Frontiers in Oncology | Radiation Oncology

Original Research

Published on 12 Jan 2026

Determining optimal clinical target volume margins based on microscopic tumor extension in patients with non-small-cell lung cancer undergoing chemotherapy or chemotherapy combined with immunotherapy

in Radiation Oncology

Yujiao Zhang
Xiao Song
Jiaran Li
Fen Zhao
Li Li
Ning Liu
Miaoqing Zhao
Shuanghu Yuan

Frontiers in Oncology

doi 10.3389/fonc.2025.1503615

867 views

Brief Research Report

Published on 12 Jan 2026

Post-radiation levator ani atrophy is associated with worse Low Anterior Resection Syndrome score after nonoperative management for locally advanced rectal cancer: a potential MRI biomarker

in Radiation Oncology

Rehema J. Thomas
Shrey Derasari
Sarah M. Palmquist
Nichole Samms
Lauren Andring
Emma B. Holliday

Frontiers in Oncology

doi 10.3389/fonc.2025.1656898

771 views

Original Research

Published on 12 Jan 2026

Comparison of positioning errors and PTV expansion between the iSCOUT image-guidance system and onboard EPID in rectal cancer radiotherapy: a real-world study

in Radiation Oncology

Bao Wan
Lu Hou
Jiangtao Han
Yongtai Zheng
Chao Liu
Shuo Sun
Yu Zhao
Fukui Huan
Hongkai Wang
Tantan Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1671586

636 views

Original Research

Published on 12 Jan 2026

Assessment of optic disc parameter changes in head and neck cancer patients undergoing radiotherapy based on OCT

in Radiation Oncology

Rui Liu
Pengfei Chen
Keren Zhao
Han Wang
Ping Zhao
Yudan Su

Frontiers in Oncology

doi 10.3389/fonc.2025.1674684

509 views

Methods

Published on 09 Jan 2026

Influencing factors of lymphopenia after conventional fractionated whole-breast radiotherapy following breast-conserving surgery for early breast cancer: a retrospective study

in Radiation Oncology

Yang Sun
Yanan Chen
Ting Liu
Pan Pan
Yongjuan Gu
Xuexue Liang
Dong Shen
Lixian Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1669347

596 views

Editorial

Accepted on 08 Jan 2026

Editorial: Use of Radiation Therapy for Hematological Malignancies

in Radiation Oncology

Carla Hajj
Brandon Imber

Frontiers in Oncology

260 views

Original Research

Published on 08 Jan 2026

Validation of SRS MapCHECK for CyberKnife patient-specific quality assurance: challenges with small cone sizes

in Radiation Oncology

Dohyeon Yoo
Taeho Kim
Hojae Kim
Sangmin Lee
Dong Wook Kim
Jin Sung Kim
Ho Lee
Hojin Kim

Frontiers in Oncology

doi 10.3389/fonc.2025.1667108

741 views

Original Research

Published on 06 Jan 2026

Survival in stage IV non-small cell lung cancer patients based on radiation dose to immune cells: a retrospective analysis

in Radiation Oncology

Changxing Feng
Kang Wang
Tao Hu
Fuhao Xu
Li Li
Shuanghu Yuan

Frontiers in Oncology

doi 10.3389/fonc.2025.1715751

859 views

Correction

Published on 06 Jan 2026

Correction: Benchmarking GPT-5 in radiation oncology: measurable gains, but persistent need for expert oversight

in Radiation Oncology

Ugur Dinç
Jibak Sarkar
Philipp Schubert
Sabine Semrau
Thomas Weissmann
Andre Karius
Johann Brand
Bernd-Niklas Axer
Ahmed Gomaa
Pluvio Stephan

Frontiers in Oncology

doi 10.3389/fonc.2025.1766619

631 views

Original Research

Published on 05 Jan 2026

Spatially fractionated radiation therapy for treating recurrent glioblastoma: a dosimetric feasibility study

in Radiation Oncology

Yuwei Zhou
Sean Tanny
Michael T. Milano
Brian Marples
Fiona Li
Hyunuk Jung
Matthew Webster
Alexander R. Podgorsak
Jihyung Yoon
Wesley Rivais

Frontiers in Oncology

doi 10.3389/fonc.2025.1691132

919 views

Case Report

Published on 05 Jan 2026

Comprehensive management of chest wall recurrent HER2-positive breast cancer with Anlotinib and hypofractionated radiotherapy: a case report

in Radiation Oncology

Jing Xu
Qing Liu
Yue Yin
Guanglu Dong

Frontiers in Oncology

doi 10.3389/fonc.2025.1708884

819 views

Case Report

Published on 19 Dec 2025

Case Report: Navigating novel therapies and systemic barriers in ovarian clear cell carcinoma through a complete response to lenvatinib, pembrolizumab, and SFRT

in Radiation Oncology

Jared Hobson
Allison E. Garda
Jonathan Ticku
Abigail Stockham

Frontiers in Oncology

doi 10.3389/fonc.2025.1679554

1,425 views

Original Research

Published on 19 Dec 2025

The impact of dose rate optimisation and robust optimisation on FLASH proton therapy treatment plan quality and dose rates

in Radiation Oncology

Nathalie Lövgren
Rasmus Nilsson
Erik Traneus
Kristoffer Petersson

Frontiers in Oncology

doi 10.3389/fonc.2025.1638319

1,143 views

Original Research

Published on 17 Dec 2025

Deep learning-based dose prediction for prostate cancer with empty bladder protocol: a framework for efficient and personalized radiotherapy planning

in Radiation Oncology

Byongsu Choi
Deepak K. Shrestha
Albert Attia
Brad J. Stish
James Leenstra
Jean Claude Rwigema
Jiansen Ma
Sung Uk Lee
Jong Hwi Jeong
Jongeun Kim

Frontiers in Oncology

doi 10.3389/fonc.2025.1690416

1,483 views

Case Report

Published on 17 Dec 2025

Case Report: Radiotherapy combined with DEB-TACE for hemorrhagic locally advanced solid tumors: a report of 3 cases

in Radiation Oncology

Yunfeng Guan
Bin Shen

Frontiers in Oncology

doi 10.3389/fonc.2025.1647251

1,305 views

Review

Published on 17 Dec 2025

Current status and upcoming developments for online adaptive proton therapy enabling a closed feedback loop for near real-time adaptation

in Radiation Oncology

Virginia Gambetta
Kristin Stützer
Christian Richter

Frontiers in Oncology

doi 10.3389/fonc.2025.1660605

2,227 views

Mini Review

Published on 16 Dec 2025

Addressing the cancer burden in LMICs: the potential of modulated electro-hyperthermia

in Radiation Oncology

Carrie Anne Minnaar
Mia Hugo
Prinitha Pillay
Thanushree Naidoo
Jeffrey Allen Kotzen
Duvern Ramiah

Frontiers in Oncology

doi 10.3389/fonc.2025.1590920

949 views

Systematic Review

Published on 16 Dec 2025

The research perspectives and frontiers on radiotherapy for hepatocellular carcinoma: a bibliometric analysis and systematic review

in Radiation Oncology

Tao He
Hong Xiao
Bin Yi
Chengyan Zhou
Juan Yang
Ke Sun
Jieyu Zou

Frontiers in Oncology

doi 10.3389/fonc.2025.1601207

1,904 views

Original Research

Published on 15 Dec 2025

Comparative evaluation of symmetry, dosimetry, and toxicity in prostate cancer EBRT with spacing techniques

in Radiation Oncology

Yossi Ben-Dor
Aaron Shachar
Eleonora Kuptzov
Salem Billan
Tomer Charas

Frontiers in Oncology

doi 10.3389/fonc.2025.1668726

1,118 views

Correction

Published on 15 Dec 2025

Correction: Influence factor and mechanism of FLASH effect

in Radiation Oncology

Tingyu Feng
Tianyang He
Wentao Ye
Lisha Xiang

Frontiers in Oncology

doi 10.3389/fonc.2025.1761396

499 views

Original Research

Published on 11 Dec 2025

Proton-boron capture interaction enhances killing of radiation resistant cancer cells

in Radiation Oncology

Dalong Pang
Mira Jung
Alfredo Velena
William Parke
Anatoly Dritschilo

Frontiers in Oncology

doi 10.3389/fonc.2025.1720143

670 views

Original Research

Published on 11 Dec 2025

Are we overestimating proton minibeam therapy effectiveness through physical dose metrics?

in Radiation Oncology

Kaan Dere
Ahmet Cemal Usta
Reyhan Serra Kurnaz
Liyong Lin
Yong Yang
Murat Surucu
Serdar Charyyev

Frontiers in Oncology

doi 10.3389/fonc.2025.1682511

1,360 views

Original Research

Published on 11 Dec 2025

Benchmarking GPT-5 in radiation oncology: measurable gains, but persistent need for expert oversight

in Radiation Oncology

Ugur Dinç
Jibak Sarkar
Philipp Schubert
Sabine Semrau
Thomas Weissmann
Andre Karius
Johann Brand
Bernd-Niklas Axer
Ahmed Gomaa
Pluvio Stephan

Frontiers in Oncology

doi 10.3389/fonc.2025.1695468

1,301 views
1 citation

Original Research

Published on 10 Dec 2025

Upright radiotherapy for breast cancer: a pre-clinical study considering photon and proton beam access, plus arm positioning

in Radiation Oncology

Gordon Sands
Chung Tin Lo
Jemma Nunn
Mark Ramtohul
Simon Ingram
David Cobben
Elizabeth Chabner
Tracy Underwood

Frontiers in Oncology

doi 10.3389/fonc.2025.1668109

1,499 views

2,377 articles

articles

Determining optimal clinical target volume margins based on microscopic tumor extension in patients with non-small-cell lung cancer undergoing chemotherapy or chemotherapy combined with immunotherapy

Post-radiation levator ani atrophy is associated with worse Low Anterior Resection Syndrome score after nonoperative management for locally advanced rectal cancer: a potential MRI biomarker

Comparison of positioning errors and PTV expansion between the iSCOUT image-guidance system and onboard EPID in rectal cancer radiotherapy: a real-world study

Assessment of optic disc parameter changes in head and neck cancer patients undergoing radiotherapy based on OCT

Influencing factors of lymphopenia after conventional fractionated whole-breast radiotherapy following breast-conserving surgery for early breast cancer: a retrospective study

Editorial: Use of Radiation Therapy for Hematological Malignancies

Validation of SRS MapCHECK for CyberKnife patient-specific quality assurance: challenges with small cone sizes

Survival in stage IV non-small cell lung cancer patients based on radiation dose to immune cells: a retrospective analysis

Correction: Benchmarking GPT-5 in radiation oncology: measurable gains, but persistent need for expert oversight

Spatially fractionated radiation therapy for treating recurrent glioblastoma: a dosimetric feasibility study

Comprehensive management of chest wall recurrent HER2-positive breast cancer with Anlotinib and hypofractionated radiotherapy: a case report

Case Report: Navigating novel therapies and systemic barriers in ovarian clear cell carcinoma through a complete response to lenvatinib, pembrolizumab, and SFRT

The impact of dose rate optimisation and robust optimisation on FLASH proton therapy treatment plan quality and dose rates

Deep learning-based dose prediction for prostate cancer with empty bladder protocol: a framework for efficient and personalized radiotherapy planning

Case Report: Radiotherapy combined with DEB-TACE for hemorrhagic locally advanced solid tumors: a report of 3 cases

Current status and upcoming developments for online adaptive proton therapy enabling a closed feedback loop for near real-time adaptation

Addressing the cancer burden in LMICs: the potential of modulated electro-hyperthermia

The research perspectives and frontiers on radiotherapy for hepatocellular carcinoma: a bibliometric analysis and systematic review

Comparative evaluation of symmetry, dosimetry, and toxicity in prostate cancer EBRT with spacing techniques

Correction: Influence factor and mechanism of FLASH effect

Proton-boron capture interaction enhances killing of radiation resistant cancer cells

Are we overestimating proton minibeam therapy effectiveness through physical dose metrics?

Benchmarking GPT-5 in radiation oncology: measurable gains, but persistent need for expert oversight

Upright radiotherapy for breast cancer: a pre-clinical study considering photon and proton beam access, plus arm positioning