Frontiers in Pharmacology | Translational Pharmacology

Brief Research Report

Accepted on 04 Sep 2025

Buprenorphine and Cannabidiol Co-Administration Reduces Survival in a Mouse Model of Orthopedic Trauma

in Translational Pharmacology

Caroline Bouchard
Genevieve Fregeau
Ian Massé
Louis De Beaumont

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1683842

290 views

Original Research

Published on 03 Sep 2025

Differential carbon source utilization drives metabolic state and resuscitation in antibiotic-tolerant persister cells

in Translational Pharmacology

Yufei Sun
Sweta Roy
Qingbo Yang
Yinjie J. Tang
Dacheng Ren

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1634627

552 views

Original Research

Accepted on 02 Sep 2025

Effect of Structure and Composition of Cationic Liposomes on the Delivery of siRNA In Vitro and In Vivo

in Translational Pharmacology

Daniil Viktorovich Gladkikh
Elena V Shmendel
Darya M Makarova
Mikhail A Maslov
Marina A Zenkova
Elena L. Chernolovskaya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1656671

307 views

Original Research

Published on 02 Sep 2025

Parthanatos drives cognitive decline in repeated brain trauma: MSC-derived exosomes as a novel therapeutic strategy

in Translational Pharmacology

Heba Mohammed Refat M. Selim
Amira A. El-Gazar
Dalaal M. Abdallah
Hagar B. Abo-Zalam
Ghada M. Ragab
Ahmed N. Abdallah
Rabab A. El-Gazar
Sultan Alshehri
Einas M. Yousef
Rayan Ballal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1622018

652 views

Original Research

Accepted on 29 Aug 2025

Breaking the Cancer Code: A Novel DNA Minicircle to Disable STAT3 in Ovarian Cancer Cells SKOV3

in Translational Pharmacology

Adina Gabriela Vasilescu
Andrei Mihai Vasilescu
Livia Elena Sima
Natalia Baran
Stefan Eugen Szedlacsek

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1673427

377 views

Original Research

Published on 29 Aug 2025

c-MYC mRNA destabilization inhibited lethal pancreatic cancer in vivo with significant survival outcomes

in Translational Pharmacology

Jigme P. Dorji
Queenie Chen
Sandali G. Perera
Fizza Aijaz
Petvy Li
Tanjina Sania
Hiroshi Matsui
Chidiebere U. Awah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1630476

940 views

Original Research

Accepted on 28 Aug 2025

A Novel Cytotoxic Anti-B7-H3 Affibody with Therapeutic Potential in Acute Myeloid Leukemia

in Translational Pharmacology

Andrei Mihai Vasilescu
Adina Gabriela Vasilescu
Livia Elena Sima
Cristian V.A. Munteanu
Natalia Baran
Stefan Eugen Szedlacsek

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1684226

406 views

Case Report

Accepted on 28 Aug 2025

Occupational Toxic Encephalopathy Due to 1,2-Dichloroethane Exposure: A Case Series

in Translational Pharmacology

Tongyao Li
Wensi Hu
Xia Rong
Ping Yang
Yu Du
Songbai He
Haibo Tang
Linna Luo
Lin Shi
Junzhao Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542156

271 views

Original Research

Published on 28 Aug 2025

Pharmacokinetics and safety of highly variable nitroglycerin lingual spray (NLS) versus US-licensed nitroglycerin lingual spray reference product (Nitrolingual®): a randomized, four-cycle, four-sequence, partially replicated crossover Phase I bioequivalence clinical trial

in Translational Pharmacology

Yingying Fang
Lu Qi
Yu Wang
Chunyu Han
Qian Zhang
Xiaoyun Liu
Ju Liu
Xiaoqiang Cheng
Yinjuan Li
Yan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1631341

593 views

Editorial

Published on 28 Aug 2025

Editorial: Emerging horizons of metformin: exploring recent advances and addressing challenges in research and clinical utilization

in Translational Pharmacology

Charupong Saengboonmee
Mehrnaz Abbasi
Agnieszka Śliwińska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1674641

744 views

Original Research

Published on 28 Aug 2025

Investigating the feasibility of machine learning to guide personalized red blood cell (RBC) transfusion: analyzing the heterogeneity of RBC transfusion in septic patients with hemoglobin levels of 7–9 g/dL based on the causal forest model

in Translational Pharmacology

Penglei Yang
Jun Yuan
Jie He
Lina Yu
Xue Gu
Xizhen Ding
Qihong Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1615618

537 views

Original Research

Accepted on 25 Aug 2025

Bio-Hybrid Scaffolds Combining Polyvinyl Alcohol and Decellularized Articular Cartilage for the Treatment of Focal Chondral Lesions in Hemophilic Patients

in Translational Pharmacology

Silvia Barbon
Marta Confalonieri
Elena Stocco
Alice D'osualdo
Martina Contran
Pier Paolo Parnigotto
Raffaele De Caro
Silvia Todros
Veronica Macchi
Piero Pavan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1650467

266 views

Review

Published on 25 Aug 2025

Targeted photodynamic therapy: enhancing efficacy through specific organelle engagement

in Translational Pharmacology

Jiawen Tao
Zhifei Yuan
Mengjiao Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667812

695 views

Original Research

Published on 21 Aug 2025

Locked nucleic acid-modified antisense oligonucleotides attenuate scar hyperplasia through targeted inhibition of CTGF

in Translational Pharmacology

Jinhe Li
Xi Wu
Ying Yang
Ruiqi Mao
Zherui Li
Xiujun Zhang
Wenguo Wei
Wendi Wang
Hailong Li
Honggang Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1623640

749 views

Original Research

Published on 21 Aug 2025

Effect of ketamine on cellular immunity and inflammation in patients who undergo laparoscopic colon cancer surgery: a retrospective study

in Translational Pharmacology

Jiajia Ji
Haiping Zhang
Lixia Zhou
Chunlan Fan
Ligen Dai
Shaolei Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1562122

850 views

Original Research

Published on 18 Aug 2025

Published population pharmacokinetic models of mycophenolate sodium: a systematic review and external evaluation in a Chinese sample of renal transplant recipients

in Translational Pharmacology

Tong Gao
Wen Xu
Xiao Li
Qie Guo
Donghua Liu
Xiaolei Zhang
Ping Leng
Jialin Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1632568

604 views