Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 31 Oct 2025

Net health benefit of mavacamten for the treatment of Chinese patients with obstructive hypertrophic cardiomyopathy: a model-based economic evaluation

in Translational Pharmacology

Han Bao
Yu Jia
Xingzhi Wang
Michael Hurst
Zoe Cheah
Melissa Ho
Jianwei Xuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1636732

251 views

Original Research

Accepted on 30 Oct 2025

DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

in Translational Pharmacology

Zhijjun Yu
Aihua Jiang
Kai Yang
Lin Zhan
Zifei Xiang
Li Chen
Zheng Kuai
Qiong Yuan

Frontiers in Pharmacology

Original Research

Accepted on 30 Oct 2025

Real-World Patient Outcomes with Blinatumomab and Inotuzumab in Adult Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia: A Retrospective Analysis from Two Romanian Oncology Centers

in Translational Pharmacology

Ion Antohe
Amalia Titieanu
Vlad Andrei Cianga
Cosmin Minciună
Cătălin Dănăilă
Alina Daniela Tanase
Iuliu Ivanov
Loredana Dragoș
Mihaela Zlei
Mihaela Mentel

Frontiers in Pharmacology

Original Research

Accepted on 30 Oct 2025

Metabolomic changes associated with treatment response of neoadjuvant chemotherapy with TEC regimen in HER2-negative breast cancer

in Translational Pharmacology

Kun Fang
Cuiping Wang
Zhenfeng Li
Li Wang
Xintong Wang
Zhenwei Jiang
Mengyuan Wu
Shuo Diao
Mingming Yu
Yang Hai

Frontiers in Pharmacology

Original Research

Accepted on 29 Oct 2025

Galunisertib Attenuates Pulmonary Fibrosis with Silicosis in Mouse via TGF-β/TRAF6/Beclin1 Signaling Pathway

in Translational Pharmacology

Rou Li
Huimin Kang
Aoxiang Hu
Guo Chen
Tinghua Yan
Ting Liu
Zhou Cai
Shi Chen

Frontiers in Pharmacology

145 views

Original Research

Accepted on 24 Oct 2025

Preclinical Evaluation of uPAR-ICG-FVIOs for Dual-Mode Imaging and Magnetic Hyperthermia Therapy in Pancreatic Cancer

in Translational Pharmacology

Fen Jiang
Tao Luo
Kelan Zhang
Chong Wu
Xiaolong Wu
Haojie Yang
Zhigang Chen

Frontiers in Pharmacology

461 views

Review

Accepted on 24 Oct 2025

An Overview of the Mechanistic Approaches of Antifungal Nanomaterials

in Translational Pharmacology

Sarmistha Saha
Nadezhda Sachivkina
Regina Gurina
Ekaterina Neborak
Natallia Zhabo
Marina Avdonina
Maria Molchanova

Frontiers in Pharmacology

339 views

Original Research

Accepted on 24 Oct 2025

In-depth analysis for TKI-driven real-world management of 201 CML patients using TFR

in Translational Pharmacology

Mihnea-Lucian Micu
Cira Simion Florin
Mihnea Zdrenghea
Anca Bojan
Andrada Parvu
Tunde Torok-Vistai
Anca Vasilache
Laura Urian
Bancos Anamaria
Laura Ioana Jimbu

Frontiers in Pharmacology

408 views

Review

Accepted on 24 Oct 2025

Mitochondrial Involvement in PC: Improving Therapeutic Strategies

in Translational Pharmacology

Jiaxin Zhang
Chang Lou

Frontiers in Pharmacology

424 views

Original Research

Published on 24 Oct 2025

Cholestane-3β,5α,6β-triol induces cancer cell death by activating GSDME-mediated pyroptosis

in Translational Pharmacology

Jiaxi Chen
Yuan He
Min Zhao
Zihan Liu
Zixin Su
Chuanzhou Li
Chen Yang
Jieping Zhang
Shuichun Mao
Hua Han

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667156

626 views

Original Research

Published on 23 Oct 2025

Enhanced pharmacokinetic and therapeutic of GSH-responsive mPEG-b-P(HPMA)-SGI1776 conjugate for osteosarcoma

in Translational Pharmacology

Xingchen Shi
Rourou Wang
Zhenghua Zhang
Zixuan Wang
Weibing Xu
Xinhe Shi
Zhe Geng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1676770

624 views

Opinion

Accepted on 22 Oct 2025

Bridging Bench to Bedside: A Dual Use Framework for Chromene Based Anti Obesity and Antiviral Therapeutics

in Translational Pharmacology

Sigrit Karla Chávez-Jiménez
Carlos Josué Solórzano Mata
Avila Curiel Beatriz Xochitl
Efrén Emmanuel Jarquín González
Edgar Zenteno
Hector A. Cabrera-Fuentes

Frontiers in Pharmacology

453 views

Original Research

Published on 21 Oct 2025

Effectiveness and safety of esketamine in laparoscopic surgery patients: a systematic review and meta-analysis of randomized controlled trials

in Translational Pharmacology

Shuhui Wang
Wei Hao
Hao Fan
Jiasheng Wu
Lifang Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1663348

471 views

Review

Accepted on 20 Oct 2025

Morusin as a Drug Candidate: Opportunities, Limitations, and the Path Toward Clinical Translation

in Translational Pharmacology

Hany N Azzam
Ahmed Eldessouki
Kareem A Attallah
Mohamed A. Sadek
Yara M Aboulmagd
Menna Mahmoud
Mohamed I. Fahmy
Riham El-Shiekh
Rania M. Kamal
Hazim O. Khalifa

Frontiers in Pharmacology

118 views

Original Research

Accepted on 20 Oct 2025

Effect of Recombinant Human Erythropoietin on Postoperative Anemia in Children and Adolescents Undergoing Osteosarcoma and Potential Influencing Factors: A Single-center Retrospective Study

in Translational Pharmacology

Lulu Liu
Meili Lin
Yang Wenjun
Difei Yao
Huan Luo
Lingyan Yu
Haibin Dai

Frontiers in Pharmacology

Correction

Published on 20 Oct 2025

Correction: Drug interactions between cephalosporins and 5-FU-based chemotherapy in the treatment of patients with gastrointestinal cancer - an exploratory cohort analysis

in Translational Pharmacology

Robert Siegel
Sophie Schlosser-Hupf
Martina Müller-Schilling
Samer A. Kharroubi
André Gessner
Nahed El-Najjar

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721652

393 views