Frontiers in Endocrinology

Original Research

Published on 02 Jan 2026

Sex-specific effects of peptidyl arginine deiminase 4 deficiency in the cafeteria diet-induced obesity-associated metabolic complications

in Obesity

Andrej Feješ
Emil Bečka
Ivana Feješ Slivková
Kristína Macáková
Emőke Šteňová
Michal Pastorek
Peter Celec
Roman Gardlík
Katarína Šebeková
Veronika Borbélyová

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1694559

1,541 views

Original Research

Published on 08 Dec 2025

A contribution-interpretable belief rule base model for obesity risk prediction using physical indicators and dietary habits

in Obesity

Fanxu Wei
Li Jiang
Hailong Zhu
Yinling Mao

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1706780

989 views

Systematic Review

Published on 05 Dec 2025

BMI is associated with sperm quality and sex hormones in men: a meta-analysis

in Obesity

Fengming Ji
Bing Yan
Chenghao Zhanghuang
Chengchuang Wu
Jinshuan Dai
Shengde Wu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1714019

1,649 views

Original Research

Published on 02 Dec 2025

Lipomas are associated with a higher prevalence of metabolic syndrome components: a multicenter cross-sectional study

in Obesity

Ori Berger
Shaked Menashe
Shiri Damti Geva
Reychel Yakubov
Maor Ben Yehuda
Mor Peleg
Ran Talisman

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1721570

2,963 views

Systematic Review

Published on 27 Nov 2025

The relationship between childhood obesity and male puberty development: a systematic review and meta-analysis

in Obesity

Wenhua Feng
Chaonan Ren

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1711557

1,982 views

Editorial

Published on 25 Nov 2025

Editorial: Physical activity behavior, obesity, and stress as crucial sources of health issues in stressful occupations, volume II

in Obesity

Filip Kukić
Katie M. Heinrich

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1742390

583 views

Original Research

Published on 25 Nov 2025

Palmitic acid differently modulates extracellular vesicles and cellular fatty acid composition of SGBS adipocytes without impairing their insulin signaling

in Obesity

Domenico Sergi
Sharon Angelini
Fabiola Castaldo
Marco Beccaria
Carlo Bellinghieri
Flavio Franchina
Alice Omenetto
Gabriella Stifani
Sefora Del Mastro
Stefania Merighi

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1699831

2,007 views

Original Research

Published on 20 Nov 2025

Plasma oxytocin and leptin in relation to disordered eating: evidence from non-linear modeling across metabolic obesity phenotypes

in Obesity

Sevara Anvarova
Gulchekhra Narimova
Anna Aliyeva
Zamira Khalimova
Khurshida Nasirova

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1693509

1,035 views

Original Research

Published on 18 Nov 2025

Hepatokines modulation in obesity: which exercise training model is better in men with obesity?

in Obesity

Ali Ataeinosrat
Hossein Abednatanzi
Shohreh Hajesfandiari
Maryam N. AL Nasser
Marjan Mansouri Dara
Parvin Farzanegi
Mahnoosh Salari Nahand
Abdullah Almaqhawi
Niloofar Karimi
Behnam Bagherzadeh-Rahmani

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1560453

1,808 views

Original Research

Published on 10 Nov 2025

Associations between body composition, hydration status, and sleep architecture in obstructive sleep apnea

in Obesity

Ya-Min Chuang
Wen-Te Liu
Cheng-Yu Tsai
Yi-Chih Lin
Kin Fai Ho
Kai-Jen Chuang
Hsiao-Chi Chuang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1666026

1,817 views

Systematic Review

Published on 04 Nov 2025

Metabolic syndrome components individually worsen the outcome of acute pancreatitis: a systematic review and meta-analysis

in Obesity

Dalma Dobszai
Mahmoud Obeidat
Eszter Ágnes Szalai
Dániel Sándor Veres
Luca Havelda
Renáta Papp
Alim Choi
Bettina Csilla Budai
Dominika Csajbók
Péter Hegyi

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1690754

1,898 views

Original Research

Published on 31 Oct 2025

From awareness to action: evolving endocrinologist practices in obesity treatment in Italy

in Obesity

Marco Chianelli
Luca Busetto
Roberto Attanasio
Rinaldo Guglielmi
Renato Cozzi
Franco Grimaldi
Andrea Frasoldati
Agnese Persichetti
Enrico Papini
Antonio Nicolucci

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1705670

1,283 views
1 citation

Original Research

Published on 29 Oct 2025

Pdgfrα deficiency in islet β-cells up-regulates apoptosis of beta-cells and disturbs glucose metabolism in B6 mice

in Obesity

Luyao Zhang
Yanpeng Xing
Pai Wang
Jianlei Gu
Jian Peng
Juan Huang
James Alexander Pearson
Youjia Hu
Hongyu Zhao
F. Susan Wong

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1630979

1,723 views

Original Research

Published on 29 Oct 2025

Increased spontaneous physical activity in female MEST-deficient mice protects against diet-induced obesity

in Obesity

Rea Victoria P. Anunciado-Koza
M. Elena Martinez
Victoria DeMambro
Arturo Hernandez
Robert A. Koza

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1680158

1,456 views
1 citation

Original Research

Published on 21 Oct 2025

Obesity results in lower integrin expression in women with polycystic ovarian syndrome during the window of implantation

in Obesity

Fazilah Abdul Hamid
Mohd Helmy Mokhtar
Abdul Kadir Abdul Karim
Mohd Faizal Ahmad
Nor Haslinda Abd Aziz
Azantee Yazmie Abdul Wahab
Muhammad Azrai Abu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1590716

1,453 views

Review

Published on 17 Oct 2025

Metabolic impact of endogenously produced estrogens by adipose tissue in females and males across the lifespan

in Obesity

Angel A. Lee
Laura J. Den Hartigh

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682231

4,352 views
2 citations

Original Research

Published on 17 Oct 2025

Extreme gradient boosting using conventional parameters accurately predicts insulin sensitivity in young and middle-aged Japanese persons

in Obesity

Norimitsu Murai
Naoko Saito
Sayuri Nii
Hiroto Nishikawa
Eriko Kodama
Tatsuya Iida
Hideyuki Imai
Mai Hashizume
Rie Tadokoro
Chiho Sugisawa

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1661376

1,092 views

Review

Published on 14 Oct 2025

Analyzing and evaluating the metabolic and endocrine characteristics between lean and obese patients with polycystic ovary syndrome: a systemic review and meta-analysis

in Obesity

Caiyu Zheng
Yuhao Lin
Zhijun Zhang
Jiawen Ye
Yanmei Lin
Jianqing Tian

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1680685

3,149 views
1 citation

Original Research

Published on 10 Oct 2025

Impact of the new EASO obesity definition on the detection of atheromatosis in subjects with low-to-moderate cardiovascular risk

in Obesity

Josep León-Mengíbar
Marcelino Bermúdez-López
José Manuel Valdivielso
Reinald Pamplona
Gerard Torres
Dídac Mauricio
Eva Castro-Boqué
Elvira Fernández
Assumpta Caixàs
Marta Bueno

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1689960

2,235 views

Original Research

Published on 10 Oct 2025

Temporal trends in cancer mortality attributable to high BMI in Asia: an age-period-cohort analysis based on GBD 1992–2021

in Obesity

Minguang Huang
Liejiong Wang
Ying Lou
Zhaoqi Qiu
Shengjian Yu
Feng Xuan

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1691487

2,011 views
2 citations

Original Research

Published on 10 Oct 2025

Obesity indices and their sociodemographic, lifestyle, and social isolation correlates in a large Spanish working population

in Obesity

Pere Riutord-Sbert
Pedro Juan Tárraga López
Ángel Arturo López-González
Irene Coll Campayo
Carla Busquets-Cortés
José Ignacio Ramírez Manent

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1695705

2,449 views

Review

Published on 09 Oct 2025

The role of exercise and nutrition in modulating inflammatory cytokines activity for obesity management

in Obesity

Sara Sobreviela Sánchez
Ravi Giusfredi Quevedo
Tiago Fernandes
Guilherme Wesley Peixoto da Fonseca

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1618360

3,446 views
2 citations

Original Research

Published on 08 Oct 2025

Transcriptomic elucidation of Dahuang-Huanglian in promoting white adipose browning in high-fat diet-induced obese rats

in Obesity

Ruiyao Zhang
Yu Zhang
Xi Xi
Pengcheng Du
Chao Guo
Yanying Zhang
Bing Song
Xiaoyan Xu
Zhitao Ni
Yongfeng Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1652703

2,439 views

Correction

Published on 02 Oct 2025

Correction: Pharmacotherapy for obesity: are we ready to select, tailor and combine pharmacotherapy to achieve more ambitious goals?

in Obesity

Nele Steenackers
Julia Toumassian
Ellen Deleus
Ann Mertens
Matthias Lannoo
Sofia Pazmino
Amar Daniël Emanuel van Laar
Bart Van der Schueren
Roman Vangoitsenhoven

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1656611

1,850 views

1,172 articles

articles

Sex-specific effects of peptidyl arginine deiminase 4 deficiency in the cafeteria diet-induced obesity-associated metabolic complications

A contribution-interpretable belief rule base model for obesity risk prediction using physical indicators and dietary habits

BMI is associated with sperm quality and sex hormones in men: a meta-analysis

Lipomas are associated with a higher prevalence of metabolic syndrome components: a multicenter cross-sectional study

The relationship between childhood obesity and male puberty development: a systematic review and meta-analysis

Editorial: Physical activity behavior, obesity, and stress as crucial sources of health issues in stressful occupations, volume II

Palmitic acid differently modulates extracellular vesicles and cellular fatty acid composition of SGBS adipocytes without impairing their insulin signaling

Plasma oxytocin and leptin in relation to disordered eating: evidence from non-linear modeling across metabolic obesity phenotypes

Hepatokines modulation in obesity: which exercise training model is better in men with obesity?

Associations between body composition, hydration status, and sleep architecture in obstructive sleep apnea

Metabolic syndrome components individually worsen the outcome of acute pancreatitis: a systematic review and meta-analysis

From awareness to action: evolving endocrinologist practices in obesity treatment in Italy

Pdgfrα deficiency in islet β-cells up-regulates apoptosis of beta-cells and disturbs glucose metabolism in B6 mice

Increased spontaneous physical activity in female MEST-deficient mice protects against diet-induced obesity

Obesity results in lower integrin expression in women with polycystic ovarian syndrome during the window of implantation

Metabolic impact of endogenously produced estrogens by adipose tissue in females and males across the lifespan

Extreme gradient boosting using conventional parameters accurately predicts insulin sensitivity in young and middle-aged Japanese persons

Analyzing and evaluating the metabolic and endocrine characteristics between lean and obese patients with polycystic ovary syndrome: a systemic review and meta-analysis

Impact of the new EASO obesity definition on the detection of atheromatosis in subjects with low-to-moderate cardiovascular risk

Temporal trends in cancer mortality attributable to high BMI in Asia: an age-period-cohort analysis based on GBD 1992–2021

Obesity indices and their sociodemographic, lifestyle, and social isolation correlates in a large Spanish working population

The role of exercise and nutrition in modulating inflammatory cytokines activity for obesity management

Transcriptomic elucidation of Dahuang-Huanglian in promoting white adipose browning in high-fat diet-induced obese rats

Correction: Pharmacotherapy for obesity: are we ready to select, tailor and combine pharmacotherapy to achieve more ambitious goals?