Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Original Research

Published on 03 Oct 2024

Stemona alkaloid derivative induce ferroptosis of colorectal cancer cell by mediating carnitine palmitoyltransferase 1

in Medicinal and Pharmaceutical Chemistry

He Yang
Ling Wang
Mengcheng Zhang
Xingkang Wu
Zhenyu Li
Kaiqing Ma

Frontiers in Chemistry

doi 10.3389/fchem.2024.1478674

1,756 views
1 citation

Review

Published on 26 Sep 2024

Venom-derived peptides for breaking through the glass ceiling of drug development

in Medicinal and Pharmaceutical Chemistry

Lou Freuville
Chloé Matthys
Loïc Quinton
Jean-Pierre Gillet

Frontiers in Chemistry

doi 10.3389/fchem.2024.1465459

5,951 views
1 citation

Original Research

Published on 24 Sep 2024

Topological indices based VIKOR assisted multi-criteria decision technique for lung disorders

in Medicinal and Pharmaceutical Chemistry

Tahreem Ashraf
Nazeran Idrees

Frontiers in Chemistry

doi 10.3389/fchem.2024.1407911

1,586 views
3 citations

Original Research

Published on 20 Sep 2024

Structure-based virtual screening towards the discovery of novel thrombin inhibitors with Anti-HCC activities

in Medicinal and Pharmaceutical Chemistry

Xiaoxi Zhang
Xumei Zheng
Chun Han
Lintao Wu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1451574

1,319 views
2 citations

Editorial

Published on 19 Sep 2024

Editorial: Advances in wound repair and regeneration: novel materials, targets and applications

in Medicinal and Pharmaceutical Chemistry

Xinwei Cheng
Jia Zhou

Frontiers in Chemistry

doi 10.3389/fchem.2024.1487091

956 views

Editorial

Published on 17 Sep 2024

Editorial: Novel compounds from chemistry to druggable candidates

in Medicinal and Pharmaceutical Chemistry

Pete Rose
Jawad Nasim
Yi-Zhun Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1494407

1,220 views

Original Research

Published on 13 Sep 2024

Phytochemical analysis, identification of bioactive compounds using GC-MS, in vitro and in silico hypoglycemic potential, in vitro antioxidant potential, and in silico ADME analysis of Chlorophytum comosum root and leaf

in Medicinal and Pharmaceutical Chemistry

P. Kavya
R. C. Theijeswini
M. Gayathri

Frontiers in Chemistry

doi 10.3389/fchem.2024.1458505

3,484 views
4 citations

Original Research

Published on 13 Sep 2024

Phytochemical profile, physicochemical, antioxidant and antimicrobial properties of Juniperus phoenicea and Tetraclinis articulate: in vitro and in silico approaches

in Medicinal and Pharmaceutical Chemistry

Ayoub Asbabou
Touijer Hanane
Aman Allah Gourich
Farhan Siddique
Aziz Drioiche
Firdaous Remok
Soukaina Saidi
Imad Adadi
Hamid Khamar
Khalid S. Almaary

Frontiers in Chemistry

doi 10.3389/fchem.2024.1397961

3,212 views
2 citations

Original Research

Published on 10 Sep 2024

Salsoline derivatives, genistein, semisynthetic derivative of kojic acid, and naringenin as inhibitors of A42R profilin-like protein of monkeypox virus: in silico studies

in Medicinal and Pharmaceutical Chemistry

Mohamed Chebaibi
Mohammed Bourhia
Fatima ez-zahra Amrati
Meryem Slighoua
Ibrahim Mssillou
Mourad A. M. Aboul-Soud
Asaad Khalid
Rym Hassani
Dalila Bousta
Sanae Achour

Frontiers in Chemistry

doi 10.3389/fchem.2024.1445606

2,758 views
5 citations

Original Research

Published on 06 Sep 2024

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

in Medicinal and Pharmaceutical Chemistry

Lamya H. Al-Wahaibi
Hesham A. Abou-Zied
Mostafa H. Abdelrahman
Martha M. Morcoss
Laurent Trembleau
Bahaa G. M. Youssif
Stefan Bräse

Frontiers in Chemistry

doi 10.3389/fchem.2024.1432920

2,796 views
4 citations

Original Research

Published on 30 Aug 2024

Design and synthesis of new 1,2,4-oxadiazole/quinazoline-4-one hybrids with antiproliferative activity as multitargeted inhibitors

in Medicinal and Pharmaceutical Chemistry

Amira M. Mohamed
Ola M. F. Abou-Ghadir
Yaser A. Mostafa
Kholood A. Dahlous
Stefan Bräse
Bahaa G. M. Youssif

Frontiers in Chemistry

doi 10.3389/fchem.2024.1447618

21,182 views
7 citations

Original Research

Published on 21 Aug 2024

Molecular insights into kaempferol derivatives as potential inhibitors for CDK2 in colon cancer: pharmacophore modeling, docking, and dynamic analysis

in Medicinal and Pharmaceutical Chemistry

Fei Xing
Zhicheng Wang
Noor Bahadar
Can Wang
Xu-Dong Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1440196

2,505 views
3 citations

Original Research

Published on 16 Aug 2024

Bactericidal, anti-hemolytic, and anticancerous activities of phytofabricated silver nanoparticles of glycine max seeds

in Medicinal and Pharmaceutical Chemistry

K. B. Vijendra Kumar
Kavitha Raj Varadaraju
Prasanna D. Shivaramu
C. M. Hemanth Kumar
H. R. Prakruthi
B. M. Chandra Shekara
Bhargav Shreevatsa
Tanveer A. Wani
K. C. Prakasha
Shiva Prasad Kollur

Frontiers in Chemistry

doi 10.3389/fchem.2024.1427797

2,837 views
3 citations

Original Research

Published on 13 Aug 2024

Structural analogs of 2-(4-fluorophenyl)-6-methyl-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine for targeting Candida albicans non-essential stress kinase Yck2 through protein-ligand binding and dynamics analysis

in Medicinal and Pharmaceutical Chemistry

Ahmed M. Hassan
Aiah M. Khateb
Safaa A. Turkistani
Meshari M. Alhamdan
Raed M. Garout
Vivek Dhar Dwivedi
Esam I. Azhar

Frontiers in Chemistry

doi 10.3389/fchem.2024.1430157

3,631 views
4 citations

Original Research

Published on 12 Aug 2024

Computational insights into rational design and virtual screening of pyrazolopyrimidine derivatives targeting Janus kinase 3 (JAK3)

in Medicinal and Pharmaceutical Chemistry

Abdelmoujoud Faris
Ivana Cacciatore
Radwan Alnajjar
Adnane Aouidate
Mohammed H. AL Mughram
Menana Elhallaoui

Frontiers in Chemistry

doi 10.3389/fchem.2024.1425220

5,649 views
2 citations

Original Research

Published on 08 Aug 2024

Mechanism investigation of highly selective inhibitors toward phosphodiesterase 5 and 6 via the in vitro calculation and simulation

in Medicinal and Pharmaceutical Chemistry

Lihang Qu
Kaijian Sun
Zhouyu Jiang
Ting Wang
Linlin Chen
Chunjian Shen
Ruidong Gu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1400886

1,899 views
1 citation