Frontiers in Immunology

Original Research

Published on 20 May 2025

Single-cell RNA sequencing identifies two fibroblast subtypes and a Trem2+ macrophage subtype as the possible specific cellular targets in abdominal aortic aneurysms

in Inflammation

Zhili Liu
Xiaojun Song
Ben Wang
Rong Zeng
Liqiang Cui
Yuehong Zheng
Wei Ye

Frontiers in Immunology

doi 10.3389/fimmu.2025.1551308

3,870 views
3 citations

Original Research

Published on 20 May 2025

Single-cell transcriptomics reveals cellular dynamics and chemokine CXCL2-mediated smooth muscle cell proliferation in arterial repair

in Inflammation

Xingxiao Huang
Yan Ping
Qiuli Sun
Mingjun Yu
Chao Yang
Xiao Liu
Long Wang
Jinyu Huang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591557

3,336 views
1 citation

Mini Review

Published on 20 May 2025

AI-driven multi-omics profiling of sepsis immunity in the digestive system

in Inflammation

Yuan Gao
Hong Chen
Ruolan Wu
ZuJun Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590526

6,204 views
8 citations

Original Research

Published on 20 May 2025

Aqueous humor cytokines levels and illuminated microcatheter-assisted circumferential trabeculotomy outcome in open-angle glaucoma patients: a 24-month prospective study

in Inflammation

Tingyi Wu
Qianqian Ji
Yanfeng Liao
Xiaoyu Zhao
Ying Hong

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575909

2,123 views

Review

Published on 20 May 2025

Cross-talk between cardiac lymphatics and immune cells regulates inflammatory response and cardiac recovery after myocardial infarction

in Inflammation

Zhihua Yang
Zeyu Zhang
Shaoling Feng
Xujin Ning
Liuli Guo
Yijia Du
Shuai Wang
Xianliang Wang
Jingyuan Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557250

3,975 views
2 citations

Original Research

Published on 19 May 2025

Human Fcγ-receptors selectively respond to C-reactive protein isoforms

in Inflammation

Anna Henning
Johanna Seer
Johannes Zeller
Karlheinz Peter
Haizhang Chen
Julia Thomé
Philipp Kolb
Steffen U. Eisenhardt
Katja Hoffmann
Hartmut Hengel

Frontiers in Immunology

doi 10.3389/fimmu.2025.1598605

4,176 views
2 citations

Original Research

Published on 19 May 2025

Multi-omics analyses construct an inflammatory response based prognostic gene signature for cervical cancer and suggest tumor infiltrating monocytes subgroups as key players

in Inflammation

Yidong Zhang
Jiawei Zhu
Ke Hu
Jie Qiu
Fuquan Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1563593

4,071 views
1 citation

Clinical Trial

Published on 19 May 2025

A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibitor, in patients with mild to moderate atopic dermatitis: a proof-of-concept study with Post-hoc biomarker analysis

in Inflammation

Gyeong Ho Baek
Bo Ri Kim
Jung-Won Shin
Chang Hun Huh
Jungjoong Hwang
Sungmin Ko
Siwon Kim
Pil-Su Ho
Kyu-Han Kim
Chun Wook Park

Frontiers in Immunology

doi 10.3389/fimmu.2025.1560447

5,246 views

Review

Published on 19 May 2025

The impact of innate immunity and epigenetics in the pathogenesis of hidradenitis suppurativa

in Inflammation

Olivia M. Burke
Victoria R. Frerichs
Dario F. Garcia
Rivka C. Stone
Hadar Lev-Tov
Tali Czarnowicki
Robert W. Keane
Nkemcho Ojeh
Jelena Marjanovic
Irena Pastar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593253

6,989 views
6 citations

Mini Review

Published on 19 May 2025

Bile acid-mediated gut-liver axis crosstalk: the role of nuclear receptor signaling in dynamic regulation of inflammatory networks

in Inflammation

Wenlong Yan
Kun Zhang
Jing Guo
Lingfen Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1595486

7,964 views
18 citations

Editorial

Published on 16 May 2025

Editorial: The role of inflammation and immune control in digestive disease and therapeutic approaches

in Inflammation

Zhaoyang Wang
Shuai Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621130

1,431 views

Review

Published on 16 May 2025

New insights into the role of cellular senescence and rheumatic diseases

in Inflammation

Jianting Wen
Jian Liu
Lei Wan
Fanfan Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557402

5,187 views
1 citation

Case Report

Published on 16 May 2025

First successful treatment of epidermolytic Ichthyosis with Vunakizumab: A Case Report

in Inflammation

Wenjie Cheng
Chaolan Pan
Zhe Sun
Peiyi Sun
Jiawen Li
Zhirong Yao
Xiaoxiao Wang
Jia Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1574255

5,952 views
3 citations

Review

Published on 16 May 2025

Novel insights into the crosstalk between non-coding RNA and apoptosis in rheumatoid arthritis: diagnostic functions and therapeutic applications

in Inflammation

Jianting Wen
Jian Liu
Lei Wan
Fanfan Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550839

2,590 views

Original Research

Published on 16 May 2025

Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in rats

in Inflammation

Xingke Song
Haohan Zhu
Zijie Chen
Yifei Wang
Jinling Zhang
Yu Wang
Peijing Rong
Junying Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536056

6,101 views
12 citations

Review

Published on 15 May 2025

The NLRP3 inflammasome: a therapeutic target of phytochemicals in treating atherosclerosis (a systematic review)

in Inflammation

Yongchao Liu
Qianyi Wu
Jing Shao
Youmin Mei
Jie Zhang
Qiuyun Xu
Liming Mao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568722

4,797 views
2 citations

Review

Published on 15 May 2025

Specialized pro-resolving mediators in neutrophil apoptosis regulation: unlocking novel therapeutic potential in kidney diseases

in Inflammation

Yi Kang
Qian Jin
Mengqi Zhou
Huijuan Zheng
Danwen Li
Xuezhe Wang
Jingwei Zhou
Yaoxian Wang
Jie Lv

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589923

4,012 views
3 citations

Original Research

Published on 15 May 2025

Thymic stromal lymphopoietin-activated basophil promotes lung inflammation in mouse atopic march model

in Inflammation

Xu Li
Zizhuo Li
Mindan Tang
Kaoyuan Zhang
Ting Yang
Weilong Zhong
Bo Yu
Fang Wang
Xia Dou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1573130

5,091 views
2 citations

Original Research

Published on 15 May 2025

Intrauterine infusion of autologous platelet-rich plasma modulates endometrial immune status and improves pregnancy outcomes in patients with persistent chronic endometritis

in Inflammation

Xian Chen
Mingye Chen
Meng Liu
Lingbin Qi
Zhiqiang Liu
Cong Chen
Binfa Liang
Xiaobing Yang
Tao Zhang
Yuye Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1528522

5,197 views
5 citations

Original Research

Published on 15 May 2025

Endothelial HSPA12B regulates myocardial monocyte infiltration and inflammatory activity after myocardial infarction

in Inflammation

Yana Wang
Min Fan
Linjian Chen
Patrick Spencer Gill
Xiaohui Wang
Tuanzhu Ha
David L. Williams
Chuanfu Li
Kun Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587898

4,247 views
1 citation

Original Research

Published on 15 May 2025

Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy

in Inflammation

Yongxin Chen
Jue Zhang
Xincheng Feng
Qinghong Ma
Chao Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1569296

3,539 views

Review

Published on 15 May 2025

Immune characteristics of olfactory ensheathing cells and repair of nerve injury

in Inflammation

Ding-yi Chen
Wen-jun Zhang
Cheng Zuo
Yong-sheng Xu
Liu-xiang Fu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1571573

2,286 views
3 citations

Review

Published on 14 May 2025

Friend or foe: the role of platelets in acute lung injury

in Inflammation

Jichun Yang
Xun Zhou
Xinrui Qiao
Meng Shi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556923

5,550 views
6 citations

Correction

Published on 14 May 2025

Corrigendum: MCT4 inhibition attenuates inflammatory response to Mycobacterium avium paratuberculosis infection and restores intestinal epithelial integrity in vitro

in Inflammation

Ala’ Alhendi
Saleh A. Naser

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613909

1,375 views

5,790 articles

articles

Single-cell RNA sequencing identifies two fibroblast subtypes and a Trem2+ macrophage subtype as the possible specific cellular targets in abdominal aortic aneurysms

Single-cell transcriptomics reveals cellular dynamics and chemokine CXCL2-mediated smooth muscle cell proliferation in arterial repair

AI-driven multi-omics profiling of sepsis immunity in the digestive system

Aqueous humor cytokines levels and illuminated microcatheter-assisted circumferential trabeculotomy outcome in open-angle glaucoma patients: a 24-month prospective study

Cross-talk between cardiac lymphatics and immune cells regulates inflammatory response and cardiac recovery after myocardial infarction

Human Fcγ-receptors selectively respond to C-reactive protein isoforms

Multi-omics analyses construct an inflammatory response based prognostic gene signature for cervical cancer and suggest tumor infiltrating monocytes subgroups as key players

A phase 2a double-blind, placebo-controlled, randomized clinical trial evaluating the efficacy and safety of NuGel, a novel topical GPCR19-mediated inflammasome inhibitor, in patients with mild to moderate atopic dermatitis: a proof-of-concept study with Post-hoc biomarker analysis

The impact of innate immunity and epigenetics in the pathogenesis of hidradenitis suppurativa

Bile acid-mediated gut-liver axis crosstalk: the role of nuclear receptor signaling in dynamic regulation of inflammatory networks

Editorial: The role of inflammation and immune control in digestive disease and therapeutic approaches

New insights into the role of cellular senescence and rheumatic diseases

First successful treatment of epidermolytic Ichthyosis with Vunakizumab: A Case Report

Novel insights into the crosstalk between non-coding RNA and apoptosis in rheumatoid arthritis: diagnostic functions and therapeutic applications

Transcutaneous auricular vagus nerve stimulation alleviates inflammation-induced depression by modulating peripheral-central inflammatory cytokines and the NF-κB pathway in rats

The NLRP3 inflammasome: a therapeutic target of phytochemicals in treating atherosclerosis (a systematic review)

Specialized pro-resolving mediators in neutrophil apoptosis regulation: unlocking novel therapeutic potential in kidney diseases

Thymic stromal lymphopoietin-activated basophil promotes lung inflammation in mouse atopic march model

Intrauterine infusion of autologous platelet-rich plasma modulates endometrial immune status and improves pregnancy outcomes in patients with persistent chronic endometritis

Endothelial HSPA12B regulates myocardial monocyte infiltration and inflammatory activity after myocardial infarction

Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy

Immune characteristics of olfactory ensheathing cells and repair of nerve injury

Friend or foe: the role of platelets in acute lung injury

Corrigendum: MCT4 inhibition attenuates inflammatory response to Mycobacterium avium paratuberculosis infection and restores intestinal epithelial integrity in vitro