Responsibility and cooperativeness are constrained, not determined

In the last decades, voices from the scientific community have advocated rejection of free will and personal responsibility (e.g., Cashmore, 2010). Interpretations of findings from neuroscience from the last decades have been used to support this deterministic assumption. Recent experiments, for example, have detected brain activity in the prefrontal and parietal cortex up to 10 s before the person is aware of any decision-making process (Soon et al., 2008; see also Libet et al., 1983). This has been interpreted as suggesting that consciousness is a post-hoc phenomenon, caused by unconscious neural activity in the brain. The view of the physical world as determined, and the human brain as the organ that enables the mind, leads to the conclusion that brains and minds are both determined. If free will is an illusion, the ramifications to penal law and personal responsibility need to be reconsidered (Cheema and Virk, 2012). Nevertheless, as humans we have an innate urge to experience a sense of agency or responsibility for our actions (Nichols, 2011). Even when confronted with setbacks, disappointments, and failures, humans maintain a sense of personal responsibility (see Gazzaniga, 2011). Failing to be aware of the self as the cause of one's own actions leads to aggressive and less helpful behavior (Baumeister et al., 2009). This article presents evidence that there is a possibility to develop an adequate sense of responsibility and cooperation in the presence of genetic and environmental adversity.

We used data from a population-based cohort of 15-year old twin pairs, to assess genetic and environmental impact on self-reported Self-directedness and Cooperativeness by classic twin methodology (this data was published in Garcia et al., 2013). Here, however, we also describe the variation of these character traits in monozygotic vs. dizygotic co-twins of individuals with extremely low scores in Self-directedness and Cooperativeness. Self-directedness indicates how responsible, purposeful, reliable and resourceful an individual is in working to achieve her goals and values (i.e., agency), while Cooperativeness indicates how well adapted she is in getting along with others fairly, flexibly and with kindness (i.e., communion). Self-directedness and Cooperativeness are highly predictive of mental health problems across diagnostic categories (Cloninger et al., 1993).

The participants consist of same-sex twins included in the Child and Adolescent Twin Study in Sweden (CATSS), which is a nation-wide, population based, longitudinal twin study of mental health. Currently, the CATSS includes around 20,000 twins, born from 1992 to 2002, and has a response rate of about 80% (Anckarsäter et al., 2011), which makes it the world's largest child- and adolescent psychiatric twin study. At the age of 15 the CATSS-twins of the 1994–1995 birth cohorts completed the short (125 items) or the longer version (238 items) of the Temperament and Character Inventory (TCI; Cloninger et al., 1993). The overall TCI response rate was about 55% and the total number of participants was 2714 (369 of whom completed the longer TCI as part of a clinical study). Zygosity is determined by a validated algorithm with a >95% predictive value compared to DNA-testing (Hannelius et al., 2007). In order to use all TCI responses, we extracted the items from the 238-version that correspond to the 125-version (see Garcia et al., 2013). Mx and SAS (version 9.3) softwares were used to disentangle the genetic and environmental contribution of Self-directedness and Cooperativeness. Intra-class correlations and univariate genetic analyses, by structural equation modeling, were calculated on the continuous scores of each dimension separately. A total of 831 adolescent same-sex twin pairs (423 monozygotic pairs and 408 dizygotic pairs) were used in this specific analysis.

We used the TCI mean and standard deviation scores of the 1994-CATSS cohort (n = 1340) in order to standardize the twins' Self-directedness and Cooperativeness scores to t-scores (IBM SPSS version 19) and identified the probands whose t-scores were ≤2 standard deviations below the general population's mean in each character dimension. If both twins in a pair met this criterion, one of them was randomly identified as proband and the other as co-twin. We found 28 monozygotic-twins and 32 dizygotic-twins who showed extremely low Self-directedness and 25 monozygotic-twins and 22 dizygotic-twins who showed extremely low Cooperativeness. In order to not depend on self-assessments alone, co-twins to probands who also had a parent rated DSM-IV disruptive behavior disorder (i.e., attention-deficit/hyperactivity disorder, oppositional defiant disorder or conduct disorder according to parent interviews by the Autism—Tics, AD/HD and other Comorbidities Inventory; Hansson et al., 2005) were specifically indicated in the plots. Twenty-nine percent of the variance in Self-directedness was attributable to genetic factors, 22% to environmental factors that make the twins reared together similar, and 49% to environmental factors that make the twins dissimilar. Thirty-eight percent of Cooperativeness was attributable to genetic factors, 21% to environmental factors that make twins similar, and 41% to environmental factors that make twins dissimilar (see Garcia et al., 2013).

Both monozygotic and dizygotic co-twins of probands with extremely low Self-directedness and Cooperativeness had an increased probability of reporting low (≤1 standard deviations) or extremely low Self-directedness and Cooperativeness (≤2 standard deviations) as compared to the general population (see Figure 1, population mean = 50, standard deviation = 10), but a considerable number of these individuals had developed character in the average or high range, in spite of having exactly the same, or half the genetic susceptibility of the problem-laden individuals. Co-twins to probands with both self-reported and objectively observed problems did not differ from the overall pattern.

Figure 1

Environmental and genetic adversities thus clearly give unequal opportunities to develop a sense of self-control, cooperation, and responsibility, but with a substantial plasticity. This study shows that it is possible to develop a mature character in spite of a genetic make-up and/or early environment associated with a deficient sense of responsibility and cooperation. A self-reported sense of responsibility and cooperation may not reflect actual freedom of action, but the scales used here were developed to assess the degree to which a person experiences that her behaviors over the life-span actually converge with her intentions, desires and conceptualized goals. The scales have also been shown to measure constructs that are highly relevant for mental health, including pro-social and constructive behavior patterns (Cloninger, 2004).

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