Frontiers in Immunology | Viral Immunology

Original Research

Published on 22 May 2025

Multiomics analysis unveils key biomarkers during dynamic progress of IAV infection in mice

in Viral Immunology

Huan Lei
Yixi Xu
Hao Zhang
Bin Zhang
Wenjun Luo
Xiao Liu
Haijun Zhang
Jinming Yang
Wen Wen
Ping Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1566690

4,012 views
4 citations

Original Research

Published on 21 May 2025

Predominant T-cell epitopes of SARS-CoV-2 restricted by multiple prevalent HLA-B and HLA-C allotypes in Northeast Asia

in Viral Immunology

Yu Zhao
Min Peng
Chengtao He
Min Li
Xuelian Han
Qiang Fu
Yandan Wu
Fangping Yue
Chunguang Yan
Guangyu Zhao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1545510

2,247 views
1 citation

Original Research

Published on 21 May 2025

Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV

in Viral Immunology

Sarah J. Byrnes
Janna Jamal Eddine
Jingling Zhou
Emily Chalmers
Emma Wanicek
Narin Osman
Trisha A. Jenkins
Michael Roche
Bruce J. Brew
Jacob D. Estes

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570692

4,144 views
4 citations

Original Research

Published on 20 May 2025

Distribution and potential involvement of PTEN in the innate immune response during viral infections in Cherry Valley ducks

in Viral Immunology

Wende Chen
Shaojie Han
Rong Li
Shuo Li
Zhi Cao
Qing Pan
Gen Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1570872

1,971 views
1 citation

Original Research

Published on 20 May 2025

SIV/SARS-CoV-2 coinfection in rhesus macaques impacts viral shedding, host immunity, the microbiome, and viral evolution

in Viral Immunology

Megan N. Fredericks
Zohar Kolodner
Adam Waalkes
Kaitlin Sawatzki
Linhui Hao
Dustin R. Long
Kelsi Penewit
Cecily C. Midkiff
Carter J. McCormick
Semira Beraki

Frontiers in Immunology

doi 10.3389/fimmu.2025.1587688

3,795 views
1 citation

Review

Published on 16 May 2025

Metabolic reprogramming in viral infections: the interplay of glucose metabolism and immune responses

in Viral Immunology

Mahmoud Darweesh
Saeed Mohammadi
Mina Rahmati
Moosa Al-Hamadani
Ahmed Al-Harrasi

Frontiers in Immunology

doi 10.3389/fimmu.2025.1578202

7,167 views
16 citations

Original Research

Published on 16 May 2025

Correlation between severe acute respiratory syndrome coronavirus 2 infection and serum anti-neutrophil cytoplasmic antibody formation

in Viral Immunology

Hao Huang
Yu-Jie Zang
Zheng-Guo Li
Qian Li
Chun-Yan Ma
Hai-Yuan Zhao
Hang Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1593577

2,239 views
1 citation

Original Research

Published on 16 May 2025

The protein interaction of mitochondrial transcription factors A and B2 is associated with 30-day survival in critical COVID-19

in Viral Immunology

Britta Westhus
Patrick Thon
Lars Palmowski
Katharina Rump
Björn Koos
Frederik Wiebel
Birte Dyck
Martin Eisenacher
Barbara Sitek
Stephanie Pfaender

Frontiers in Immunology

doi 10.3389/fimmu.2025.1445403

2,322 views

Mini Review

Published on 16 May 2025

Estrogen and viral infection

in Viral Immunology

Xiangrui Wei
Longyan Hong
Hao Liang
Ke Ren
Wenqing Man
Yinghui Zhao
Pengbo Guo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1556728

4,893 views
3 citations

Original Research

Published on 16 May 2025

Comparison of four different assays to evaluate cellular-mediated immunity against cytomegalovirus in solid organ transplantation

in Viral Immunology

Angela Casas-Parra
Hendrik Veltman
Alba Romero-Caballero
Rosana Gelpi-Remiro
Marc Boigues-Pons
Imán Allalou
Ian Linares-Pardo
Anna Vila-Santandreu
Eva Martínez-Cáceres
María Iglesias-Escudero

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567253

3,350 views

Original Research

Published on 14 May 2025

Type III interferon, age and IFNL gene single nucleotide polymorphisms determine the characteristics of H1N1 influenza infection

in Viral Immunology

Wenbo Zhu
Shao Wang
Chenchen Guan
Shuangquan Liu
Hongbo Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1592841

2,816 views
4 citations

Mini Review

Published on 14 May 2025

The intestinal interferon system and specialized enterocytes as putative drivers of HIV latency

in Viral Immunology

Rachel L. Creighton
Sean M. Hughes
Florian Hladik
Germán G. Gornalusse

Frontiers in Immunology

doi 10.3389/fimmu.2025.1589752

3,424 views

Original Research

Published on 12 May 2025

HDL-C as a novel predictor of immune reconstitution in people living with HIV: insights from a baseline-to-dynamic change cohort study in China, 2005–2022

in Viral Immunology

Xiaorui Li
Liqin Sun
Yun He
Fang Zhao
Yinsong Luo
Chenye Liu
Yiyao Hu
Yuxin Jiang
Hongzhou Lu
Jiaye Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1520615

2,463 views
1 citation

Original Research

Published on 12 May 2025

Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase

in Viral Immunology

Yukari Nishikawa
Kosuke Yamaguchi
Ma’arif Athok Shofiudin
Momone Mimura
Miyako Takata
Shu Mihara
Takeru Kawakami
Ayumu Doi
Risa Matsuda
Hiroyuki Kato

Frontiers in Immunology

doi 10.3389/fimmu.2025.1594296

3,821 views
3 citations

Review

Published on 12 May 2025

Underestimated virus impaired cognition-more evidence and more work to do

in Viral Immunology

Maher Un Nisa Awan
Faisal Mahmood
Xiao-bin Peng
Fenshuang Zheng
Jun Xu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1550179

2,992 views
1 citation

Original Research

Published on 09 May 2025

Virus-specific host responses and gene signatures following infection with major SARS-CoV-2 variants of concern: role of ZBP1 in viral clearance and lung inflammation

in Viral Immunology

Amany Elsharkawy
Hamid Reza Jahantigh
Anchala Guglani
Shannon Stone
Komal Arora
Mukesh Kumar

Frontiers in Immunology

doi 10.3389/fimmu.2025.1557535

5,628 views
7 citations

Original Research

Published on 09 May 2025

Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice

in Viral Immunology

Yu-Syuan You
Wan-Ting Chang
Chia-Lang Hsu
Hui-Ying Wang
Yan-Fong Lu
InKyeom Kim
Shiang-Jong Tzeng

Frontiers in Immunology

doi 10.3389/fimmu.2025.1548814

3,189 views

Original Research

Published on 09 May 2025

Simultaneously ultrasensitive and differential detection of SARS-CoV-2, adenovirus and influenza a virus using multiplex fluorescence lateral flow immunoassay

in Viral Immunology

Xiaoyan Li
Changxu Zhao
Guangzheng Hou
Zhihua Sun
Xiaomei Liu
Yanlei Ding
Yi Fang
Qiqi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1540676

3,628 views
5 citations

Review

Published on 09 May 2025

Interferon and immunity: the role of microRNA in viral evasion strategies

in Viral Immunology

Mobina Bayat
Rahil Nahid-Samiei
Javid Sadri Nahand
Behrouz Naghili

Frontiers in Immunology

doi 10.3389/fimmu.2025.1567459

3,804 views
6 citations

Original Research

Published on 09 May 2025

Reduced immune response to SARS-CoV-2 infection in the elderly after 6 months

in Viral Immunology

Qin Luo
Qinqin Song
Yan Li
Kexin Zong
Ti Liu
Junming He
Guoyong Mei
Haijun Du
Zhiqiang Xia
Mi Liu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596065

4,112 views
2 citations

Original Research

Published on 09 May 2025

Coagulation functions and factors correlated with central nervous system infection in herpes zoster patients

in Viral Immunology

Yanrong Yuan
Jing Gu
Huili Liu
Yu Wang
Zeyu Sun
Dongli Pan
Yongxing Yan

Frontiers in Immunology

doi 10.3389/fimmu.2025.1511901

2,118 views

Original Research

Published on 09 May 2025

The subsets of blood circulating T-cells associated with the development and prognosis of coinfection in patients with critical COVID-19

in Viral Immunology

Xingming Li
Hongqiong Peng
Yunchuan Wang
Shiying He
Xueting Yang
Jiayue Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1586302

1,552 views

Original Research

Published on 08 May 2025

Development of a potent neutralizing nanobody against canine distemper virus hemagglutinin protein

in Viral Immunology

Lirong Xiao
Zhuqing Wu
Jingliang Su
Qingmin Wu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1585793

3,882 views
1 citation

Review

Published on 08 May 2025

Puumala orthohantavirus: prevalence, biology, disease, animal models and recent advances in therapeutics development and structural biology

in Viral Immunology

Alina Tscherne
Pablo Guardado-Calvo
Jordan J. Clark
Robert Krause
Florian Krammer

Frontiers in Immunology

doi 10.3389/fimmu.2025.1575112

6,765 views
4 citations

2,757 articles

articles

Multiomics analysis unveils key biomarkers during dynamic progress of IAV infection in mice

Predominant T-cell epitopes of SARS-CoV-2 restricted by multiple prevalent HLA-B and HLA-C allotypes in Northeast Asia

Neuroinflammation associated with proviral DNA persists in the brain of virally suppressed people with HIV

Distribution and potential involvement of PTEN in the innate immune response during viral infections in Cherry Valley ducks

SIV/SARS-CoV-2 coinfection in rhesus macaques impacts viral shedding, host immunity, the microbiome, and viral evolution

Metabolic reprogramming in viral infections: the interplay of glucose metabolism and immune responses

Correlation between severe acute respiratory syndrome coronavirus 2 infection and serum anti-neutrophil cytoplasmic antibody formation

The protein interaction of mitochondrial transcription factors A and B2 is associated with 30-day survival in critical COVID-19

Estrogen and viral infection

Comparison of four different assays to evaluate cellular-mediated immunity against cytomegalovirus in solid organ transplantation

Type III interferon, age and IFNL gene single nucleotide polymorphisms determine the characteristics of H1N1 influenza infection

The intestinal interferon system and specialized enterocytes as putative drivers of HIV latency

HDL-C as a novel predictor of immune reconstitution in people living with HIV: insights from a baseline-to-dynamic change cohort study in China, 2005–2022

Distinct immunity dynamics of natural killer cells in mild and moderate COVID-19 cases during the Omicron variant phase

Underestimated virus impaired cognition-more evidence and more work to do

Virus-specific host responses and gene signatures following infection with major SARS-CoV-2 variants of concern: role of ZBP1 in viral clearance and lung inflammation

Wip1 inhibitor CCT007093 alleviates immune exhaustion of lymphocytes via p65 NF-κB and YY1 in chronic hepatitis B virus infection in mice

Simultaneously ultrasensitive and differential detection of SARS-CoV-2, adenovirus and influenza a virus using multiplex fluorescence lateral flow immunoassay

Interferon and immunity: the role of microRNA in viral evasion strategies

Reduced immune response to SARS-CoV-2 infection in the elderly after 6 months

Coagulation functions and factors correlated with central nervous system infection in herpes zoster patients

The subsets of blood circulating T-cells associated with the development and prognosis of coinfection in patients with critical COVID-19

Development of a potent neutralizing nanobody against canine distemper virus hemagglutinin protein

Puumala orthohantavirus: prevalence, biology, disease, animal models and recent advances in therapeutics development and structural biology