Frontiers in Pharmacology | Respiratory Pharmacology

Original Research

Published on 05 Sep 2025

Nasal cells as a bronchial cell surrogate for pre-clinical assessment of drug response in cystic fibrosis

in Respiratory Pharmacology

Malina Barillaro
Julie Avolio
Sharaniyaa Balachandran
Claire Bartlett
Wan Ip
Hong Ouyang
Wenming Duan
Joseph Zabner
Shaf Keshavjee
Christine Bear

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1651122

190 views

Original Research

Accepted on 04 Sep 2025

Lauric acid modulates the cyclooxygenases and nitric oxide pathways and reduces oxidative stress in preventing tracheal hyperresponsiveness in asthmatic Wistar rats

in Respiratory Pharmacology

Indyra Alencar Duarte Figueiredo
Alissa Maria De Oliveira Martins
Alexya Mikelle Teixeira Cavalcanti
Jayne Muniz Fernandes
Ludmila Emilly da Silva Gomes
Gabriel Nunes Machado de Oliveira
Lucas Nóbrega de Oliveira
Isabela Motta Felício
Adriana Maria Fernandes de Oliveira Golzio
Luiz Henrique César Vasconcelos

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1657799

Original Research

Published on 02 Sep 2025

Association between acetaminophen use and 30-day mortality in critically ill patients with pulmonary embolism: a retrospective cohort study using the MIMIC-IV database

in Respiratory Pharmacology

Xincai Wang
Xiankun Lin
Liman Qiu
Xunwei Tu
Linqian Jiang
Xiuling Shang
Long Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1663773

258 views

Original Research

Accepted on 01 Sep 2025

NHANES-Based Assessment of Neutrophil-Percentage-to-Albumin and Neutrophilto-Lymphocyte Ratios as Moderate Predictors of Mortality in Adults with Chronic Respiratory Diseases

in Respiratory Pharmacology

Feng Xu
Pan Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1582120

157 views

Original Research

Published on 29 Aug 2025

Risk of interstitial lung disease in non-small cell lung cancer treated with EGFR-TKI: a real-world pharmacovigilance study

in Respiratory Pharmacology

Xu Miao
Yuan Liu
Xiaoqin Li
Rong Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1652750

634 views

Original Research

Published on 29 Aug 2025

Impact of long-acting glucocorticoids on ICU mortality in septic patients with acute respiratory failure: a MIMIC-IV based cohort study

in Respiratory Pharmacology

Yanhui Deng
Shaoxiang Wang
Shaohua Zhou
Wan Zhao
Aitian Wang
Jingli Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1663974

1,010 views

Original Research

Published on 26 Aug 2025

Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study

in Respiratory Pharmacology

Yunlin Yang
Jinfeng Liu
Yi Hou
Yuxun Wei
Liang Huang
Wei Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584230

689 views

Review

Published on 22 Aug 2025

Dipeptidyl peptidase 1 inhibitors for inflammatory respiratory diseases: mechanisms, clinical trials, and therapeutic prospects

in Respiratory Pharmacology

Dandan Zhang
Wenwen Zhang
Ping Hu
Wei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656316

1,701 views

Original Research

Published on 20 Aug 2025

Optimization of ivacaftor-loaded solid lipid nanoparticles for solubility enhancement

in Respiratory Pharmacology

Akshay Parihar
Bhupendra G. Prajapati
Himanshu Paliwal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1619481

790 views

Original Research

Published on 14 Aug 2025

Active surveillance of adverse drug events in hospitalized patients with pulmonary arterial hypertension based on the global trigger tool

in Respiratory Pharmacology

Mengdan Xu
Shunyu Xiong
Guanquan Chen
Guozhi Li
Suzhen He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533634

716 views

Review

Published on 13 Aug 2025

Unlocking the secrets of glucose metabolism reprogramming: the role in pulmonary diseases

in Respiratory Pharmacology

Zhen Li
Shuo-Xuan Chen
Shuai Jiang
Yi-Nong Yang
Xi-Chan Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551452

827 views

Original Research

Accepted on 11 Aug 2025

Liver X receptor agonist T0901317 alleviates sepsis-induced acute lung injury by enhancing macrophage autophagy

in Respiratory Pharmacology

Ben Wang
Xueling Wu
Yu Zhong
Chaowang Huang
Zhi Xu
Liang Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552034

141 views

Original Research

Published on 08 Aug 2025

The first step for understanding the molecular mechanism of the antifibrotic effect of inhaling 25(OH)-vitamin D3 and 1,25(OH)2-vitamin D3 in the murine model of hypersensitivity pneumonitis

in Respiratory Pharmacology

Marta Kinga Lemieszek
Michał Chojnacki
Iwona Paśnik
Alicja Wilczyńska
Wiktoria Gawryś
Jakub Anisiewicz
Ilona Leśniowska
Michał Kiełbus

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1610165

711 views

Review

Published on 08 Aug 2025

Efficacy and safety of reduning injection for severe pneumonia: a systematic review and meta-analysis

in Respiratory Pharmacology

Yan Wang
Baichuan Xu
Peng Zhang
Suyun Li
Yang Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1591136

999 views

Correction

Published on 07 Aug 2025

Correction: Novel mitophagy inducer TJ0113 alleviates pulmonary inflammation during acute lung injury

in Respiratory Pharmacology

Zhengyuan Liu
Danruo Fang
Kaijun Chen
Lingling Dong
Huaqiong Huang
Zhihua Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667879

463 views

Case Report

Published on 06 Aug 2025

NTRK1-fusion as an acquired resistance mechanism in EGFRex19 mutated NSCLC: a case report

in Respiratory Pharmacology

Jielin Li
Yunyun Shi
Mengge Zheng
Chenkang Yang
Hong Gao
Xiaoling Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571777

1,119 views