Frontiers in Bioengineering and Biotechnology | Tissue Engineering and Regenerative Medicine

Original Research

Published on 02 Jan 2026

New applications of sustainable, scalable, standardized, and cost-effective human biomaterials for cell-based assays, tissue engineering, and regenerative medicine

in Tissue Engineering and Regenerative Medicine

Rebekka J. S. Salzmann
Sandra Domazet
Sonia Prado-López
Seyda Kigili
Winfried Neuhaus
Andreas Brachner
Gerda Egger
Lorenzo Moroni
Johannes Hackethal

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1676369

1,263 views

Original Research

Published on 19 Dec 2025

Experimental study on tissue-engineered urethral graft for repairing urethral defects in a rabbit model

in Tissue Engineering and Regenerative Medicine

Aodi Jiang
Yu Tian
Chengyang Sun
Ying Lian
Hongfeng Zhai

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1711552

912 views

Case Report

Published on 18 Dec 2025

Autologous platelet-rich gel for refractory plantar ulcer following ethanol sclerotherapy of peripheral venous malformation: a Case Report

in Tissue Engineering and Regenerative Medicine

Zhenyu Zhao
Shaohui Wu
Xiaoyan He
Yan Zhang
Xuemei Chen
Jie Tang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1700377

838 views

Original Research

Published on 18 Dec 2025

Necrostatin-1 alleviates temporomandibular joint osteoarthritis and inhibits chondrocyte senescence and necroptosis possibly via p53/ MAPK downregulation

in Tissue Engineering and Regenerative Medicine

Ying Zhang
Wenyi Cai
Antong Wu
Rui Li
Xin Li
Kaihan Zheng
Yufu Lin
Qingbin Zhang
Wei Cao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1735484

1,149 views

Case Report

Published on 10 Dec 2025

Innovative reconstruction protocol for complex alveolar ridge defects in posterior mandible: Case Report and technical analysis

in Tissue Engineering and Regenerative Medicine

Jian Feng
Kewen Jia
Siyu Chen
Sicong Ren
Yuzhu Han
Mucong Li
Yidi Zhang
Yanmin Zhou

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1693842

960 views

Original Research

Published on 09 Dec 2025

Combined bone marrow mesenchymal stem cell-derived nanovesicles and low-level laser therapy potentiate proliferation and osteogenesis of bone marrow mesenchymal stem cells

in Tissue Engineering and Regenerative Medicine

Jingwei Zhang
Tonghao Yao
Qi Han
Yongqiang Mo
Dailuo Li
Zhengye Zhang
Lihuang Cui
Zhibin Geng
Weitao He
Jingtao Chen

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1676777

1,389 views

Correction

Published on 05 Dec 2025

Correction: Advances in using biomaterials for repairing thin endometrium

in Tissue Engineering and Regenerative Medicine

Huizhen Li
Feihong Hu
Fuchen Xie
Xuedong Chen
Honglian Wu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1749049

1,101 views

Original Research

Published on 04 Dec 2025

Synoviocyte–chondrocyte triculture model for early-stage PTOA: fibronectin fragment-induced catabolic effects in vitro and in vivo

in Tissue Engineering and Regenerative Medicine

Shahid Khan
Hongsik Cho
Karen A. Hasty
Taylor Brown
Sarayu Bhogoju
Anuradha Subramanian

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1683333

1,426 views

Editorial

Published on 04 Dec 2025

Editorial: Role of induced pluripotent stem cells (iPSCs) in regenerative medicine, disease modeling and drug discovery

in Tissue Engineering and Regenerative Medicine

Kim C. O’Connor
Hayden J. Stanley
Bruce A. Bunnell
Raffaele De Caro

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1734717

1,669 views

Original Research

Published on 03 Dec 2025

Electrospun bioactive polymer biomaterials enriched with collagen and platelet-rich plasma as a platform for in vitro chondrogenic differentiation of human mesenchymal stem cells

in Tissue Engineering and Regenerative Medicine

Paulina Trzaskowska
Ewa Rybak
Kamil Kopeć
Tomasz Ciach
Piotr Wieciński
Wojciech Święszkowski
Ewa Kijeńska-Gawrońska

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1629912

1,367 views

Original Research

Published on 02 Dec 2025

Can titanium miniplates provide superior fixation compared to reconstruction plates in mandibular repair with iliac crest flaps? A retrospective study

in Tissue Engineering and Regenerative Medicine

Wen-qing Lin
Da Liu
Renbin Zhou
Hao Lin
Bang Zeng
Jun Jia
Yifang Zhao
Bing Liu
Tianfu Wu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1688458

1,040 views

Review

Published on 02 Dec 2025

Applications of bone regenerative medicine in the foot and ankle: mechanisms, technologies, and therapeutic advances

in Tissue Engineering and Regenerative Medicine

Lianbo Yang
Yijie Li
Tianqi Wang
Zhuo Zhao
Wang Li
Jinghang Lv
Haoran Chen
Zhaodong Qi
Xinming Wang
Wenchi Bao

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1653964

1,955 views

Original Research

Published on 02 Dec 2025

Allogenic Achilles-tendon–bone grafts enable more complete restoration of the native direct enthesis structure in the repair of chronic massive rotator cuff tears

in Tissue Engineering and Regenerative Medicine

Fengyuan Zhao
Xinrui Fu
Jiahao Zhang
Lin Lin
Yu Mei
Yu Yin
Jianquan Wang
Hui Yan

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1684811

1,493 views

Original Research

Accepted on 28 Nov 2025

EXPERIMENTAL EVALUATION OF THE HEALING POTENTIAL OF SESUVIUM PORTULACASTRUM IN EXCISIONAL WOUNDS IN WISTAR RATS

in Tissue Engineering and Regenerative Medicine

Kelly Kercy Nogueira Da Silva
Gislainy Luciana Gomes Câmara
Salvador Viana Gomes Júnior
Camila Gomes Fernandes De Souza
Kizzy Millenn De Freitas
Amália Cinthia Meneses Do Rego
IRAMI ARAÚJO FILHO
Roque Ribeiro Da Silva Junior
Thales Allyrio Araújo De Medeiros Fernandes
José Rodolfo Lopes De Paiva Cavalcanti

Frontiers in Bioengineering and Biotechnology

354 views

Original Research

Published on 28 Nov 2025

Injection of concentrated growth factors from plasma for treating large chronic lower-extremity ulcers defects

in Tissue Engineering and Regenerative Medicine

Zhiqiang Zhang
Nan Cao
Chaoqi Zuo
Xuan Guo
Yilei Wu
Yongxia Liu
Guoyan Liu
Xueqing Wang
Shengji Zhou
Haixia Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1681705

1,000 views

Review

Published on 28 Nov 2025

Decoding the exosomal secretome: stem cell-elicted microenvironmental reprogramming for anterior cruciate ligament regenerative medicine

in Tissue Engineering and Regenerative Medicine

Junjie Chen
Jiayang He
Dujiang Yang
Yuhan He
Yuhao Wei
Zhiqiang Zhang
Xue Zhou
Ming Cheng

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1691651

1,510 views

Editorial

Published on 27 Nov 2025

Editorial: Advances in biotechnological approaches for reproductive tissue engineering

in Tissue Engineering and Regenerative Medicine

Gustavo Henrique Doná Rodrigues Almeida
Fabiana Fernandes Bressan
Maria Angelica Miglino
Moon Suk Kim
Ana Claudia Oliveira Carreira

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1738886

1,138 views

Original Research

Published on 26 Nov 2025

Low-temperature plasma improves the healing process of Achilles tendinopathy in a rat model

in Tissue Engineering and Regenerative Medicine

Suying Wang
Juan Li
Qingyan Pan
Jiahe Li
Long Zhao
Yuhan Zhou
Gang Wang
Ming Zhou
Yangxiaoxue Liu
Aiguo Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1656449

1,129 views

Original Research

Published on 25 Nov 2025

Resonant acoustic mixing-assisted fabrication and evaluation of FDM-printed PLA/β-TCP scaffolds for bone tissue engineering

in Tissue Engineering and Regenerative Medicine

Yixuan Zhu
Jiangqi Hu
Bin Luo
Xuening Deng
Siyu Xie
Jiuning Huang
Yafei Yuan
Qingsong Jiang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1691481

1,265 views

Review

Published on 25 Nov 2025

Mesenchymal stem cell therapy for pulmonary hypertension: an update

in Tissue Engineering and Regenerative Medicine

Renmei Tian
Shangfu Xu
Chan Liu
Yuying Wang
Yutong Wu
Lisheng Li
Juan Liu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1692396

1,819 views

Methods

Published on 21 Nov 2025

Application of rebound tonometer on skin surface pressure measurement: a pilot proof of concept study

in Tissue Engineering and Regenerative Medicine

Weiwei Bian
Wei Ding
Lan Yang
Ying Wu
Ying Huang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1662361

818 views

Review

Published on 21 Nov 2025

Harnessing strontium in regenerative dentistry: progress and perspectives

in Tissue Engineering and Regenerative Medicine

Wenjing Zhang
Lingfei Wei

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1724610

1,303 views
1 citation

Systematic Review

Published on 20 Nov 2025

Clinical effect of immunomodulatory therapy in periodontitis: a systematic review and meta-analysis

in Tissue Engineering and Regenerative Medicine

Yubing Zhang
Xu Qin
Jiexuan Yang
Hannah M. Rogers
Babak Baban
Siwei Tian

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1693365

1,475 views

Original Research

Published on 19 Nov 2025

A novel olecranon-type tracheotomy and expansion forceps for single-person emergency airway access

in Tissue Engineering and Regenerative Medicine

Liang Zhu
Fanhao Meng
Nenghao Jin
Lejun Xing
Yi Wang
Haizhong Zhang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1712809

820 views

1,189 articles

articles

New applications of sustainable, scalable, standardized, and cost-effective human biomaterials for cell-based assays, tissue engineering, and regenerative medicine

Experimental study on tissue-engineered urethral graft for repairing urethral defects in a rabbit model

Autologous platelet-rich gel for refractory plantar ulcer following ethanol sclerotherapy of peripheral venous malformation: a Case Report

Necrostatin-1 alleviates temporomandibular joint osteoarthritis and inhibits chondrocyte senescence and necroptosis possibly via p53/ MAPK downregulation

Innovative reconstruction protocol for complex alveolar ridge defects in posterior mandible: Case Report and technical analysis

Combined bone marrow mesenchymal stem cell-derived nanovesicles and low-level laser therapy potentiate proliferation and osteogenesis of bone marrow mesenchymal stem cells

Correction: Advances in using biomaterials for repairing thin endometrium

Synoviocyte–chondrocyte triculture model for early-stage PTOA: fibronectin fragment-induced catabolic effects in vitro and in vivo

Editorial: Role of induced pluripotent stem cells (iPSCs) in regenerative medicine, disease modeling and drug discovery

Electrospun bioactive polymer biomaterials enriched with collagen and platelet-rich plasma as a platform for in vitro chondrogenic differentiation of human mesenchymal stem cells

Can titanium miniplates provide superior fixation compared to reconstruction plates in mandibular repair with iliac crest flaps? A retrospective study

Applications of bone regenerative medicine in the foot and ankle: mechanisms, technologies, and therapeutic advances

Allogenic Achilles-tendon–bone grafts enable more complete restoration of the native direct enthesis structure in the repair of chronic massive rotator cuff tears

EXPERIMENTAL EVALUATION OF THE HEALING POTENTIAL OF SESUVIUM PORTULACASTRUM IN EXCISIONAL WOUNDS IN WISTAR RATS

Injection of concentrated growth factors from plasma for treating large chronic lower-extremity ulcers defects

Decoding the exosomal secretome: stem cell-elicted microenvironmental reprogramming for anterior cruciate ligament regenerative medicine

Editorial: Advances in biotechnological approaches for reproductive tissue engineering

Low-temperature plasma improves the healing process of Achilles tendinopathy in a rat model

Resonant acoustic mixing-assisted fabrication and evaluation of FDM-printed PLA/β-TCP scaffolds for bone tissue engineering

Mesenchymal stem cell therapy for pulmonary hypertension: an update

Application of rebound tonometer on skin surface pressure measurement: a pilot proof of concept study

Harnessing strontium in regenerative dentistry: progress and perspectives

Clinical effect of immunomodulatory therapy in periodontitis: a systematic review and meta-analysis

A novel olecranon-type tracheotomy and expansion forceps for single-person emergency airway access