Frontiers in Chemistry | Medicinal and Pharmaceutical Chemistry

Original Research

Published on 16 Oct 2024

Synthesis and antibacterial potential of novel thymol derivatives against methicillin-resistant Staphylococcus aureus and P. aeruginosa pathogenic bacteria

in Medicinal and Pharmaceutical Chemistry

Ashutosh Shahi
Rakshit Manhas
Srija Bhattacharya
Arti Rathore
Puneet Kumar
Jayanta Samanta
Manish Kumar Sharma
Avisek Mahapa
Prasoon Gupta
Jasha Momo H. Anal

Frontiers in Chemistry

doi 10.3389/fchem.2024.1482852

2,279 views
3 citations

Original Research

Published on 15 Oct 2024

Sustainable synthesis of silver nanoparticles from Azadirachta indica: antimicrobial, antioxidant and in silico analysis for periodontal treatment

in Medicinal and Pharmaceutical Chemistry

Binapani Barik
Bhabani Sankar Satapathy
Gurudutta Pattnaik
Desai Vijay Bhavrao
Krishna Prasad Shetty

Frontiers in Chemistry

doi 10.3389/fchem.2024.1489253

1,938 views
2 citations

Original Research

Published on 08 Oct 2024

Computational exploration of acefylline derivatives as MAO-B inhibitors for Parkinson’s disease: insights from molecular docking, DFT, ADMET, and molecular dynamics approaches

in Medicinal and Pharmaceutical Chemistry

Ali Irfan
Ameer Fawad Zahoor
Yassir Boulaamane
Sadia Javed
Huma Hameed
Amal Maurady
Muhammed Tilahun Muhammed
Sajjad Ahmad
Aamal A. Al-Mutairi
Irum Shahzadi

Frontiers in Chemistry

doi 10.3389/fchem.2024.1449165

2,741 views
1 citation

Original Research

Published on 08 Oct 2024

Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP

in Medicinal and Pharmaceutical Chemistry

William J. Netzer
Anjana Sinha
Mondana Ghias
Emily Chang
Katherina Gindinova
Emily Mui
Ji-Seon Seo
Subhash C. Sinha

Frontiers in Chemistry

doi 10.3389/fchem.2024.1381205

1,056 views

Original Research

Published on 03 Oct 2024

Stemona alkaloid derivative induce ferroptosis of colorectal cancer cell by mediating carnitine palmitoyltransferase 1

in Medicinal and Pharmaceutical Chemistry

He Yang
Ling Wang
Mengcheng Zhang
Xingkang Wu
Zhenyu Li
Kaiqing Ma

Frontiers in Chemistry

doi 10.3389/fchem.2024.1478674

1,516 views
1 citation

Review

Published on 26 Sep 2024

Venom-derived peptides for breaking through the glass ceiling of drug development

in Medicinal and Pharmaceutical Chemistry

Lou Freuville
Chloé Matthys
Loïc Quinton
Jean-Pierre Gillet

Frontiers in Chemistry

doi 10.3389/fchem.2024.1465459

5,104 views
1 citation

Original Research

Published on 24 Sep 2024

Topological indices based VIKOR assisted multi-criteria decision technique for lung disorders

in Medicinal and Pharmaceutical Chemistry

Tahreem Ashraf
Nazeran Idrees

Frontiers in Chemistry

doi 10.3389/fchem.2024.1407911

1,306 views
3 citations

Original Research

Published on 20 Sep 2024

Structure-based virtual screening towards the discovery of novel thrombin inhibitors with Anti-HCC activities

in Medicinal and Pharmaceutical Chemistry

Xiaoxi Zhang
Xumei Zheng
Chun Han
Lintao Wu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1451574

1,121 views
2 citations

Editorial

Published on 19 Sep 2024

Editorial: Advances in wound repair and regeneration: novel materials, targets and applications

in Medicinal and Pharmaceutical Chemistry

Xinwei Cheng
Jia Zhou

Frontiers in Chemistry

doi 10.3389/fchem.2024.1487091

803 views

Editorial

Published on 17 Sep 2024

Editorial: Novel compounds from chemistry to druggable candidates

in Medicinal and Pharmaceutical Chemistry

Pete Rose
Jawad Nasim
Yi-Zhun Zhu

Frontiers in Chemistry

doi 10.3389/fchem.2024.1494407

1,031 views

Original Research

Published on 13 Sep 2024

Phytochemical analysis, identification of bioactive compounds using GC-MS, in vitro and in silico hypoglycemic potential, in vitro antioxidant potential, and in silico ADME analysis of Chlorophytum comosum root and leaf

in Medicinal and Pharmaceutical Chemistry

P. Kavya
R. C. Theijeswini
M. Gayathri

Frontiers in Chemistry

doi 10.3389/fchem.2024.1458505

2,890 views
2 citations

Original Research

Published on 13 Sep 2024

Phytochemical profile, physicochemical, antioxidant and antimicrobial properties of Juniperus phoenicea and Tetraclinis articulate: in vitro and in silico approaches

in Medicinal and Pharmaceutical Chemistry

Ayoub Asbabou
Touijer Hanane
Aman Allah Gourich
Farhan Siddique
Aziz Drioiche
Firdaous Remok
Soukaina Saidi
Imad Adadi
Hamid Khamar
Khalid S. Almaary

Frontiers in Chemistry

doi 10.3389/fchem.2024.1397961

2,888 views
2 citations

Original Research

Published on 10 Sep 2024

Salsoline derivatives, genistein, semisynthetic derivative of kojic acid, and naringenin as inhibitors of A42R profilin-like protein of monkeypox virus: in silico studies

in Medicinal and Pharmaceutical Chemistry

Mohamed Chebaibi
Mohammed Bourhia
Fatima ez-zahra Amrati
Meryem Slighoua
Ibrahim Mssillou
Mourad A. M. Aboul-Soud
Asaad Khalid
Rym Hassani
Dalila Bousta
Sanae Achour

Frontiers in Chemistry

doi 10.3389/fchem.2024.1445606

2,378 views
5 citations

Original Research

Published on 06 Sep 2024

Design and synthesis new indole-based aromatase/iNOS inhibitors with apoptotic antiproliferative activity

in Medicinal and Pharmaceutical Chemistry

Lamya H. Al-Wahaibi
Hesham A. Abou-Zied
Mostafa H. Abdelrahman
Martha M. Morcoss
Laurent Trembleau
Bahaa G. M. Youssif
Stefan Bräse

Frontiers in Chemistry

doi 10.3389/fchem.2024.1432920

2,083 views
4 citations

Original Research

Published on 30 Aug 2024

Design and synthesis of new 1,2,4-oxadiazole/quinazoline-4-one hybrids with antiproliferative activity as multitargeted inhibitors

in Medicinal and Pharmaceutical Chemistry

Amira M. Mohamed
Ola M. F. Abou-Ghadir
Yaser A. Mostafa
Kholood A. Dahlous
Stefan Bräse
Bahaa G. M. Youssif

Frontiers in Chemistry

doi 10.3389/fchem.2024.1447618

19,529 views
6 citations

Original Research

Published on 21 Aug 2024

Molecular insights into kaempferol derivatives as potential inhibitors for CDK2 in colon cancer: pharmacophore modeling, docking, and dynamic analysis

in Medicinal and Pharmaceutical Chemistry

Fei Xing
Zhicheng Wang
Noor Bahadar
Can Wang
Xu-Dong Wang

Frontiers in Chemistry

doi 10.3389/fchem.2024.1440196

2,157 views
3 citations