Frontiers in Cell and Developmental Biology

Original Research

Published on 24 Apr 2025

TAL1 overexpression in induced pluripotent stem cells promotes the formation of hematopoietic cell-forming complexes but inhibits enucleation in vitro

in Stem Cell Research

Arim Shin
Sung Ah Park
Ji Yeon Kim
Eun Jung Baek

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1474631

490 views

Original Research

Accepted on 23 Apr 2025

Optimal Sca-1-Based Procedure for Purifying Mouse Adipose-Derived Mesenchymal Stem Cells with Enhanced Proliferative and Differentiation Potential

in Stem Cell Research

Xingyu Tao
Jialian Wang
Yuan Yan
Peifeng Cheng
Bin Liu
Huimin Du
Bailin Niu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1566670

134 views

Original Research

Accepted on 23 Apr 2025

Characterization and Neurogenic Responses of Primary and Immortalized Müller Glia

in Stem Cell Research

Thi-Hang Tran
Donny Lukmanto
Mei Chen
Olaf Strauss
Toshiharu Yamashita
Osamu Ohneda
Shinichi Fukuda

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1513163

Original Research

Published on 23 Apr 2025

Dapagliflozin ameliorates intestinal stem cell aging by regulating the MAPK signaling pathway in Drosophila

in Stem Cell Research

Jinhua Yan
Chenxi Feng
Hanmei Zhang
Ting Luo
Haiyang Chen
Haiou Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1576258

383 views

Original Research

Accepted on 22 Apr 2025

Generation and functional characterization of tuft cells in non-human primate pancreatic ducts through organoid culture systems

in Stem Cell Research

Kosuke Sakaguchi
Chiemi Nakajima Kimura
Akihiko Inaba
Yoshiko Hatano
Hanako Ogawa
Yuichi Koshiishi
Keisuke Tanaka
Tatsuya Kometani
Makoto Ohmoto
Koji Sato

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593226

Review

Published on 22 Apr 2025

The role of endothelial cells in pancreatic islet development, transplantation and culture

in Stem Cell Research

Ajun Geng
Shubo Yuan
Qing Cissy Yu
Yi Arial Zeng

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1558137

531 views

Original Research

Accepted on 14 Apr 2025

Revolutionizing Bone Regeneration and Wound Healing: Mechanical Stromal Vascular Fraction and Hyaluronic Acid in a Mouse Calvaria Defect Model

in Stem Cell Research

Riccardo Ossanna
Lindsey Alejandra Quintero Sierra
Sara Ghazanfar Tehrani
Vivekanand Jha
Chiara Curatola
Alice Busato
Anita Conti
Giamaica Conti
Nicola Zingaretti
Pier Camillo Parodi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1582083

161 views

Review

Accepted on 14 Apr 2025

A comprehensive analysis of induced pluripotent stem cell (iPSC) production and applications

in Stem Cell Research

Margarita Matiukhova
Anastasia Ryapolova
Vladimir Andriianov
Vasiliy Reshetnikov
Sophia Zhuravleva
Roman Ivanov
Karabelsky Alexander
Ekaterina Minskaia

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1593207

Brief Research Report

Accepted on 11 Apr 2025

Using a Brain-like Endothelial Cell Differentiation to Characterize the CS79iBRCA-n2 BRCA1 Mutated Patient Derived Stem Cell Line

in Stem Cell Research

Natalie G Alexander
Kylie A Buchanan
Alexandra E Meyer
Lauren M Mitterway
Caroline O Vanderburgh
Shreyas S. Rao
Brandon J Kim

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1516669

161 views

Review

Accepted on 10 Apr 2025

Challenges of in vitro modelling of liver fibrosis

in Stem Cell Research

Patricia Ros-Tarraga
Estela Villanueva-Badenas
Estela Sanchez-Gonzalez
Gloria Gallego-Ferrer
M. Teresa Donato
Laia Tolosa

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1567916

Original Research

Published on 08 Apr 2025

Engineered mesenchymal stromal cells with interleukin-1beta sticky-trap attenuate osteoarthritis in knee joints

in Stem Cell Research

Christopher Kim
Biao Li
Sayaka Nakamura
Eric J. Neely
Jason S. Rockel
Tatiana Oussenko
Puzheng Zhang
Mohit Kapoor
Andras Nagy

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1559155

518 views

Original Research

Published on 04 Apr 2025

GSDME knockout alleviates hematopoietic stem cell irradiation injury and aggravates myeloid-biased differentiation

in Stem Cell Research

Lulu Su
Yinping Dong
Bowen Guan
Yuquan Wang
Yanhua Lu
Xinyue Wang
Wenxuan Li
Qidong Huo
Aimin Meng
Deguan Li

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1544320

527 views

Original Research

Accepted on 31 Mar 2025

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and implicates cone involvement in retinal organoids

in Stem Cell Research

Cécile Méjécase
Ya Zhou
Nicholas Owen
Pablo Soro-Barrio
Riccardo Cheloni
Neelima Nair
Hajrah Sarkar
Lyes Toualbi
Mariya Moosajee

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1511066

216 views

Original Research

Accepted on 31 Mar 2025

In-vivo and in-vitro therapeutic evaluation of bone marrow-derived mesenchymal stem cells in liver cancer treatment

in Stem Cell Research

Abdur Rahman Johor
A S M Mahadiuzzaman
Abdulaziz Abdullah Alqusayer
Saleh Abdulaziz Alkarim
F A Dain Md Opo

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1521809

144 views

Review

Published on 31 Mar 2025

Application of human cardiac organoids in cardiovascular disease research

in Stem Cell Research

Hongyan Zhang
Peng Qu
Jun Liu
Panke Cheng
Qian Lei

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1564889

967 views

Review

Published on 27 Mar 2025

Mesenchymal stromal/stem cell-derived exosomes as a potential therapeutic approach to osteoarthritis combined with type 2 diabetes mellitus

in Stem Cell Research

Siyi Xie
Meiling Liu
Yajie Kong
Yiming Yang
Ruixue Chen
Yuzhong Wang
Shuxing Cao
Yongzhou Song

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1549096

862 views