Your new experience awaits. Try the new design now and help us make it even better

MINI REVIEW article

Front. Food Sci. Technol.

Sec. Food Biotechnology

Volume 5 - 2025 | doi: 10.3389/frfst.2025.1692683

This article is part of the Research TopicInnovative Microbiota Applications in the Fermentation IndustryView all articles

Current research status and trends in the bioactivity of postbiotics

Provisionally accepted
Xueling  ChenXueling Chen1Can  YuanCan Yuan2Jiang  HeJiang He3*Wanwu  LiWanwu Li4Cheng  LiaoCheng Liao5*
  • 1Yibin Vocational and Technical College, Yibin, China
  • 2Sichuan Tourism University, Chengdu, China
  • 3Chengdu Normal University, Chengdu, China
  • 4Yibin Branch of Sichuan Tobacco Corporation, Yibin, China
  • 5Nanguang Primary School in Xuzhou District of Yibin City, Yibin, China

The final, formatted version of the article will be published soon.

Postbiotics have similar bioactivity to probiotics and are safer and more stable. The results indicate that postbiotics exert their effects through direct (antibacterial, antioxidant, immune regulatory) and indirect (regulating microbial homeostasis and metabolic pathways) mechanisms. In the field of animals, postbiotics can enhance the disease resistance of aquatic animals, improve the intestinal health and meat quality of broiler chickens, and promote nutrient absorption in ruminant animals. In the field of humans, postbiotics exhibit potential for anti-allergy, prevention of respiratory or digestive tract infections, adjuvant therapy for anti-cancer, and improvement of liver cirrhosis. Meanwhile, postbiotics have been applied in the research and development of medical preparations and functional foods, but the mechanism of action still needs to be further explored. Compared to probiotics, postbiotics do not require live bacteria to produce health benefits and have advantages such as high safety, easy storage, and convenient production. In the future, postbiotics have broad prospects in the fields of functional foods with unique flavors and nutritional health benefits, and disease prevention and control.

Keywords: Postbiotics, Probiotics, Bioactivity, disease prevention, Functional Food

Received: 26 Aug 2025; Accepted: 04 Sep 2025.

Copyright: © 2025 Chen, Yuan, He, Li and Liao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence:
Jiang He, Chengdu Normal University, Chengdu, China
Cheng Liao, Nanguang Primary School in Xuzhou District of Yibin City, Yibin, China

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.