About this Research Topic
Single-entity electrochemistry has attracted increasing attention over the past several decades, motivated by the unique electrochemical properties of a single entity that is masked in ensemble-average measurements. Recently, single-entity electrochemistry has been applied in many areas ranging from electrocatalytic amplification and direct electrochemical reaction of single nanoparticles to single cell and single molecule detection of biologically relevant samples. Considerable experimental and theoretical effort has been devoted to studying the electrochemical properties of these entities, which have significant practical applications in the analysis of size, structure, and catalytic characteristics of individual entities based on high-resolution electrochemical measurements.
Nowadays, it is possible to expand the application of single-entity electrochemistry to a broad range of electrochemical measurements. It will certainly help to achieve improved understanding of the intrinsic properties of individual entities to dynamic electrochemical behaviors at the micro/nano interface. Owing to remarkable sensitivity, we anticipate that single entity electrochemistry is not only a unique tool for understanding fundamental electron transfer kinetics at the micro/nano interface where electrochemical reactions processes take place, but also a diverse and commercially successful tool to be used in practical applications.
Significant advances have been made in high-sensitivity measurement of analytes at scales as small as a single molecule, nanoparticle, cell, and even single tissue. Despite ongoing efforts, the main challenges in single-entity electrochemistry include the transient nature and ultra-low amplitude of electrochemical signals from individual entities, the construction of an appropriate electrode interface, and the identification of well-defined electrochemical signals amid noise.
In this Research Topic, we welcome submissions of Original Research and Review articles on themes including, but not limited to:
• Single entity electrochemistry for the investigation of individual particles
• Novel insights in single molecule electrochemistry
• Highly sensitive electrochemical sensors for measuring single entities
• Advances in nanoelectrochemistry and nanoelectrode development
• Complementary use of Nano SECM/SECCM/SICM techniques
Topic editor Caleb Hill is the co-owner of Wyonics LLC, an R&D company focused on ionic liquid-based technologies. The other Topic Editors declare no competing interests.
Keywords: Single nanoparticle, Single molecule, nanoelectrochemistry, Nanoelectrode
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