ZL
zhiwen luo
Fudan University
Shanghai, China
About this Research Topic
This Research Topic is closed for submissions.
Background
Exercise is foundational in augmenting health and combating chronic diseases, including cancer, diabetes, and heart disorders. Engaging regularly increases metabolic rates, decreases inflammation, and enhances immune activity, furnishing numerous therapeutic effects. Omics technologies, such as genomics and proteomics, have greatly advanced our knowledge by elaborating how exercise impacts molecular interactions within cells and influences disease pathways. Despite these technological advancements, conclusive connections between specific mechanisms and therapeutic outcomes in exercise still necessitate deeper investigation.
This Research Topic seeks to elucidate the pathways through which physical activity aids in mitigating chronic illnesses, specifically targeting cancer, diabetes, and metabolic disorders. An emphasis will be placed on identifying critical molecular pathways and biomarkers affected by physical activity, employing omics technologies to dissect the intricate dynamics between exercise and disease biology. The overarching intent is to harness these insights to fabricate exercise-based therapeutic strategies, tailored personal interventions, and innovate in precision medicine.
The scope of this Research Topic is extensive yet focused, examining how exercise influences chronic disease treatments through omics analyses. We aim to elucidate:
o The molecular mechanisms of exercise in managing cancer, diabetes, and metabolic diseases.
o Omics-driven insights into how exercise modifies gene expression, protein synthesis, and metabolic pathways.
o The role of physical activity in immune modulation and as an anti-inflammatory agent.
o The influence of exercise on the tumor microenvironment.
o The development of personalized exercise programs based on omics profiling.
This Research Topic seeks original research, comprehensive review articles, and forward-thinking conceptual papers to deepen our understanding of the role exercise plays in the prevention and treatment of chronic diseases. Contributions should aim to bridge laboratory research and clinical application, thus enhancing the translation of exercise science into practical health solutions for chronic disease management.
Keywords: Exercise, Chronic Diseases, Molecular mechanism, Multi-Omics, Therapeutic Strategies
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
