Frontiers in Oncology

Original Research

Accepted on 01 Dec 2025

MiR-10a-5p Suppresses Hepatocellular Carcinoma Progression and Microvascular Invasion by Targeting TFR1-STAT3-CD24 Signaling Axis

in Cancer Imaging and Image-directed Interventions

Yupeng Zhang
Di Lai
Ziyi Wang
Xiaoyue Nong
Yingying Chen
Rulin Xu
Tao Bai
Wei Zhang

Frontiers in Oncology

139 views

Case Report

Accepted on 01 Dec 2025

Pulmonary Enteric Adenocarcinoma harboring KRAS/TP53/APC mutations with contralateral lung metastasis: Diagnostic Challenges and Molecular Insights

in Thoracic Oncology

Mengjie Mao
Mengling Hu
Qingxiu Tao
Zhuo Zuo
Bin Liu

Frontiers in Oncology

109 views

Systematic Review

Published on 01 Dec 2025

Artificial intelligence based on ultrasound for initial diagnosis of malignant ovarian cancer: a systematic review and meta-analysis

in Gynecological Oncology

Rong Li
Jiehua Lei
Xiaomei Tang
Shiying Zheng
Jiajia Qu
Yueyue Xu
Hongyu Zheng

Frontiers in Oncology

doi 10.3389/fonc.2025.1626286

857 views

Original Research

Published on 01 Dec 2025

Application of radiomics model based on FDG-PET/CT for the assessment of therapeutic effect in patients with newly-diagnosed multiple myeloma

in Hematologic Malignancies

Fukai Li
Fei Li
Xiaodan Xu
Xiang Wang
Qingyang Yu
Guangwen Duan
Jiayang Yan
Baiyang Jiang
Hongbiao Sun
Shaochun Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1647730

548 views

Case Report

Published on 01 Dec 2025

Case Report: High-volume, aggressive prostate cancer with borderline psa levels diagnosed by PSMA PET/CT–based comprehensive radiographic scheme and cognitive fusion targeted biopsy

in Surgical Oncology

Yiheng Zhou
Renyuan Qiu
Mengmeng Dou
Wenkai Bi
Yong Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1721477

732 views

Case Report

Published on 01 Dec 2025

A rare giant congenital intramural uterine cyst: a case report

in Gynecological Oncology

Ping Su
Ben Wang
Su-wei Liu
Yi-ping Yuan
Jian Han

Frontiers in Oncology

doi 10.3389/fonc.2025.1691066

653 views

Original Research

Published on 01 Dec 2025

Histomorphological development and progression of gastric intramucosal papillary adenocarcinoma—a retrospective study

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Yang-Kun Wang
Xiong-Fei Zou
Wen-Yi Wang
Ying-Ying Li
Yan Zhong
Pei Guo
Tao Wang
Si-Liang Xu
Su-Nan Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1681155

474 views

Original Research

Published on 01 Dec 2025

Comparative prognosis of pediatric lymphoblastic lymphoma: insights from Chinese and international cohorts

in Hematologic Malignancies

Luyao Zhang
Jianwen Zhou
Yongyan He
Tianhui Chen
Wei Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1626143

518 views

Review

Published on 01 Dec 2025

The S100 protein family in bladder cancer: mechanisms, clinical value, and targeted therapeutic prospects

in Cancer Cell Signaling

Lihao Zhang
Gang Yang
Lige Huang
Aijia Deng
Mengxin Ao
Jiabing Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1683039

520 views

Brief Research Report

Published on 01 Dec 2025

TREM-1 inhibitor specificity and timing of treatment initiation can impact its therapeutic efficacy in cancer and inflammatory disease

in Cancer Molecular Targets and Therapeutics

Alexander B. Sigalov

Frontiers in Oncology

doi 10.3389/fonc.2025.1689771

622 views

Review

Published on 01 Dec 2025

Sleepyhead, deadly awakening: the dynamics of metastatic organotropism, tumor dormancy and therapeutic implications

in Cancer Molecular Targets and Therapeutics

Soumyajit Sarkar
Suresh P. K.

Frontiers in Oncology

doi 10.3389/fonc.2025.1701031

796 views

Mini Review

Published on 01 Dec 2025

Layilin: a multifunctional hyaluronan receptor in physiology and pathology

in Cancer Molecular Targets and Therapeutics

Chenchen Jin
Yunfeng Zong

Frontiers in Oncology

doi 10.3389/fonc.2025.1721065

3,526 views

Original Research

Published on 01 Dec 2025

Comprehensive risk profiling and long-term cardiovascular toxicity in HER2-positive breast cancer patients treated with trastuzumab

in Cardio-Oncology

Minjing Xia
Shanshan Ding
Xueli Wang
Changdong Zhang
Song Chen
Ming Sun
Chunlin Wu
Xiong Zhang
Meiying Wang
Jia Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1684289

525 views

Case Report

Published on 01 Dec 2025

Case Report: Sebaceous lymphadenocarcinoma arising in parotid gland: eighth documented case with lymph node metastasis

in Head and Neck Cancer

Lu Ru
Fengxian An
Bo Zou

Frontiers in Oncology

doi 10.3389/fonc.2025.1639617

469 views

Original Research

Published on 01 Dec 2025

Study on the application of modified negative pressure wound therapy with instillation in cervical anastomotic leakage after oesophageal cancer surgery

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Linrong Zhou
Cui Li
Xuehong Guan
Jing Xie
Wanli Lin
Bomeng Wu
Ying Chen
Jiawei Huang
Lanjuan Gong

Frontiers in Oncology

doi 10.3389/fonc.2025.1644593

418 views

Original Research

Published on 01 Dec 2025

Identification of NPM and non-mass breast cancer based on radiological features and radiomics

in Breast Cancer

Zhen Guo
Zhuonan Wang
Xin Lin
Xingyu Chen
Wei Liu
Rui Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1665427

571 views

Original Research

Published on 01 Dec 2025

The value of 18F-FDG PET/CT imaging in predicting the efficacy of PD-1/PD-L1 immune checkpoint inhibitors in advanced non-small cell lung cancer

in Pharmacology of Anti-Cancer Drugs

Huiwen Luo
Linlin Li
Jian Wang
Xuefeng Hou
Xiaofeng Li
Wengui Xu
Wen Zhou
Dong Dai

Frontiers in Oncology

doi 10.3389/fonc.2025.1651843

1,036 views

Original Research

Published on 01 Dec 2025

Antitumor efficacy of 5-aminolevulinic acid (5-ALA)-based radiodynamic therapy under single-dose X-ray irradiation in colon cancer

in Pharmacology of Anti-Cancer Drugs

Junko Takahashi
Shinsuke Nagasawa
Xiupeng Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1722919

643 views

Original Research

Accepted on 30 Nov 2025

Preoperative Inflammation-Based Immune Prognostic Nomogram in Bladder Cancer: A Multicenter Study

in Surgical Oncology

Runlin Feng
Jan Zhang
Yanping Tao
Hou Jian
Tai Wenlin

Frontiers in Oncology

196 views

Case Report

Accepted on 30 Nov 2025

Definitive radiotherapy for adenoid cystic carcinoma of main bronchus: A case report with 10-year follow-up

in Radiation Oncology

Sunghyun Nam
Hyungsoon Kim
Doyoon Kim
Jihoon Maeng
Hyo Sup Shim
Dae Joon Kim
Eun Young Kim
Min Hee Hong
Seo Hee Choi
Jaeho Cho

Frontiers in Oncology

125 views

Systematic Review

Accepted on 30 Nov 2025

Saliva and blood miRNAs as complementary biomarkers for esophageal cancer detection

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Mary Kathryn Maxwell
Taichiro Nonaka

Frontiers in Oncology

347 views

Original Research

Accepted on 29 Nov 2025

Radiotherapy is Associated with Survival in Stage I-II Gastric MALT Lymphoma with Failed or Inadequate Anti-Helicobacter Pylori Treatment: A Single-Center Retrospective Analysis

in Gastrointestinal Cancers: Gastric and Esophageal Cancers

Miao Li
Wenjie Wang
Chi Lu
Yujing Zhang

Frontiers in Oncology

131 views

Original Research

Accepted on 28 Nov 2025

Enhancing Molecular Classifying Accuracy of Pediatric CNS Tumors: A Dual-Classifier Approach Using DNA Methylation Profiling

in Pediatric Oncology

Esra Mosa
Rania Alanany
Shimaa Sherif
Erdener Ozer
Sukoluhle Dube
Aayesha Jabeen
Ian Pople
Davide Bedognetti
Ata Maaz
Ayman Saleh

Frontiers in Oncology

238 views

Original Research

Accepted on 28 Nov 2025

HARM-YOLO: An Enhanced YOLOv10 Framework for High-Sensitivity Lung Nodule Detection in CT Imaging

in Thoracic Oncology

Liqun Li
Jing Guo
Yunfei Li
Chendong Li
Jiao Du

Frontiers in Oncology

157 views

34,173 articles

articles

MiR-10a-5p Suppresses Hepatocellular Carcinoma Progression and Microvascular Invasion by Targeting TFR1-STAT3-CD24 Signaling Axis

Pulmonary Enteric Adenocarcinoma harboring KRAS/TP53/APC mutations with contralateral lung metastasis: Diagnostic Challenges and Molecular Insights

Artificial intelligence based on ultrasound for initial diagnosis of malignant ovarian cancer: a systematic review and meta-analysis

Application of radiomics model based on FDG-PET/CT for the assessment of therapeutic effect in patients with newly-diagnosed multiple myeloma

Case Report: High-volume, aggressive prostate cancer with borderline psa levels diagnosed by PSMA PET/CT–based comprehensive radiographic scheme and cognitive fusion targeted biopsy

A rare giant congenital intramural uterine cyst: a case report

Histomorphological development and progression of gastric intramucosal papillary adenocarcinoma—a retrospective study

Comparative prognosis of pediatric lymphoblastic lymphoma: insights from Chinese and international cohorts

The S100 protein family in bladder cancer: mechanisms, clinical value, and targeted therapeutic prospects

TREM-1 inhibitor specificity and timing of treatment initiation can impact its therapeutic efficacy in cancer and inflammatory disease

Sleepyhead, deadly awakening: the dynamics of metastatic organotropism, tumor dormancy and therapeutic implications

Layilin: a multifunctional hyaluronan receptor in physiology and pathology

Comprehensive risk profiling and long-term cardiovascular toxicity in HER2-positive breast cancer patients treated with trastuzumab

Case Report: Sebaceous lymphadenocarcinoma arising in parotid gland: eighth documented case with lymph node metastasis

Study on the application of modified negative pressure wound therapy with instillation in cervical anastomotic leakage after oesophageal cancer surgery

Identification of NPM and non-mass breast cancer based on radiological features and radiomics

The value of 18F-FDG PET/CT imaging in predicting the efficacy of PD-1/PD-L1 immune checkpoint inhibitors in advanced non-small cell lung cancer

Antitumor efficacy of 5-aminolevulinic acid (5-ALA)-based radiodynamic therapy under single-dose X-ray irradiation in colon cancer

Preoperative Inflammation-Based Immune Prognostic Nomogram in Bladder Cancer: A Multicenter Study

Definitive radiotherapy for adenoid cystic carcinoma of main bronchus: A case report with 10-year follow-up

Saliva and blood miRNAs as complementary biomarkers for esophageal cancer detection

Radiotherapy is Associated with Survival in Stage I-II Gastric MALT Lymphoma with Failed or Inadequate Anti-Helicobacter Pylori Treatment: A Single-Center Retrospective Analysis

Enhancing Molecular Classifying Accuracy of Pediatric CNS Tumors: A Dual-Classifier Approach Using DNA Methylation Profiling

HARM-YOLO: An Enhanced YOLOv10 Framework for High-Sensitivity Lung Nodule Detection in CT Imaging