Frontiers in Cell and Developmental Biology

Original Research

Published on 06 Feb 2026

Bioinspired artificial nanovesicles engineered from 3D spheroid-cultured UC-MSCs enhance angiogenic activity in vitro: functional proof-of-concept for ischemic applications

in Stem Cell Research

Prakash Gangadaran
Ramya Lakshmi Rajendran
Ji Min Oh
Jaeyoung Son
Chae Moon Hong
Byeong-Cheol Ahn

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1695559

173 views

Original Research

Published on 05 Feb 2026

Stem cell therapy targets THBS1 to reverse endometrial fibrosis

in Stem Cell Research

Xiaochuan Yu
Lijuan Shi
MingBo Qu
Yonggang Zhang
Yating Zhang
Xinyu Xu
Lina Liu
Huanan Wang
Huali Wang

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1766915

262 views

Original Research

Published on 04 Feb 2026

Global clinical trial landscape of stem cell-based therapies for osteoarthritis: trends and translational implications

in Stem Cell Research

Xin Li
Yue Zhao
Dongsheng Guo
Chen Yan
Jian Zhang
Lin Cheng
Yuefu Dong

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1757935

540 views

Editorial

Accepted on 02 Feb 2026

Editorial: Novel Insights into Cellular Mechanisms and Therapies for Tissue Regeneration

in Stem Cell Research

Weiqiang Lan
Yuheng Liu
Zhangheng Huang
Chuan Guo

Frontiers in Cell and Developmental Biology

Original Research

Accepted on 02 Feb 2026

Extracellular Vesicles Modulate Skin Aging Biomarkers in 3D Reconstructed Full-Thickness Skin Model

in Stem Cell Research

YAO TENG
Elias BOU SAMRA
Sarah GIRARDEAU-HUBERT
Richard BETTS
Franck JUCHAUX
Xavier MARAT
Benedicte FALLOU
Lingyan ZHONG
Rodrigo De Vecchi
Nan HUANG

Frontiers in Cell and Developmental Biology

101 views

Review

Published on 02 Feb 2026

Deer antler stem cell-derived exosomes: a regenerative medicine powerhouse from nature’s own repair kit

in Stem Cell Research

Xidong Liu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1672234

661 views

Original Research

Accepted on 30 Jan 2026

Dynamic Activation and Dual Roles of SOX9⁺ Hepatocytes in Liver Regeneration under acute and chronic injuryand Chronic Disease Revealed by Single-Cell Transcriptomics

in Stem Cell Research

Junwei Zhang
Yiyao Xu
Xin Lu

Frontiers in Cell and Developmental Biology

121 views

Review

Published on 30 Jan 2026

Cellular plasticity: a double-edged sword driving malignant transformation and adaptive remodeling in stem cells

in Stem Cell Research

Xue Du
Zhimei Lin
Yijun Zeng
Chunbao Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1752590

489 views

Original Research

Accepted on 29 Jan 2026

Ascorbic Acid enhances in vitro Primordial germ cell-like cell differentiation from mouse ESCs

in Stem Cell Research

Umesh Kumar
Nithyapriya Kumar
P Chandra Shekar
Kumarasamy Thangaraj

Frontiers in Cell and Developmental Biology

271 views

Correction

Accepted on 28 Jan 2026

Correction: A comparative analysis of stem cells derived from young rabbit knee joints: the potentially superior performance of decellularized extracellular matrix pretreated infrapatellar fat pad stem cells on nanofiber scaffolds

in Stem Cell Research

Zhixin Wei
Qingqing Yu
Qingyun Xie
Dongfa Liao
Xue Gou
Song Chen

Frontiers in Cell and Developmental Biology

Review

Published on 28 Jan 2026

Therapeutic value of mesenchymal stem cell-derived extracellular vesicles in hypertrophic and keloid scars: a systematic review and meta-analysis

in Stem Cell Research

Tianhui Zhai
Wanqi Tang
Pengchao Liu
Yakun Liang
Zhihong Ma
Leiqiang Fan

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1739106

572 views

Original Research

Accepted on 27 Jan 2026

CG-RecNet: A Gated and Attention-Fused Deep Learning Framework for Label-Free and Classification of Neural Stem Cell Differentiation via Imaging Flow Cytometry

in Stem Cell Research

Qinzi Li
Fang Liu
JunYu Zhou
XuanJian Zou
ChenLin Gao
JingZe Li

Frontiers in Cell and Developmental Biology

153 views

Hypothesis and Theory

Published on 27 Jan 2026

Altered senescence and mitochondrial transcriptome defines age-related changes in satellite cells

in Stem Cell Research

Fasih A. Rahman
Joe Quadrilatero

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1699206

778 views

Original Research

Accepted on 26 Jan 2026

AI and Big Data driven knowledge mapping of exosome–hydrogel research in orthopedic regeneration and tissue engineering

in Stem Cell Research

Qinghan Li
Liming Lou
Shuaishuai Wang
Minglei Zhang

Frontiers in Cell and Developmental Biology

153 views

Original Research

Published on 23 Jan 2026

BMP and NODAL paracrine signalling regulate the totipotent-like cell state in embryonic stem cells

in Stem Cell Research

Sanidhya Jagdish
Loick Joumier
Sabin Dhakal
Gilberto Duran-Bishop
Mohammed Usama
Mohan Malleshaiah

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1720355

597 views

Review

Published on 23 Jan 2026

Beyond the canonical niche: how astrocytes carried neurogenic potential into the brain parenchyma

in Stem Cell Research

Marco Fogli
Giulia Nato
Paolo Peretto
Annalisa Buffo
Federico Luzzati

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1737065

648 views

Original Research

Published on 22 Jan 2026

Menstrual blood-derived mesenchymal stromal cell secretome modulates macrophage polarization in a preconditioning-dependent manner

in Stem Cell Research

María Ángeles de Pedro
María Pulido
Ana María Marchena
Verónica Álvarez
Francisco Manuel González-Nuño
Witold Szymański
Johanna Pörschke
Silke Reinartz
Johannes Graumann
Elke Pogge von Strandmann

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1691010

562 views

Review

Accepted on 21 Jan 2026

A Novel Paradigm for Chronic Subdural Hematoma: Regenerative Medicine Strategies Targeting the Pathological Microenvironment

in Stem Cell Research

Zhijian Xu
Yang Song
Guifang Zheng
Huahui Chen
Xing Wan
Hu Xu
Yutiao Xu
Jian Wang
Minfeng Tong
Qi Tu

Frontiers in Cell and Developmental Biology

155 views

Original Research

Published on 21 Jan 2026

Microgravity-induced transcriptional reprogramming in embryonic chicken limb bud-derived chondrogenic cultures

in Stem Cell Research

Patrik Kovács
Zhangzheng Wang
Tibor Hajdú
Krisztián Zoltán Juhász
Éva Katona
Roland Takács
Judit Vágó
Róza Zákány
Szilárd Póliska
Péter Szentesi

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1746313

524 views

Original Research

Published on 20 Jan 2026

Single-cell RNA sequencing revealed cell heterogeneity in sagittal suture mesenchyme

in Stem Cell Research

Chengyan Ren
Kai Sun
Ran Wu
Chenxin Geng
Jiangping Chen
Hu Zhao
Weihui Chen

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2026.1725375

590 views

Original Research

Accepted on 19 Jan 2026

Divergent functions of the RNA-binding protein, Mei-P26 in germline and somatic lineages of Drosophila testis

in Stem Cell Research

Shallinie THANGADURAI
Elena S Pak
Alexander K. Murashov

Frontiers in Cell and Developmental Biology

142 views

Original Research

Published on 15 Jan 2026

Adiponectin receptor T-cadherin emerges as a novel regulator of adipose stem cell quiescence and adipogenesis

in Stem Cell Research

V. Yu Sysoeva
M. S. Arbatsky
K. Yu Kulebyakin
P. A. Tyurin-Kuzmin
E. V. Semina
P. S. Klimovich
I. B. Brodsky
D. D. Romashin
A. F. Altyeva
N. S. Voloshin

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1734183

1,173 views

Original Research

Published on 14 Jan 2026

Degradable fibrin hydrogels for transplantation of iPSC-derived retinal pigment epithelial cell monolayers

in Stem Cell Research

Alan D. Marmorstein
Brittni A. Scruggs
Travis Knudsen
Matthew Hill
Francesca N. Kopp
Emma Trncic
David Korda
Evan Atherton
Aubrey Berger
Silvia C. Finnemann

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1739620

900 views

Methods

Published on 14 Jan 2026

Generation of xenobiotic free retinofugal assembloids

in Stem Cell Research

Michael H. Hayes
Maria F. Valdes Michel
Markus H. Kuehn
Randy H. Kardon
Oliver W. Gramlich

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1746709

863 views

1,779 articles

articles

Bioinspired artificial nanovesicles engineered from 3D spheroid-cultured UC-MSCs enhance angiogenic activity in vitro: functional proof-of-concept for ischemic applications

Stem cell therapy targets THBS1 to reverse endometrial fibrosis

Global clinical trial landscape of stem cell-based therapies for osteoarthritis: trends and translational implications

Editorial: Novel Insights into Cellular Mechanisms and Therapies for Tissue Regeneration

Extracellular Vesicles Modulate Skin Aging Biomarkers in 3D Reconstructed Full-Thickness Skin Model

Deer antler stem cell-derived exosomes: a regenerative medicine powerhouse from nature’s own repair kit

Dynamic Activation and Dual Roles of SOX9⁺ Hepatocytes in Liver Regeneration under acute and chronic injuryand Chronic Disease Revealed by Single-Cell Transcriptomics

Cellular plasticity: a double-edged sword driving malignant transformation and adaptive remodeling in stem cells

Ascorbic Acid enhances in vitro Primordial germ cell-like cell differentiation from mouse ESCs

Correction: A comparative analysis of stem cells derived from young rabbit knee joints: the potentially superior performance of decellularized extracellular matrix pretreated infrapatellar fat pad stem cells on nanofiber scaffolds

Therapeutic value of mesenchymal stem cell-derived extracellular vesicles in hypertrophic and keloid scars: a systematic review and meta-analysis

CG-RecNet: A Gated and Attention-Fused Deep Learning Framework for Label-Free and Classification of Neural Stem Cell Differentiation via Imaging Flow Cytometry

Altered senescence and mitochondrial transcriptome defines age-related changes in satellite cells

AI and Big Data driven knowledge mapping of exosome–hydrogel research in orthopedic regeneration and tissue engineering

BMP and NODAL paracrine signalling regulate the totipotent-like cell state in embryonic stem cells

Beyond the canonical niche: how astrocytes carried neurogenic potential into the brain parenchyma

Menstrual blood-derived mesenchymal stromal cell secretome modulates macrophage polarization in a preconditioning-dependent manner

A Novel Paradigm for Chronic Subdural Hematoma: Regenerative Medicine Strategies Targeting the Pathological Microenvironment

Microgravity-induced transcriptional reprogramming in embryonic chicken limb bud-derived chondrogenic cultures

Single-cell RNA sequencing revealed cell heterogeneity in sagittal suture mesenchyme

Divergent functions of the RNA-binding protein, Mei-P26 in germline and somatic lineages of Drosophila testis

Adiponectin receptor T-cadherin emerges as a novel regulator of adipose stem cell quiescence and adipogenesis

Degradable fibrin hydrogels for transplantation of iPSC-derived retinal pigment epithelial cell monolayers

Generation of xenobiotic free retinofugal assembloids