Frontiers in Immunology | Immunological Tolerance and Regulation

Opinion

Published on 23 Jul 2025

‘Immune reset plus’: the case for combining immunotherapies to maintain self-tolerance in autoimmune diseases

in Immunological Tolerance and Regulation

Fabrina Gaspal
Parth Narendran
Sky T. H. Ng
Michael J. Price
David C. Wraith

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634090

3,660 views
1 citation

Mini Review

Published on 22 Jul 2025

Anti-IgE therapy versus allergen-specific immunotherapy for food allergy: weighing the pros and cons

in Immunological Tolerance and Regulation

Michael D. Kulis
Jessica R. Humphrey
James W. Krempski
Edwin H. Kim
Johanna M. Smeekens

Frontiers in Immunology

doi 10.3389/fimmu.2025.1617153

6,121 views
3 citations

Review

Published on 17 Jul 2025

Macrophages in chronic infections: regulation and remodeling

in Immunological Tolerance and Regulation

Hongle Cui
Min Wang
Sitan Jiao
Sirui Tian
Hui Liu
Bo Luo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594988

3,154 views
2 citations

Review

Published on 14 Jul 2025

Decidual macrophage subsets and polarization puzzle during the human early pregnancy

in Immunological Tolerance and Regulation

Huiling Liu
Liping Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1610891

2,751 views
3 citations

Original Research

Published on 14 Jul 2025

Interferon Regulatory Factor 4 dose-dependently controls peripheral Treg cell differentiation and homeostasis by modulating chromatin accessibility in mice

in Immunological Tolerance and Regulation

Leonie Caroline Voß
Constantin Schmidt
Aenne Harberts
Michael Spohn
Peter Bradtke
Alina Borchers
Stefanie Fertig
Joanna Schmid
Friedrich Koch-Nolte
Christian F. Krebs

Frontiers in Immunology

doi 10.3389/fimmu.2025.1604888

3,458 views

Review

Published on 07 Jul 2025

Platelets in infection: intrinsic roles and functional outcomes

in Immunological Tolerance and Regulation

Yuwei Hu
Shuchang Dai
Congchao Qiao
Yifan Ye
Junyi Ren
Kai Wang
Ling Li
Zhong Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1616783

4,348 views
4 citations

Original Research

Published on 07 Jul 2025

LYN and CYBB are pivotal immune and inflammatory genes as diagnostic biomarkers in recurrent spontaneous abortion

in Immunological Tolerance and Regulation

Zhuna Wu
Qiuya Lin
Zhimei Zhou
Yajing Xie
Li Huang
Liying Sheng
Qirong Shi
Yumin Ke

Frontiers in Immunology

doi 10.3389/fimmu.2025.1568536

3,738 views
1 citation

Editorial

Published on 02 Jul 2025

Editorial: Community series in autoantibodies, volume II

in Immunological Tolerance and Regulation

Aikaterini Kyriakou
Aikaterini Patsatsi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644057

1,588 views

Correction

Published on 23 Jun 2025

Correction: Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology

in Immunological Tolerance and Regulation

Xinyao Zhou
Wuqian Wang
Luan Chen
Yingjun Yang
Xing Wei
Jia Zhou
Kuan Sun
Ping Tang
Xiaofang Sun
Shengying Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1632381

1,739 views

Review

Published on 19 Jun 2025

Tumor necrosis factor receptor 2 in allergen tolerance: a perspective view

in Immunological Tolerance and Regulation

Guillem Montamat-Garcia
Murilo Luiz Bazon
Agnieszka Demczuk
Cathy Leonard
Markus Ollert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1613719

3,510 views

Original Research

Published on 18 Jun 2025

IL-24 producing regulatory T and B lymphocytes in endometriosis

in Immunological Tolerance and Regulation

Anna Ewa Kedzierska
Daria Lorek
Anna Slawek
Mikolaj Karmowski
Aleksandra Kalota
Jaroslaw Pajak
Agnieszka Chrobak
Krzysztof Grzymajlo
Anna Chelmonska-Soyta

Frontiers in Immunology

doi 10.3389/fimmu.2025.1582762

3,269 views
1 citation

Original Research

Published on 17 Jun 2025

Differential metabolic pathways underlie THC- and CBD-mediated inhibition of B-cell activation in both young and aged mice

in Immunological Tolerance and Regulation

Zhanna Yekhtin
Dmytro Petukhov
Iman Khuja
Natalya M. Kogan
Reuven Or
Osnat Almogi-Hazan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1605474

3,017 views
1 citation

Original Research

Published on 11 Jun 2025

Expression and correlation of SOCS3 and Eotaxin mRNA and proteins levels in nasal mucosal tissue of allergic rhinitis patients

in Immunological Tolerance and Regulation

Zhaopeng Kang
Lian Xu
Ping Ai
Wei Qu
Tang Li
Lixin Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1561650

1,955 views

Editorial

Published on 10 Jun 2025

Editorial: Host-pathogen interactions during pregnancy: mechanisms of maternal and fetal immunity

in Immunological Tolerance and Regulation

Yael Alippe
Vanesa Hauk
Gil Mor
Daiana M. Vota

Frontiers in Immunology

doi 10.3389/fimmu.2025.1629528

1,523 views

Original Research

Published on 06 Jun 2025

Insights into regulatory T-cell and type-I interferon roles in determining abacavir-induced hypersensitivity or immune tolerance

in Immunological Tolerance and Regulation

Marco Cardone
Hratch M. Baghdassarian
Maryam Khalaj
Kirthiram Krishnaveni Sivakumar
SuJin Hwang
Sintayehu Gebreyohannes
Kazuyo Takeda
Yura Jang
Nathan E. Lewis
Michael A. Norcross

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612451

3,892 views
2 citations

Review

Published on 04 Jun 2025

Immune metabolic restoration in systemic lupus erythematosus: the impact of gut microbiota, probiotics, and nutritional synergy

in Immunological Tolerance and Regulation

Douae Nihed Habiballah
Fanzhu Li
Lai Jiang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602235

6,097 views
6 citations

Editorial

Published on 20 May 2025

Editorial: The liver’s dilemma: sensing real danger in a sea of PAMPs

in Immunological Tolerance and Regulation

Ian N. Crispe
Andrea Henriques Pons

Frontiers in Immunology

doi 10.3389/fimmu.2025.1591911

1,138 views

Review

Published on 16 May 2025

Recent advances in regulatory immune cells: exploring the world beyond Tregs

in Immunological Tolerance and Regulation

Peng Shi
Yi Yu
Hongwei Xie
Xiaofang Yin
Xue Chen
Yongfei Zhao
Hai Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1530301

6,861 views
7 citations

Original Research

Published on 16 May 2025

Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology

in Immunological Tolerance and Regulation

Xinyao Zhou
Wuqian Wang
Luan Chen
Yingjun Yang
Xing Wei
Jia Zhou
Kuan Sun
Ping Tang
Xiaofang Sun
Shengying Qin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1542034

4,055 views
1 citation

Review

Published on 15 May 2025

Migrasomes: key players in immune regulation and promising medical applications

in Immunological Tolerance and Regulation

Shuping Li
Yanjie Zhou
Tingting Hu
Mei Li
Yao Luo
Jie Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1592314

3,773 views
3 citations

Review

Published on 14 May 2025

Bronchial anastomotic complications as a microvascular disruption in a mouse model of airway transplantation

in Immunological Tolerance and Regulation

Mohammad Afzal Khan
Subarna Bhusal
Christine L. Lau
Alexander Sasha Krupnick

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567657

3,186 views
2 citations

Original Research

Published on 14 May 2025

Th2 predominance and decreased NK cells in patients with hereditary angioedema

in Immunological Tolerance and Regulation

Linda Sundler Björkman
Evelina Elmér
Arne Egesten
Lillemor Skattum

Frontiers in Immunology

doi 10.3389/fimmu.2025.1536128

2,557 views
2 citations

Mini Review

Published on 12 May 2025

Regulation of the immune microenvironment and immunotherapy after liver transplantation

in Immunological Tolerance and Regulation

Tianyi Lan
Gang Wu
Bangyou Zuo
Jingming Yang
Pan He
Yu Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1602877

2,705 views
4 citations

Original Research

Published on 12 May 2025

EV-microRNA signatures in pregnant women with idiopathic recurrent pregnancy loss: deciphering microRNAome pathway networks at feto-maternal interface

in Immunological Tolerance and Regulation

Chitra Bhardwaj
Minakshi Rohilla
Seema Chopra
Anupriya Kaur
Inusha Panigrahi
Priyanka Srivastava

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578738

4,351 views
1 citation

1,665 articles

articles

‘Immune reset plus’: the case for combining immunotherapies to maintain self-tolerance in autoimmune diseases

Anti-IgE therapy versus allergen-specific immunotherapy for food allergy: weighing the pros and cons

Macrophages in chronic infections: regulation and remodeling

Decidual macrophage subsets and polarization puzzle during the human early pregnancy

Interferon Regulatory Factor 4 dose-dependently controls peripheral Treg cell differentiation and homeostasis by modulating chromatin accessibility in mice

Platelets in infection: intrinsic roles and functional outcomes

LYN and CYBB are pivotal immune and inflammatory genes as diagnostic biomarkers in recurrent spontaneous abortion

Editorial: Community series in autoantibodies, volume II

Correction: Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology

Tumor necrosis factor receptor 2 in allergen tolerance: a perspective view

IL-24 producing regulatory T and B lymphocytes in endometriosis

Differential metabolic pathways underlie THC- and CBD-mediated inhibition of B-cell activation in both young and aged mice

Expression and correlation of SOCS3 and Eotaxin mRNA and proteins levels in nasal mucosal tissue of allergic rhinitis patients

Editorial: Host-pathogen interactions during pregnancy: mechanisms of maternal and fetal immunity

Insights into regulatory T-cell and type-I interferon roles in determining abacavir-induced hypersensitivity or immune tolerance

Immune metabolic restoration in systemic lupus erythematosus: the impact of gut microbiota, probiotics, and nutritional synergy

Editorial: The liver’s dilemma: sensing real danger in a sea of PAMPs

Recent advances in regulatory immune cells: exploring the world beyond Tregs

Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology

Migrasomes: key players in immune regulation and promising medical applications

Bronchial anastomotic complications as a microvascular disruption in a mouse model of airway transplantation

Th2 predominance and decreased NK cells in patients with hereditary angioedema

Regulation of the immune microenvironment and immunotherapy after liver transplantation

EV-microRNA signatures in pregnant women with idiopathic recurrent pregnancy loss: deciphering microRNAome pathway networks at feto-maternal interface