Frontiers in Oncology | Hematologic Malignancies

Original Research

Accepted on 10 Apr 2026

Temporal Trends, Disparities, and ARIMA Forecasts of Mortality Among U.S. Adults with Coexisting Hematologic Malignancy and Heart Failure, 1999–2023, with Projections to 2033

in Hematologic Malignancies

YUE ZHANG
Ying Tian

Frontiers in Oncology

Case Report

Accepted on 10 Apr 2026

A Case of Non-Secretory Multiple Myeloma Presenting with Eosinophilia: Diagnostic Challenges and a Focused Literature Review

in Hematologic Malignancies

Jirui Zhong
Xikun Liu
Jiduo Liu
Shanshan Xiao
Xuekui Gu
Zenghui Liu

Frontiers in Oncology

Methods

Published on 10 Apr 2026

Clinical implementation of a one-step no-wash flow cytometry method allows for real-time monitoring of patients treated with autologous CAR-T cells

in Hematologic Malignancies

Nassim Salem
Clémence Demerlé
Bechara Mfarrej
Ludovic Blaison
Pierre Lignée
Jérôme Couquiaud
Sarah Ouffai
Carine Malenfant
Thibaut Reichert
Julie Demaret

Frontiers in Oncology

doi 10.3389/fonc.2026.1774431

Original Research

Published on 10 Apr 2026

Development of an interpretable machine learning model to predict complete remission and first adverse event in pediatric acute myeloid leukemia using routine clinical data

in Hematologic Malignancies

Ningshu Huang
Weiwei Wang
Rui Yang
Zhihong Liao
Hui Yang
Xi Chen

Frontiers in Oncology

doi 10.3389/fonc.2026.1739432

Case Report

Published on 10 Apr 2026

Case Report: A diagnostic pitfall of diffuse large B-cell lymphoma with hemophagocytic lymphohistiocytosis and atypical tongue pain: the critical role of PET/CT-guided repeat bone marrow biopsy

in Hematologic Malignancies

Lingpeng Meng
Jiayue Li
Ran Chen
Xinlei Wang
Yantong Zhuge
Qingyin Kong
Qipeng Jin
Yiyi Zhang

Frontiers in Oncology

doi 10.3389/fonc.2026.1804997

Case Report

Published on 10 Apr 2026

Fibrin-associated large B-cell lymphoma arising within a hepatic cystic lesion: a case report

in Hematologic Malignancies

Zujun Qin
Yaqi Shu
Qiqi Zhu
Shunhai Jian

Frontiers in Oncology

doi 10.3389/fonc.2026.1689561

Original Research

Accepted on 09 Apr 2026

ATG16L1 and OPTN as a novel prognostic gene expression signature in acute myeloid leukemia survival

in Hematologic Malignancies

Alexandra Teixeira
Joao Alves
Nuria Estévez-Gómez
Ângela Fernandes
Nuno Cerveira
Susana Bizarro
Manuel R. Teixeira
Manuel Guerreiro
Isabel Castro
Belém Sampaio-Marques

Frontiers in Oncology

Original Research

Accepted on 09 Apr 2026

Plasma expression of long non-coding RNA GAS5 and its prognostic significance in newly diagnosed multiple myeloma

in Hematologic Malignancies

Anica Pravdic Divac
Natasa Tosic
Zorica Cvetkovic
Marko Radulovic
Teodora Karan Djurasevic
Aleksandra Tomic
Irena Marjanovic
Natasa Stanisavljevic
Branka Zukic
Olivera Markovic

Frontiers in Oncology

Case Report

Accepted on 09 Apr 2026

A case of type II cryoglobulinemia secondary to diffuse large B-cell lymphoma

in Hematologic Malignancies

Cuiping Mao
Xiaohe Hao

Frontiers in Oncology

Case Report

Accepted on 09 Apr 2026

Lisaftoclax combined with Ixazomib and Dexamethasone after CAR-T for maintenance therapy in transplant-ineligible relapsed/refractory ultra-high risk multiple myeloma: Two case reports and literature review

in Hematologic Malignancies

Weige Xu
Xue Qiao
Linlin Zhang
Lina Xing
Jingnan Zhang
Xiaonan Guo
Shukai Qiao

Frontiers in Oncology

Case Report

Accepted on 09 Apr 2026

POEMS Syndrome with Multiple Ganglioside/Paraneoplastic Antibodies Misdiagnosed as CIDP: A Case Report

in Hematologic Malignancies

He Jiaxiu
Zhao Zhong

Frontiers in Oncology

Case Report

Accepted on 08 Apr 2026

Case report: Leptomeningeal involvement in chronic lymphocytic leukemia (CLL) patients with central nervous system infection: Extramedullary manifestation or transmigration of leukocytes—how to treat this type of CLL?

in Hematologic Malignancies

Tianjiao Zhang
Annette Schuller
Yi Li
Regina Herbst
Korinna Jöhrens
Nicole Schleicher
Ronny Maurer
Mathias Hänel

Frontiers in Oncology

Opinion

Accepted on 07 Apr 2026

Beyond Dual Targeting: Redefining the Treatment Horizon for True Extramedullary Myeloma? – A Critical Appraisal

in Hematologic Malignancies

Ke Qinghua
Shiqiong Zhou

Frontiers in Oncology

Correction

Accepted on 07 Apr 2026

Correction: A mammalian, glutaminase-free asparaginase enhances venetoclax activity in preclinical AML models with chromosome 7 deletion

in Hematologic Malignancies

Hussein A Abbas
Dhabya Majid
ZHE WANG
Amanda M. Schalk
BIn Yuan
Qi Tatarata
Jessica L. Root
Araceli Isabella Garza
Mhd Yousuf Yassouf
Basant T. Gamal

Frontiers in Oncology

Case Report

Accepted on 07 Apr 2026

VA/VHAG alternating consolidation regimen combined with umbilical cord blood and mesenchymal stem cell infusion for the treatment of high-risk MDS patients who are unfit for transplantation: A case report and literature review

in Hematologic Malignancies

Qixin Sun
Zhenzhen Wen
Yanying Ling
Jiongxiang Kuang
Guiping Chen
Zhigang Zhu
Hong Wang
Kangbao Li

Frontiers in Oncology

Systematic Review

Published on 07 Apr 2026

Risk for second primary malignancies in patients with multiple myeloma: a systematic review and meta-analysis

in Hematologic Malignancies

Yingjie Tian
Liang Su
Yujin Li
Minlan Ye
Yuchu Zhang
Qiwei Li
Yongzheng Jiao
Jie Wu

Frontiers in Oncology

doi 10.3389/fonc.2026.1770120

126 views

Original Research

Accepted on 06 Apr 2026

Hybrid Handcrafted and Deep Feature Fusion for Automated Acute Myeloid Leukemia Classification Using TCMA-Net on a Class-Balanced Dataset

in Hematologic Malignancies

Osama M Alshehri
Zohaib Mushtaq
Muhammad Taha
Maham Ijaz
Muhammad Irfan
Malik A. Altayar
Mohammed M Jalal
Mohammed Abu Alghayth
Humood Al Shmrany
Elhashimi Eltayb Hassan

Frontiers in Oncology

Case Report

Accepted on 06 Apr 2026

Case report: Autologous stem cell transplantation in a patient diagnosed with AL amyloidosis in Kazakhstan

in Hematologic Malignancies

Olga Kolesnikova
Vadim Kemaykin
Zhandos Burkitbayev
Azat Karabekov
Alexandr Kolesnev
Ayagul Ainabay
Vildanova Ruzal
Meiramgul Yusupova
Fariza Shokubaeva
Akbota Tursyn

Frontiers in Oncology

Correction

Published on 06 Apr 2026

Correction: Symptom severity clusters in myeloproliferative neoplasms are unrelated to disease phenotype: results from a multicenter survey of the East German study group for hematology and oncology (OSHO #97)

in Hematologic Malignancies

Sabine Felser
Maximilian Koeppel
Rea Kuehl
Philipp le Coutre
Haifa K. Al-Ali
Susann Schulze
Lars-Olof Muegge
Julia Bormann
Jan Geissler
Armin Dadgar

Frontiers in Oncology

doi 10.3389/fonc.2026.1837022

Case Report

Accepted on 02 Apr 2026

Case Report: An Interesting Case of Vision and Hearing Loss Revealing CNS Recurrence in Philadelphia-Positive Acute Lymphoblastic Leukemia

in Hematologic Malignancies

Ifeoma Ike
Victor Samperio
Henry Tsai

Frontiers in Oncology

Case Report

Accepted on 02 Apr 2026

Concurrent Intracranial Hemorrhage and Spontaneous Tumor Lysis Syndrome as the Initial Presentation of KMT2A::AFF1-Rearranged Adult ALL: A Case Report

in Hematologic Malignancies

Yi Yu Lai
Gang Li Zhao
Min Wei
Guo Rong Wei

Frontiers in Oncology

Case Report

Published on 02 Apr 2026

68Ga-pentixafor PET/CT shows better diagnostic performance than 18F-FDG PET/CT in chronic lymphocytic leukemia/small lymphocytic lymphoma: a case report and review of literature

in Hematologic Malignancies

Detao Wu
Ranliang Hua
Ze Mao
Yujing Hu
Jingjie Zhang
Congna Tian
Lu Zheng
Xinchao Zhang
Yanzhu Bian

Frontiers in Oncology

doi 10.3389/fonc.2026.1699568

136 views

Case Report

Published on 02 Apr 2026

Orelabrutinib and rituximab regimen combined with intravitreal methotrexate for treatment of primary vitreoretinal lymphoma: a case report and literature review

in Hematologic Malignancies

Yuxin Li
Ruiyun Qiao
Xuan Zhang
Yahong Li

Frontiers in Oncology

doi 10.3389/fonc.2026.1800529

Case Report

Accepted on 01 Apr 2026

Multiple pulmonary cavities as the prominent manifestation of diffuse large B-cell lymphoma: a case report

in Hematologic Malignancies

Lili Zuo
Yilan Xia
Ruyi Zhang
Min Liu
Jianhui Fan
Lu Qian
Xiao Liang
An Xiao
Jiawei Geng

Frontiers in Oncology

2,149 articles

articles

Temporal Trends, Disparities, and ARIMA Forecasts of Mortality Among U.S. Adults with Coexisting Hematologic Malignancy and Heart Failure, 1999–2023, with Projections to 2033

A Case of Non-Secretory Multiple Myeloma Presenting with Eosinophilia: Diagnostic Challenges and a Focused Literature Review

Clinical implementation of a one-step no-wash flow cytometry method allows for real-time monitoring of patients treated with autologous CAR-T cells

Development of an interpretable machine learning model to predict complete remission and first adverse event in pediatric acute myeloid leukemia using routine clinical data

Case Report: A diagnostic pitfall of diffuse large B-cell lymphoma with hemophagocytic lymphohistiocytosis and atypical tongue pain: the critical role of PET/CT-guided repeat bone marrow biopsy

Fibrin-associated large B-cell lymphoma arising within a hepatic cystic lesion: a case report

ATG16L1 and OPTN as a novel prognostic gene expression signature in acute myeloid leukemia survival

Plasma expression of long non-coding RNA GAS5 and its prognostic significance in newly diagnosed multiple myeloma

A case of type II cryoglobulinemia secondary to diffuse large B-cell lymphoma

Lisaftoclax combined with Ixazomib and Dexamethasone after CAR-T for maintenance therapy in transplant-ineligible relapsed/refractory ultra-high risk multiple myeloma: Two case reports and literature review

POEMS Syndrome with Multiple Ganglioside/Paraneoplastic Antibodies Misdiagnosed as CIDP: A Case Report

Case report: Leptomeningeal involvement in chronic lymphocytic leukemia (CLL) patients with central nervous system infection: Extramedullary manifestation or transmigration of leukocytes—how to treat this type of CLL?

Beyond Dual Targeting: Redefining the Treatment Horizon for True Extramedullary Myeloma? – A Critical Appraisal

Correction: A mammalian, glutaminase-free asparaginase enhances venetoclax activity in preclinical AML models with chromosome 7 deletion

VA/VHAG alternating consolidation regimen combined with umbilical cord blood and mesenchymal stem cell infusion for the treatment of high-risk MDS patients who are unfit for transplantation: A case report and literature review

Risk for second primary malignancies in patients with multiple myeloma: a systematic review and meta-analysis

Hybrid Handcrafted and Deep Feature Fusion for Automated Acute Myeloid Leukemia Classification Using TCMA-Net on a Class-Balanced Dataset

Case report: Autologous stem cell transplantation in a patient diagnosed with AL amyloidosis in Kazakhstan

Correction: Symptom severity clusters in myeloproliferative neoplasms are unrelated to disease phenotype: results from a multicenter survey of the East German study group for hematology and oncology (OSHO #97)

Case Report: An Interesting Case of Vision and Hearing Loss Revealing CNS Recurrence in Philadelphia-Positive Acute Lymphoblastic Leukemia

Concurrent Intracranial Hemorrhage and Spontaneous Tumor Lysis Syndrome as the Initial Presentation of KMT2A::AFF1-Rearranged Adult ALL: A Case Report

68Ga-pentixafor PET/CT shows better diagnostic performance than 18F-FDG PET/CT in chronic lymphocytic leukemia/small lymphocytic lymphoma: a case report and review of literature

Orelabrutinib and rituximab regimen combined with intravitreal methotrexate for treatment of primary vitreoretinal lymphoma: a case report and literature review

Multiple pulmonary cavities as the prominent manifestation of diffuse large B-cell lymphoma: a case report