Frontiers in Pharmacology | Translational Pharmacology

Review

Published on 12 Dec 2025

Relevant pharmacokinetics, bioavailability, and bioequivalence studies on Chlorpheniramine maleate (various species): a review

in Translational Pharmacology

César Alas-Pineda
Dennis J. Pavón-Varela
Kristhel Gaitán-Zambrano
Gustavo Ferrer

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1737690

2,267 views

Correction

Published on 11 Dec 2025

Correction: Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis

in Translational Pharmacology

Juan Duan
Xuantao Hu
Tao Li
Gen Wu
Pengcheng Dou
Zhengxiao Ouyang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1678203

559 views

Original Research

Published on 10 Dec 2025

Real-world patient outcomes with Blinatumomab and Inotuzumab in adult relapsed/refractory B-cell acute lymphoblastic leukemia: a retrospective analysis from two Romanian oncology centers

in Translational Pharmacology

Ion Antohe
Amalia Titieanu
Vlad Andrei Cianga
Cosmin Minciună
Cătălin Dănăilă
Alina Daniela Tănase
Iuliu Ivanov
Loredana Dragoş
Mihaela Zlei
Mihaela Mențel

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684382

1,342 views

Original Research

Published on 10 Dec 2025

Real-world data analysis of the risk of Fournier’s gangrene in patients using sodium-glucose cotransporter 2 inhibitors (SGLT2i)

in Translational Pharmacology

Moritz Hertel
Hanno Jaoulak
Max Heiland
Susanne Nahles
Robert Preissner
Saskia Preissner

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1643866

1,034 views

Review

Published on 09 Dec 2025

Pharmacological effects and application prospects of mussel adhesive proteins

in Translational Pharmacology

Junsha An
Zengmiao Hou
Jiaqi Li
Qian Bi
Shile Huang
Cheng Peng
Fu Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704475

1,887 views
1 citation

Correction

Published on 08 Dec 2025

Correction: DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

in Translational Pharmacology

Zhijun Yu
Aihua Jiang
Kai Yang
Lin Zhan
Zifei Xiang
Li Chen
Zheng Kuai
Qiong Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1756716

1,069 views

Original Research

Published on 08 Dec 2025

Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality

in Translational Pharmacology

Xinyu Zhou
Ning Wang
Jihua Wei
Guizhi Li
Zhengwei Lue
Chang Liu
Qi Bao
Zhe Feng
Minjie Zhang
Hu Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1732154

2,099 views

Original Research

Published on 03 Dec 2025

Essential amino acids preserve intestinal barrier integrity via mitochondrial protection in obesity and gut inflammation

in Translational Pharmacology

Letizia Spataro
Maurizio Ragni
Agnese Segala
Alice Vetturi
Giulia Sofia Marcotto
Luca Canciani
Michele O. Carruba
Roberto Aquilani
Ginetta Collo
Alessandra Valerio

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1694723

2,359 views

Original Research

Published on 03 Dec 2025

Dendrobine promotes bone formation via the canonical Wnt/β-catenin signaling pathway and prevents postmenopausal osteoporosis

in Translational Pharmacology

Shengfa Li
Peili Liang
Jian Chen
Youming Zhang
Haixiong Miao
Ting Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1616070

1,192 views

Original Research

Published on 28 Nov 2025

Preclinical evaluation of uPAR-ICG-FVIOs for dual-mode imaging and magnetic hyperthermia therapy in pancreatic cancer

in Translational Pharmacology

Tao Luo
Kelan Zhang
Chong Wu
Xiaolong Wu
Haojie Yang
Zhigang Chen
Fen Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681718

1,681 views

Review

Published on 28 Nov 2025

Part 1 - imidazolines and the changing face of nasal decongestants

in Translational Pharmacology

Rebecca J. Stinson
Laura R. Sadofsky

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655252

1,961 views

Review

Published on 28 Nov 2025

Part II – imidazolines and rhinitis medicamentosa: how can we tackle the rebound dilemma?

in Translational Pharmacology

Rebecca J. Stinson
Laura R. Sadofsky

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1655254

2,517 views

Original Research

Published on 27 Nov 2025

DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

in Translational Pharmacology

Zhijun Yu
Aihua Jiang
Kai Yang
Lin Zhan
Zifei Xiang
Li Chen
Zheng Kuai
Qiong Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1721188

1,159 views

Case Report

Published on 27 Nov 2025

Case Report: A pharmacist-led precision therapy framework for managing invasive fungal infection in CSF1R-Related leukoencephalopathy post Allo-HSCT

in Translational Pharmacology

Jin Lu
Mengqi Jia
Xinghua Luan
Zhongqiu Zhang
Jingying Wu
Xiaojun Huang
Li Yang
Xincai Zhao
Miaomiao Zhou
Yao Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656503

1,309 views

Original Research

Published on 26 Nov 2025

Intraoperative dexmedetomidine use associated with prolonged postanesthesia care unit recovery time after lung resection: a retrospective cohort study

in Translational Pharmacology

Zhenglian Gao
Yan Jiang
Yixin Liu
Chang Yang
Bangjian Zhang
Ming Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1649139

856 views

Original Research

Published on 25 Nov 2025

Galunisertib attenuates pulmonary fibrosis with silicosis in mouse via TGF-β/TRAF6/Beclin1 signaling pathway

in Translational Pharmacology

Rou Li
Huimin Kang
Aoxiang Hu
Guo Chen
Tinghua Yan
Ting Liu
Shi Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1702511

1,506 views

Clinical Trial

Published on 21 Nov 2025

Clinical trial on the pharmacokinetics, pharmacodynamics and safety of tolvaptan in healthy Chinese males: an open-label, single and multiple dosage, parallel group study

in Translational Pharmacology

Hongzhong Liu
Tao Liu
Ming Liu
Xin Zheng
Wen Zhong
Qian Zhao
Ji Jiang
Pei Hu
Yishi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713702

1,211 views

Original Research

Published on 19 Nov 2025

Metabolomic changes associated with treatment response of neoadjuvant chemotherapy with TEC regimen in HER2-negative breast cancer

in Translational Pharmacology

Kun Fang
Cuiping Wang
Zhenfeng Li
Li Wang
Xintong Wang
Zhenwei Jiang
Mengyuan Wu
Shuo Diao
Mingming Yu
Hai Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1707223

912 views

Mini Review

Published on 19 Nov 2025

Targeting emerging amino acid dependencies and transporters in cancer therapy

in Translational Pharmacology

Alfred Akinlalu
Emmanuel Ogberefor
Tommy Gao
Dali Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1717414

2,178 views

Perspective

Published on 18 Nov 2025

Radioprotection redefined: drug discovery at the intersection of tardigrade biology and translational pharmacology

in Translational Pharmacology

Zhitao Cui
Cong Lin
Huiying Zhao
Xiaohui Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1713914

1,938 views

Review

Published on 17 Nov 2025

An overview of the mechanistic approaches of antifungal nanomaterials

in Translational Pharmacology

Sarmistha Saha
Nadezhda Sachivkina
Regina Gurina
Ekaterina Neborak
Natallia Zhabo
Marina Avdonina
Maria Molchanova

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701446

2,136 views

Review

Published on 14 Nov 2025

Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation

in Translational Pharmacology

Hany N. Azzam
Ahmed M. El-Dessouki
Kareem A. Attallah
Mohamed A. Sadek
Yara M. Aboulmagd
Mennat-Allah M. Hassan
Mohamed I. Fahmy
Riham A. El-Shiekh
Rania M. Kamal
Hazim O. Khalifa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1704535

1,621 views
1 citation

Opinion

Published on 13 Nov 2025

Bridging bench to bedside: a dual-use framework for chromene-based anti-obesity and antiviral therapeutics

in Translational Pharmacology

Sigrit Karla Chávez-Jiménez
Carlos Josué Solórzano-Mata
Beatriz Xóchitl Ávila-Curiel
Efrén Emmanuel Jarquín González
Edgar Zenteno
Hector A. Cabrera-Fuentes

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1666414

1,514 views

Brief Research Report

Published on 10 Nov 2025

Liposomal-synthetic-cannabidiol: preliminary translational evidence of efficacy, tolerability and pharmacokinetics following repeated subcutaneous injections in two goats

in Translational Pharmacology

Yael Shilo-Benjamini
Wiessam Abu Ahmad
Dinorah Barasch
Eran Lavy
Daniel Zilbersheid
Yechezkel Barenholz
Ahuva Cern

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1689226

2,151 views

1,097 articles

articles

Relevant pharmacokinetics, bioavailability, and bioequivalence studies on Chlorpheniramine maleate (various species): a review

Correction: Cimifugin suppresses NF-κB signaling to prevent osteoclastogenesis and periprosthetic osteolysis

Real-world patient outcomes with Blinatumomab and Inotuzumab in adult relapsed/refractory B-cell acute lymphoblastic leukemia: a retrospective analysis from two Romanian oncology centers

Real-world data analysis of the risk of Fournier’s gangrene in patients using sodium-glucose cotransporter 2 inhibitors (SGLT2i)

Pharmacological effects and application prospects of mussel adhesive proteins

Correction: DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality

Essential amino acids preserve intestinal barrier integrity via mitochondrial protection in obesity and gut inflammation

Dendrobine promotes bone formation via the canonical Wnt/β-catenin signaling pathway and prevents postmenopausal osteoporosis

Preclinical evaluation of uPAR-ICG-FVIOs for dual-mode imaging and magnetic hyperthermia therapy in pancreatic cancer

Part 1 - imidazolines and the changing face of nasal decongestants

Part II – imidazolines and rhinitis medicamentosa: how can we tackle the rebound dilemma?

DICAR/DICAR-JP exerts therapeutic effects in brain stroke via the miR-361-5p/PRMT1 pathway

Case Report: A pharmacist-led precision therapy framework for managing invasive fungal infection in CSF1R-Related leukoencephalopathy post Allo-HSCT

Intraoperative dexmedetomidine use associated with prolonged postanesthesia care unit recovery time after lung resection: a retrospective cohort study

Galunisertib attenuates pulmonary fibrosis with silicosis in mouse via TGF-β/TRAF6/Beclin1 signaling pathway

Clinical trial on the pharmacokinetics, pharmacodynamics and safety of tolvaptan in healthy Chinese males: an open-label, single and multiple dosage, parallel group study

Metabolomic changes associated with treatment response of neoadjuvant chemotherapy with TEC regimen in HER2-negative breast cancer

Targeting emerging amino acid dependencies and transporters in cancer therapy

Radioprotection redefined: drug discovery at the intersection of tardigrade biology and translational pharmacology

An overview of the mechanistic approaches of antifungal nanomaterials

Morusin as a drug candidate: opportunities, limitations, and the path toward clinical translation

Bridging bench to bedside: a dual-use framework for chromene-based anti-obesity and antiviral therapeutics

Liposomal-synthetic-cannabidiol: preliminary translational evidence of efficacy, tolerability and pharmacokinetics following repeated subcutaneous injections in two goats