Frontiers in Oncology | Pharmacology of Anti-Cancer Drugs

Original Research

Published on 05 Sep 2025

Osthole suppresses prostate cancer progression by modulating PRLR and the JAK2/STAT3 signaling axis

in Pharmacology of Anti-Cancer Drugs

Linjun Yan
Jiaqi Mei
Yuanqiao He
Qi Cui
Xiaohong Wang
Feng Lv
Keyue Cao
Yuanjian Shao

Frontiers in Oncology

doi 10.3389/fonc.2025.1630181

399 views

Original Research

Published on 03 Sep 2025

Oleanolic acid alleviates ovarian cancer by regulating the miR-122/PDK4 axis to induce autophagy and inhibit glycolysis in vivo and in vitro

in Pharmacology of Anti-Cancer Drugs

Zhen Zeng
Qing Lin
Jing Yu
Min Lin
Ningwei Zhao

Frontiers in Oncology

doi 10.3389/fonc.2025.1670758

657 views

Original Research

Published on 01 Sep 2025

Effects of parthenolide on amino acid metabolism and oxidative stress in lung adenocarcinoma based on quantitative proteomic analysis, targeted amino acid metabolomics, network pharmacology, and experimental validation

in Pharmacology of Anti-Cancer Drugs

Jiye Liu
Yu Liu
Jiachun Li
Shuang Shen

Frontiers in Oncology

doi 10.3389/fonc.2025.1642866

545 views

Original Research

Published on 01 Sep 2025

Cost-effectiveness analysis of the combination of low-dose nivolumab with triple metronomic chemotherapy for advanced head and neck squamous cell carcinoma in China

in Pharmacology of Anti-Cancer Drugs

Yingdan Cao
Fenghao Shi
Xiaoxia Wei
Sheng Han
Yu Fang

Frontiers in Oncology

doi 10.3389/fonc.2025.1542792

543 views

Original Research

Published on 29 Aug 2025

Negative outcomes associated with tyrosine kinase inhibitors during management of gastrointestinal stromal tumors: examination of data from the FDA adverse event reporting system

in Pharmacology of Anti-Cancer Drugs

Yuxuan Ma
Ahui Fan
Yuhao Wang
Shenhui Xu
Xin Liu
Jianjun Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1608451

546 views

Original Research

Accepted on 27 Aug 2025

Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle

in Pharmacology of Anti-Cancer Drugs

Shengyou Song
Yalin Song

Frontiers in Oncology

doi 10.3389/fonc.2025.1629962

208 views

Review

Published on 27 Aug 2025

Crucial roles of CircRNA-mediated autophagy in digestive cancer

in Pharmacology of Anti-Cancer Drugs

Shenggan Shi
Ailing Wei
Yong Yang
Juan Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1615306

521 views

Review

Accepted on 26 Aug 2025

Recombinant human adenovirus type 5 administration for the treatment of malignant ascites or pleural effusion in cancer patients: a meta-analysis

in Pharmacology of Anti-Cancer Drugs

Changsong Duan
Xue Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1592995

132 views

Original Research

Accepted on 25 Aug 2025

A network pharmacology approach and experimental validation to investigate the anticancer mechanism of diosgenin against esophageal cancer via PI3K/Akt pathway

in Pharmacology of Anti-Cancer Drugs

Jiajia Bi
Jia Wei
Hui Zhang
Jianhui Kang
Yifan Dong
Yiming Xie
Sujuan Chen
Shuangping Ma
Zihan Zhao
Ruifei Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1648781

209 views

Original Research

Published on 18 Aug 2025

Adverse events of pexidartinib for the treatment of TGCT: a real-world disproportionality analysis using FDA Adverse Event Reporting System database

in Pharmacology of Anti-Cancer Drugs

Yu Lin
Xinlei Zheng
Li Lin
Maohua Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1594585

1,005 views

Review

Published on 11 Aug 2025

Chemotherapeutic nanoparticles for glioblastoma

in Pharmacology of Anti-Cancer Drugs

Samantha Messina
Candida Zuchegna
Mara Bruzzi

Frontiers in Oncology

doi 10.3389/fonc.2025.1641752

943 views

Case Report

Published on 07 Aug 2025

Acute thrombocytopenia and fibrinogen reduction occurring after nintedanib treatment for immune checkpoint inhibitor-related pneumonia: a case report

in Pharmacology of Anti-Cancer Drugs

Jian Zheng
Nan Zhou
Dexiang Pang

Frontiers in Oncology

doi 10.3389/fonc.2025.1561440

1,018 views

Original Research

Published on 04 Aug 2025

Integrating network pharmacology and transcriptomics to identify solasonine’s anti-osteosarcoma targets and experimental validation

in Pharmacology of Anti-Cancer Drugs

Daihao Wei
Minyu Li
Dawei Chu
Jiandang Shi

Frontiers in Oncology

doi 10.3389/fonc.2025.1614058

899 views

Review

Published on 30 Jul 2025

Synergistic strategies in photodynamic combination therapy for cancer: mechanisms, nanotechnology, and clinical translation

in Pharmacology of Anti-Cancer Drugs

Daohong Kan
Rong Ding
Huchuan Yang
Yuming Jia
Kaijian Lei
Zhongming Wang
Wei Zhang
Chaokun Yang
Zongjunlin Liu
Fang Xie

Frontiers in Oncology

doi 10.3389/fonc.2025.1607259

992 views
1 citation

Original Research

Published on 30 Jul 2025

PD-L1 expression in microvascular endothelial cells predicts the efficacy and side effects of anlotinib

in Pharmacology of Anti-Cancer Drugs

Yingfang Feng
Yuan Gao
Shaochuan Liu
Tingting Qin
Yan Zhang
Jing Wang
Kai Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1544278

863 views

Editorial

Published on 17 Jul 2025

Editorial: Safety consideration in the development of anti-tumor monoclonal antibodies during drug development

in Pharmacology of Anti-Cancer Drugs

Tao Wang
Shaad Essa Abedin
Jan Willem van der Laan

Frontiers in Oncology

doi 10.3389/fonc.2025.1640377

778 views