ORIGINAL RESEARCH
Accepted on 22 Sep 2025
QSAR-based Physiologically Based Pharmacokinetic (PBPK) Modeling for 34 Fentanyl Analogs: Model Validation, Human Pharmacokinetic Prediction and Abuse Risk Insights
doi 10.3389/fphar.2025.1692293
- 575 views
- Frontiers in Pharmacology
- Drug Metabolism and Transport
- Research Topics
- Integrated PK/PD and Drug Metabolism Approaches in Drug Development and Evaluation
Integrated PK/PD and Drug Metabolism Approaches in Drug Development and Evaluation
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Articles
ORIGINAL RESEARCH
Accepted on 18 Sep 2025
Study on Cerebrospinal Fluid Meropenem, Vancomycin and Tigecycline Monitoring in Patients with Central Nervous System Infection Following Neurosurgery Under Different Drug Regimens
doi 10.3389/fphar.2025.1666168
- 742 views
ORIGINAL RESEARCH
Published on 09 Sep 2025
Synthesis, pharmacokinetic studies, and metabolite analysis of meridianin C in rats using a validated ultra high performance liquid chromatography-tandem mass spectrometry method
doi 10.3389/fphar.2025.1633157
- 609 views
ORIGINAL RESEARCH
Published on 19 Aug 2025
Population pharmacokinetics/pharmacodynamics analysis confirming biosimilarity of SB16 to reference denosumab
doi 10.3389/fphar.2025.1631034
- 935 views
ORIGINAL RESEARCH
Published on 29 Apr 2025
Effect of ABCB1 SNP polymorphisms on the plasma concentrations and clinical outcomes of rivaroxaban in Chinese NVAF patients: a population pharmacokinetic-based study
doi 10.3389/fphar.2025.1574949
- 1,658 views
ORIGINAL RESEARCH
Published on 28 Apr 2025
Prediction of pharmacokinetic/pharmacodynamic properties of aldosterone synthase inhibitors at drug discovery stage using an artificial intelligence-physiologically based pharmacokinetic model
doi 10.3389/fphar.2025.1578117
- 2,617 views
- 2 citations
ORIGINAL RESEARCH
Published on 10 Apr 2025
A mechanistic quantitative systems pharmacology model platform for translational efficacy evaluation and checkpoint combination design of bispecific immuno-modulatory antibodies
doi 10.3389/fphar.2025.1571844
- 1,639 views
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