Frontiers in Immunology | Mucosal Immunity

Original Research

Published on 22 Oct 2025

Humoral immune activation within tertiary lymphoid structures is correlated with poor outcomes in oral lichen planus and lichenoid lesions

in Mucosal Immunity

Xiaojie Yang
Annan Dai
Yirao Lai
Lei Pan
Yiwen Deng
Xuemin Shen
Xiaozhe Han
Lei Sun
Yufeng Wang
Guoyao Tang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667976

1,999 views

Original Research

Published on 21 Oct 2025

Discovery of protease inhibitors from bacteria as novel adjuvants for oral vaccine formulations

in Mucosal Immunity

Lorena M. Coria
Celeste Pueblas Castro
Laura Bruno
Helder I. Nakaya
Karina A. Pasquevich
Juliana Cassataro

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679540

2,364 views
1 citation

Review

Published on 14 Oct 2025

Salivary gland macrophages in health and disease: heterogeneity, niche crosstalk, and therapeutic avenues

in Mucosal Immunity

Xinglei Li
Yan Feng
Huixin Xue
Xinxin Ni

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688738

5,191 views

Original Research

Published on 13 Oct 2025

The chemokines CCL22 and CCL17 are a defining feature of type 2 stimulated human lung macrophages and exhibit different metabolic dependencies

in Mucosal Immunity

Amanda J. L. Ridley
Annabel J. Curle
Stefano A. P. Colombo
Joshua J. Hughes
Douglas P. Dyer
Angela Simpson
Lee M. Booty
Maria Feeney
Peter C. Cook
Andrew S. MacDonald

Frontiers in Immunology

doi 10.3389/fimmu.2025.1654717

3,004 views

Original Research

Published on 10 Oct 2025

Elevated SerpinB2 regulates MUC5AC expression via STAT6 signaling in nasal epithelial cells in allergic rhinitis

in Mucosal Immunity

Jing Li
Qianbo Cui
Zhipeng Li
Ying Zhu
Jing Wang
Wei Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1669777

2,482 views

Original Research

Published on 03 Oct 2025

Annexin A1 levels affect microbiota in health and DSS-induced colitis/inflammatory bowel disease development

in Mucosal Immunity

Luana Filippi Xavier
Ranko Gacesa
Gustavo Henrique Oliveira da Rocha
Milena Fronza Broering
Pablo Scharf
Fabiana da Silva Lima
Klaas Nico Faber
Hermie Harmsen
Christian Hoffmann
Sandra Helena Poliselli Farsky

Frontiers in Immunology

doi 10.3389/fimmu.2025.1679071

3,952 views
2 citations

Original Research

Published on 02 Oct 2025

Transepidermal water loss increases during murine food anaphylaxis and reflects reaction severity

in Mucosal Immunity

Benjamin N. Woerner
Joseph Abbo
Allison Wang
Melanie K. Donahue
Judy Hines
Jessica O’Konek
Simon P. Hogan
James R. Baker
Charles F. Schuler

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667569

1,903 views

Editorial

Published on 30 Sep 2025

Editorial: Advances in understanding mucosal immunity in coronaviruses: from mechanisms to vaccines

in Mucosal Immunity

Farhat Afrin
Qibo Zhang
Wael Alturaiki
Waleed Mahallawi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1702286

2,032 views

Editorial

Published on 29 Sep 2025

Editorial: Natural products and intestinal mucosal immunity

in Mucosal Immunity

Haiqiang Yao
Shanlan Mo
Pinpin Sui
Chunping Wan
Jin-Yi Wan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1682978

2,372 views

Review

Published on 25 Sep 2025

The microbiota-gut-brain axis in depression: unraveling the relationships and therapeutic opportunities

in Mucosal Immunity

Zhangcheng Zhu
Yiwen Cheng
Xia Liu
Xiaocui Xu
Wenwen Ding
Zongxin Ling
Jiaming Liu
Guangyong Cai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1644160

10,545 views
9 citations

Original Research

Published on 25 Sep 2025

Piezo1 protects against inflammatory bone loss via a unique Ca2+-independent mechanism in osteoclasts

in Mucosal Immunity

Satoru Shindo
Shin Nakamura
Avery Hawthorne
Alireza Heidari
Maria Rita Pastore
Motoki Okamoto
Maiko Suzuki
Manuel Salinas
Takumi Memida
Dmitriy Minond

Frontiers in Immunology

doi 10.3389/fimmu.2025.1661538

6,023 views
3 citations

Original Research

Published on 23 Sep 2025

Peripheral monocytes from Crohn’s disease patients retain functional responsiveness to GM-CSF during active disease

in Mucosal Immunity

Paul P. Winkel
Wendy Bergmann-Ewert
Johannes Reiner
Astrid Huth
Dana Kleimeier
Rosaely Casalegno Garduño
Ida M. Wrobel
Grazyna Domanska
Jan Däbritz
Elisa Wirthgen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1663713

4,114 views

Review

Published on 19 Sep 2025

The role of dysbiosis in shaping host immunity in endometrial cancer development

in Mucosal Immunity

Wiktoria Wierzbińska
Olga Kuźmycz
Aleksandra Kowalczyk
Paweł Stączek

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627285

2,701 views
1 citation

Review

Published on 18 Sep 2025

Gut microbiota: a promising new target in immune tolerance

in Mucosal Immunity

Nourah Almansour
Fatema Al-Rashed
Khubaib Choudhry
Hend Alqaderi
Sardar Sindhu
Fahd Al-Mulla
Rasheed Ahmad

Frontiers in Immunology

doi 10.3389/fimmu.2025.1607388

6,915 views
4 citations

Original Research

Published on 17 Sep 2025

Electroacupuncture restores intestinal mucosal barrier in IBS-D rats by modulating mast cell-derived exosomal MiR-149-5p

in Mucosal Immunity

Yujun Hou
Fangli Luo
Kai Wang
Ying Chen
Lu Wang
Yanqiu Li
Siqi Wang
Junpeng Yao
Ying Li
Siyuan Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1641484

4,597 views
1 citation

Review

Published on 16 Sep 2025

Leveraging the role of the microbiome in endometriosis: novel non-invasive and therapeutic approaches

in Mucosal Immunity

Eleni Andria Kalopedis
Amine Zorgani
Dmitry A. Zinovkin
Muruj Barri
C. David Wood
Md Zahidul I. Pranjol

Frontiers in Immunology

doi 10.3389/fimmu.2025.1631522

6,965 views
3 citations

Review

Published on 15 Sep 2025

TNFSF14 (LIGHT) in intestinal inflammation: balancing immune activation and resolution in IBD

in Mucosal Immunity

Rabia S. Mousa
Pietro Invernizzi
Joanne L. Jones
Hani S. Mousa

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657071

4,050 views
1 citation

Case Report

Published on 12 Sep 2025

Case Report: Relapsing pleural effusions and coated aorta revealing Erdheim–Chester disease

in Mucosal Immunity

Tiépé Rokia Ouattara
Théo Pezel
Gwenael Lorillon
Aïcha Kante
Peggy Reiner
Aurélie Le Gal
Marine Lefèvre
Thibault Vieira
Stéphane Mouly
Abdellatif Tazi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585541

1,929 views

Review

Published on 12 Sep 2025

The AhR/IL-22 axis in chronic gut inflammation: unraveling mechanisms and therapeutic prospects

in Mucosal Immunity

Huimin Kang
Zheng Chen
Baodong Wang
Zhiyun Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668173

5,534 views
7 citations

Editorial

Published on 05 Sep 2025

Editorial: Mucosal immunity after vaccination

in Mucosal Immunity

Mohd Arish
Mireia López-Siles
Farha Naz

Frontiers in Immunology

doi 10.3389/fimmu.2025.1690399

3,102 views

Review

Published on 03 Sep 2025

Immuno-epigenetic paradigms in coronavirus infection

in Mucosal Immunity

Swati Gupta
Hassan A. Hemeg
Farhat Afrin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596135

7,071 views
1 citation

Original Research

Published on 03 Sep 2025

Penicillamine ameliorates intestinal barrier damage in dextran sulfate sodium-induced experimental colitis mice by inhibiting cuproptosis

in Mucosal Immunity

Jiaze Ma
Yimeng Ma
Shuangshuang Wang
Wenwen Tang
Chen Chen
Yang Li
Yugen Chen
Tuo Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1580963

3,439 views
1 citation

Original Research

Published on 29 Aug 2025

Molecular mechanisms of ferroptosis in ulcerative colitis: insights from machine learning, WGCNA, and immune cell infiltration analysis

in Mucosal Immunity

Leilei Zhai
Huiyue Pan
Ziyi Guo
Wei Zhou
Qi Ding
Haikun Wang
Qian Chen
Ping Yao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1615186

8,523 views

Systematic Review

Published on 28 Aug 2025

Temporal dynamics of early inflammatory markers after professional dental cleaning: a meta-analysis and spline-based meta-regression of TNF-α, IL-1β, IL-6, and (hs)CRP

in Mucosal Immunity

Martina Cardisciani
Sara Di Nicolantonio
Serena Altamura
Eleonora Ortu
Rita Del Pinto
Davide Pietropaoli

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634622

4,367 views
4 citations

1,024 articles

articles

Humoral immune activation within tertiary lymphoid structures is correlated with poor outcomes in oral lichen planus and lichenoid lesions

Discovery of protease inhibitors from bacteria as novel adjuvants for oral vaccine formulations

Salivary gland macrophages in health and disease: heterogeneity, niche crosstalk, and therapeutic avenues

The chemokines CCL22 and CCL17 are a defining feature of type 2 stimulated human lung macrophages and exhibit different metabolic dependencies

Elevated SerpinB2 regulates MUC5AC expression via STAT6 signaling in nasal epithelial cells in allergic rhinitis

Annexin A1 levels affect microbiota in health and DSS-induced colitis/inflammatory bowel disease development

Transepidermal water loss increases during murine food anaphylaxis and reflects reaction severity

Editorial: Advances in understanding mucosal immunity in coronaviruses: from mechanisms to vaccines

Editorial: Natural products and intestinal mucosal immunity

The microbiota-gut-brain axis in depression: unraveling the relationships and therapeutic opportunities

Piezo1 protects against inflammatory bone loss via a unique Ca2+-independent mechanism in osteoclasts

Peripheral monocytes from Crohn’s disease patients retain functional responsiveness to GM-CSF during active disease

The role of dysbiosis in shaping host immunity in endometrial cancer development

Gut microbiota: a promising new target in immune tolerance

Electroacupuncture restores intestinal mucosal barrier in IBS-D rats by modulating mast cell-derived exosomal MiR-149-5p

Leveraging the role of the microbiome in endometriosis: novel non-invasive and therapeutic approaches

TNFSF14 (LIGHT) in intestinal inflammation: balancing immune activation and resolution in IBD

Case Report: Relapsing pleural effusions and coated aorta revealing Erdheim–Chester disease

The AhR/IL-22 axis in chronic gut inflammation: unraveling mechanisms and therapeutic prospects

Editorial: Mucosal immunity after vaccination

Immuno-epigenetic paradigms in coronavirus infection

Penicillamine ameliorates intestinal barrier damage in dextran sulfate sodium-induced experimental colitis mice by inhibiting cuproptosis

Molecular mechanisms of ferroptosis in ulcerative colitis: insights from machine learning, WGCNA, and immune cell infiltration analysis

Temporal dynamics of early inflammatory markers after professional dental cleaning: a meta-analysis and spline-based meta-regression of TNF-α, IL-1β, IL-6, and (hs)CRP