Frontiers in Immunology

Original Research

Published on 29 Aug 2025

Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic nephropathy

in Inflammation

Junming Huang
Dong Pang
Chenglong Fan
Guanglin Yang
Jinji Chen
Shaohua Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627173

4,819 views
3 citations

Review

Published on 29 Aug 2025

Neuroinflammation is responsible for pain in endometriosis - targeting the JAK-STAT pathway and mast cell activation

in Inflammation

Monika Golinska
Maria Wołyniak
Piotr Kulesza
Wojciech Fendler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1621178

5,435 views

Mini Review

Published on 29 Aug 2025

Mechanisms and therapeutic strategies of macrophages and neutrophils inducing ulcerative colitis progression

in Inflammation

Haogeng Wang
Taixi Huang
Yuxia Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1615340

5,376 views
2 citations

Original Research

Published on 29 Aug 2025

Development of a novel prognostic score for 1-year survival in immunotherapy-treated patients with unresectable HCC: the ALIVE-IO score

in Inflammation

Spyridon Pantzios
Orestis Sidiropoulos
Antonia Syriha
Nikolaos Ptohis
Ioannis Skouras
Evgenia Mainta
Dimitris P. Korkolis
Nikolaos Machairas
Georgios C. Sotiropoulos
Ioannis Elefsiniotis

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648248

1,907 views

Original Research

Published on 28 Aug 2025

ATP/P2X7 receptor signal aggravates ischemic stroke injury by activating Th17 cells via STAT3/IL-21 pathway

in Inflammation

Wenying Liu
Denghui Li
Mengjie Zhang
Jun Yin
Peng Wang
Paiyu Liu
Zhiqiang Song
Bing Ni
Yanmeng Peng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558307

5,321 views
1 citation

Review

Published on 28 Aug 2025

S100 proteins as a key immunoregulatory mechanism for NLRP3 inflammasome

in Inflammation

Shahinur Acter
Qing Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663547

3,709 views
4 citations

Review

Published on 28 Aug 2025

The alarmin tandem: unraveling the complex effect of S100A8/A9 – from atherosclerosis to cardiac arrhythmias

in Inflammation

Dan-Alexandru Cozac
Vasile-Bogdan Halațiu
Alina Scridon

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630410

3,592 views
6 citations

Original Research

Published on 28 Aug 2025

Multi-omics approach to personalised treatment: insights into thrombus-derived exosome regulation in cardiomyocyte ferritinophagy

in Inflammation

Youfu He
Liqiong Ai
Yu Zhou
Jing Huang
Xiangshu Long
Qiang Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607355

4,060 views
4 citations

Mini Review

Published on 28 Aug 2025

Hsp90 as a pathophysiological factor and emerging therapeutic target in atopic dermatitis

in Inflammation

Stefan Tukaj

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658399

5,346 views

Original Research

Published on 27 Aug 2025

Hydrogen sulfide as a therapeutic agent for diabetic wounds: effects on inflammation and fibroblast pyroptosis

in Inflammation

Fusheng Zhao
Yuanyuan Li
Qunying Hu
Jiali Xu
Na Zhang
Yonglan Chen
Xinyue Jiang
Chunfu Gu
Kexin Zhang
Geng Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1558443

2,978 views
3 citations

Mini Review

Published on 27 Aug 2025

Endothelial activation in thromboangiitis obliterans: mechanisms and therapeutic horizons

in Inflammation

Wanting Wang
Siyao Chang
Gang Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668203

2,687 views
1 citation

Original Research

Published on 27 Aug 2025

Study on the molecular mechanism of matrine in improving rheumatoid arthritis by targeting the NAV2-Wnt3a/β-catenin axis to coordinately regulate the inflammatory-osteolytic loop

in Inflammation

Qianyu Guo
Meie Liang
Zhen Li
Jie Li
Ke Xu
Liyun Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646918

2,693 views
1 citation

Brief Research Report

Published on 27 Aug 2025

E-cigarette vapor amplifies neutrophilic inflammation and proteolytic EVs in response to LPS

in Inflammation

Lawrence W. Rasmussen
Dakota C. Finley
Julian B. Smith
Aaron S. Noa
J. Edwin Blalock
Amit Gaggar
Matthew C. Madison

Frontiers in Immunology

doi 10.3389/fimmu.2025.1665936

2,483 views
1 citation

Original Research

Published on 27 Aug 2025

A genetically determined molecular switch modulates the anti-inflammatory potential of human IgA

in Inflammation

Andrew W. Gibson
Jianming Wu
R. Curtis Hendrickson
Travis Ptacek
James Mobley
Jeffrey C. Edberg
Robert P. Kimberly

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641351

1,710 views

Review

Published on 26 Aug 2025

New insights into mesenchymal stem cells in inflammatory subtypes of asthma

in Inflammation

Zheng-yan Hou
Yu-qiu Hao
Lin Zhang
Wei Li
Peng Gao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649597

4,032 views

Original Research

Published on 26 Aug 2025

MicroRNA-132 regulates quinolinic acid production in the brain during LPS-induced neuroinflammation

in Inflammation

Amir Mohamed Kezai
Papa Yaya Badiane
Benjamin Hennart
Delphine Allorge
Sabrina Marion
Sébastien S. Hébert

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644783

2,721 views

Clinical Trial

Published on 26 Aug 2025

The endoplasmic reticulum stress status of CD4+ T lymphocytes and its association with mTOR-mediated autophagic-lysosomal disorder in elderly sepsis patients

in Inflammation

Wei Cheng
Jiahui Zhang
Dongkai Li
Yawen Xie
Xianli Lei
Hao Wang
Na Cui

Frontiers in Immunology

doi 10.3389/fimmu.2025.1648075

1,809 views

Review

Published on 26 Aug 2025

Regulatory effect of inflammatory mediators in spinal cord injury

in Inflammation

Wen-cong Zeng
Fang-jun Zeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1619337

3,231 views
3 citations

Original Research

Published on 26 Aug 2025

Regulation of ZFP36 by lncOlfr29 promotes inflammation through NLRP3

in Inflammation

Wenyue Cheng
Fan Li
Yuan Zhang
Yunhuan Gao
Rongcun Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1642783

2,101 views

Correction

Published on 25 Aug 2025

Correction: Shared diagnostic genes and potential mechanism between PCOS and recurrent implantation failure revealed by integrated transcriptomic analysis and machine learning

in Inflammation

Wenhui Chen
Qingling Yang
Linli Hu
Mengchen Wang
Ziyao Yang
Xinxin Zeng
Yingpu Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682282

1,378 views

Review

Published on 22 Aug 2025

The role of reactive oxygen species in the transformation from prostatitis to prostate cancer: a review

in Inflammation

Kaihua Tang
Zhipeng Jiang
Wen Luo
Jing Li
DeCan Liang
Lei Liu
ZongMin Long

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662792

3,128 views
1 citation

Mini Review

Published on 22 Aug 2025

Microglial pyroptosis as a therapeutic target after traumatic spinal cord injury: current progress and future directions

in Inflammation

Lei Shi
Qiheng Qian
Jiding Xie
Taoshuo Yang
Xinyu Zhao
Xiangqi Meng
Jingang Dai
Qiguan Jin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1649790

4,199 views
2 citations

Review

Published on 21 Aug 2025

Death-associated protein kinase 1: a double-edged sword in health and disease

in Inflammation

Xiuli Zhang
Yehuda G. Assaraf
Yao Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593394

3,662 views
1 citation

Original Research

Published on 21 Aug 2025

Low-dose extracorporeal shock wave attenuates sepsis-related acute lung injury by targeting mitochondrial dysfunction and pyroptosis crosstalk in type II alveolar epithelial cells

in Inflammation

Jianning Guo
Xiaoxuan Qu
Ruidong Ge
Die Liu
Jing Liu
Qin Hui
Fang Ye
Yuanmei Chen
Chao Wang
Di Lv

Frontiers in Immunology

doi 10.3389/fimmu.2025.1637378

4,513 views

5,790 articles

articles

Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic nephropathy

Neuroinflammation is responsible for pain in endometriosis - targeting the JAK-STAT pathway and mast cell activation

Mechanisms and therapeutic strategies of macrophages and neutrophils inducing ulcerative colitis progression

Development of a novel prognostic score for 1-year survival in immunotherapy-treated patients with unresectable HCC: the ALIVE-IO score

ATP/P2X7 receptor signal aggravates ischemic stroke injury by activating Th17 cells via STAT3/IL-21 pathway

S100 proteins as a key immunoregulatory mechanism for NLRP3 inflammasome

The alarmin tandem: unraveling the complex effect of S100A8/A9 – from atherosclerosis to cardiac arrhythmias

Multi-omics approach to personalised treatment: insights into thrombus-derived exosome regulation in cardiomyocyte ferritinophagy

Hsp90 as a pathophysiological factor and emerging therapeutic target in atopic dermatitis

Hydrogen sulfide as a therapeutic agent for diabetic wounds: effects on inflammation and fibroblast pyroptosis

Endothelial activation in thromboangiitis obliterans: mechanisms and therapeutic horizons

Study on the molecular mechanism of matrine in improving rheumatoid arthritis by targeting the NAV2-Wnt3a/β-catenin axis to coordinately regulate the inflammatory-osteolytic loop

E-cigarette vapor amplifies neutrophilic inflammation and proteolytic EVs in response to LPS

A genetically determined molecular switch modulates the anti-inflammatory potential of human IgA

New insights into mesenchymal stem cells in inflammatory subtypes of asthma

MicroRNA-132 regulates quinolinic acid production in the brain during LPS-induced neuroinflammation

The endoplasmic reticulum stress status of CD4+ T lymphocytes and its association with mTOR-mediated autophagic-lysosomal disorder in elderly sepsis patients

Regulatory effect of inflammatory mediators in spinal cord injury

Regulation of ZFP36 by lncOlfr29 promotes inflammation through NLRP3

Correction: Shared diagnostic genes and potential mechanism between PCOS and recurrent implantation failure revealed by integrated transcriptomic analysis and machine learning

The role of reactive oxygen species in the transformation from prostatitis to prostate cancer: a review

Microglial pyroptosis as a therapeutic target after traumatic spinal cord injury: current progress and future directions

Death-associated protein kinase 1: a double-edged sword in health and disease

Low-dose extracorporeal shock wave attenuates sepsis-related acute lung injury by targeting mitochondrial dysfunction and pyroptosis crosstalk in type II alveolar epithelial cells