regulation

in Inflammation

Hairong Xiao
Kai Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573174

4,175 views
3 citations

Original Research

Published on 18 Jun 2025

Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3

in Inflammation

Jian Song
Xinhua Huang
Yi Luo
Mengjun Li
Yulin Ouyang
Wanli Liu
Hudan Pan
Huanhuan Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563602

2,638 views

Original Research

Published on 18 Jun 2025

Modulation of glucocorticoid receptor function under iron overload

in Inflammation

Wanting Zhu
Tineke Vanderhaeghen
Steven Timmermans
Jolien Vandewalle
Melanie Eggermont
Nicolette J. D. Verhoog
Claude Libert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605420

2,432 views

Original Research

Published on 17 Jun 2025

Highly differentiated T cells link systemic and vascular inflammation in a mouse model of recurrent psoriasis

in Inflammation

Fabio Casciano
Paolo Severi
Laura Marongiu
Anna Caproni
Chiara Terranova
Alex Spitilli
Davide Ferrari
Chiara Ruzza
Peggy Marconi
Paola Rizzo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574455

4,215 views
4 citations

Original Research

Published on 17 Jun 2025

Phleum pratense pollen-derived di-galactosyldiacylglycerols promote pro-allergic responses in mice

in Inflammation

Nestor González Roldán
Lars P. Lunding
Yukari Fujimoto
Sylvia Düpow
Dominik Schwudke
Michael Wegmann
Katarzyna A. Duda

Frontiers in Immunology

doi 10.3389/fimmu.2025.1532773

2,976 views

Review

Published on 17 Jun 2025

Bile acid receptors regulate the role of intestinal macrophages in inflammatory bowel disease

in Inflammation

Hongjie Yang
Xianhong Shi
Beibei Wang
Heng Li
Bin Li
Tianqi Zhou
Lulu Tian
Shengjun Wang
Kai Yin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1577000

3,930 views
2 citations

Systematic Review

Published on 17 Jun 2025

Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis

in Inflammation

Yong Tian
Jiaqi Yao
Yihan Ma
Pengcheng Zhang
Xiaofang Zhou
Wenjie Xie
Wenfu Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571456

6,574 views
1 citation

Mini Review

Published on 17 Jun 2025

Incidental findings related to genes associated to HAE-nC1INH: how to proceed?

in Inflammation

Anastasios E. Germenis
Despina Sanoudou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605727

2,231 views
1 citation

Review

Published on 16 Jun 2025

The role of T-helper and T regulatory cells in driving neutrophilic and eosinophilic inflammation in bronchiectasis

in Inflammation

Evangelia Fouka
Anders Lindén
Apostolos Bossios

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598257

7,837 views
2 citations

Review

Published on 16 Jun 2025

Targeting oxidative stress in diabetic retinopathy: mechanisms, pathology, and novel treatment approaches

in Inflammation

Wei He
Panli Tang
Hongbin Lv

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571576

7,166 views
17 citations

Review

Published on 16 Jun 2025

The emerging role of cuproptosis in spinal cord injury

in Inflammation

Daoran Xu
Liyu Hu
Jinming Zhou
Xiongwei Deng
Yunrong Zhu
Chao Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595852

4,511 views

Original Research

Published on 16 Jun 2025

Integrated multi-omics and machine learning reveals immune-metabolic signatures in osteoarthritis: from bulk RNA-seq to single-cell resolution

in Inflammation

Hui He
Xiumei Zhao
Bo Zhang
Shijian Zhao
Yinteng Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1599930

5,084 views
5 citations

Original Research

Published on 16 Jun 2025

ScRNA-seq combined with ATAC-seq analysis to explore the metabolic balance mechanism of CCl4-induced liver inflammatory injury

in Inflammation

Hui Liu
Yisha Zhang
Shoubin Ning

Frontiers in Immunology

doi 10.3389/fimmu.2025.1600685

4,611 views

Editorial

Published on 12 Jun 2025

Editorial: Community series in inflammation in respiratory and neurological diseases and the immune-interaction of the lung-brain axis, volume II

in Inflammation

Yuyan Liu
Caicai Zhang
Wenhui Wu
Xuejing Wang
Ping Yuan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634921

1,818 views

Original Research

Published on 11 Jun 2025

Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 ameliorate barrier dysfunction in human induced pluripotent stem cell-derived crypt-villus structural small intestine

in Inflammation

Kyosuke Kobayashi
Yuri Imai
Yuka Shimizu
Isamu Ogawa
Takaaki Nakai
Yuri Mizuno
Yoshika Kaneda
Yumiko Watanabe-Yasuoka
Fuka Yamazaki
Junko Mochizuki

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585007

3,623 views

Original Research

Published on 11 Jun 2025

A novel molecule targeting neutrophil-mediated B-1a cell trogocytosis attenuates sepsis-induced acute lung injury

in Inflammation

Yuichi Akama
Jespar Chen
Alok Jha
Yongchan Lee
Gaifeng Ma
Jingsong Li
Atsushi Murao
Ping Wang
Monowar Aziz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597887

3,342 views
3 citations

5,790 articles

articles

A novel, rapid, and practical prognostic model for sepsis patients based on dysregulated immune cell lactylation

Single-cell atlas of human skin implicates APOE pro-inflammatory signaling in diabetic foot ulcers

Thromboinflammation vs. immunothrombosis: strategies for overcoming anticoagulant resistance in COVID-19 and other hyperinflammatory diseases. Is ROTEM helpful or not?

Harnessing extracellular vesicles to tame inflammation: a new strategy for atherosclerosis therapy

Complete recovery after complement factor I deficiency associated fulminant acute hemorrhagic leukoencephalitis: a case report

Interplay of trauma-triggered auto-inflammation and T-cell auto-reactivity in posttraumatic dystrophy

Decoding neuroinflammation in Alzheimer’s disease: a multi-omics and AI-driven perspective for precision medicine

Revisiting pulmonary fibrosis: inflammatory dynamics of the lipofibroblast-to-inflammatory lipofibroblast-to-activated myofibroblast reversible switch

Role of macrophages in neuroimmune regulation

Short-term exposure to a high-humidity environment triggers intestinal inflammation via AQP3

Modulation of glucocorticoid receptor function under iron overload

Highly differentiated T cells link systemic and vascular inflammation in a mouse model of recurrent psoriasis

Phleum pratense pollen-derived di-galactosyldiacylglycerols promote pro-allergic responses in mice

Bile acid receptors regulate the role of intestinal macrophages in inflammatory bowel disease

Thymosin alpha 1 alleviates inflammation and prevents infection in patients with severe acute pancreatitis through immune regulation: a systematic review and meta-analysis

Incidental findings related to genes associated to HAE-nC1INH: how to proceed?

The role of T-helper and T regulatory cells in driving neutrophilic and eosinophilic inflammation in bronchiectasis

Targeting oxidative stress in diabetic retinopathy: mechanisms, pathology, and novel treatment approaches

The emerging role of cuproptosis in spinal cord injury

Integrated multi-omics and machine learning reveals immune-metabolic signatures in osteoarthritis: from bulk RNA-seq to single-cell resolution

ScRNA-seq combined with ATAC-seq analysis to explore the metabolic balance mechanism of CCl4-induced liver inflammatory injury

Editorial: Community series in inflammation in respiratory and neurological diseases and the immune-interaction of the lung-brain axis, volume II

Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 ameliorate barrier dysfunction in human induced pluripotent stem cell-derived crypt-villus structural small intestine

A novel molecule targeting neutrophil-mediated B-1a cell trogocytosis attenuates sepsis-induced acute lung injury