Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 15 Jan 2025

Predicting patient outcomes with gene-expression biomarkers from colorectal cancer organoids and cell lines

in Molecular Diagnostics and Therapeutics

Alexandra Razumovskaya
Mariia Silkina
Andrey Poloznikov
Timur Kulagin
Maria Raigorodskaya
Nina Gorban
Anna Kudryavtseva
Maria Fedorova
Boris Alekseev
Alexander Tonevitsky

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1531175

1,820 views

Original Research

Published on 09 Jan 2025

Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis

in Molecular Diagnostics and Therapeutics

Yan Zhang
Xiujuan Chen
Yuan Lin
Xiaoqing Liu
Xiumei Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504015

1,478 views

Mini Review

Published on 08 Jan 2025

Artificial molecular motors in biological applications

in Molecular Diagnostics and Therapeutics

Fuli Fan
Songshen Liu
Yuting Yan
Peng Zhang
Kui Che

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1510619

1,434 views

Editorial

Published on 07 Jan 2025

Editorial: Modelling esophageal adenocarcinoma

in Molecular Diagnostics and Therapeutics

Hisham F. Bahmad
Farah Ballout

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1550595

686 views

Original Research

Published on 07 Jan 2025

Exploring the shared gene signatures and mechanism among three autoimmune diseases by bulk RNA sequencing integrated with single-cell RNA sequencing analysis

in Molecular Diagnostics and Therapeutics

Xiaofang Liu
Bin Li
Yuxi Lin
Xueying Ma
Yingying Liu
Lili Ma
Xiaomeng Ma
Xia Wang
Nanjing Li
Xiaoyun Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1520050

3,450 views

Original Research

Published on 06 Jan 2025

Identification and validation of five ferroptosis-related molecular signatures in keloids based on multiple transcriptome data analysis

in Molecular Diagnostics and Therapeutics

Zhen Sun
Yonghong Qin
Xuanfen Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1490745

1,150 views

Original Research

Published on 06 Jan 2025

Identification and validation of reference genes for quantitative gene expression analysis under 409 and 415 nm antimicrobial blue light treatment

in Molecular Diagnostics and Therapeutics

Beata Kruszewska-Naczk
Mariusz Grinholc
Aleksandra Rapacka-Zdonczyk

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1467726

862 views

Review

Published on 03 Jan 2025

LncRNA HOXA10-AS as a novel biomarker and therapeutic target in human cancers

in Molecular Diagnostics and Therapeutics

Xin Hu
Yong Wang
Sijia Zhang
Xiaosi Gu
Xiaoyu Zhang
Lianlian Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1520498

1,579 views

Original Research

Published on 03 Jan 2025

Unveiling and validating biomarkers related to the IL-10 family in chronic sinusitis with nasal polyps: insights from transcriptomics and single-cell RNA sequencing analysis

in Molecular Diagnostics and Therapeutics

Xinghong Liu
Yi Peng
Ling Guo
Weilan Xiong
Weijiang Liao
Jiangang Fan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1513951

1,285 views

Original Research

Published on 24 Dec 2024

Disparate molecular mechanisms in cardiac ryanodine receptor channelopathies

in Molecular Diagnostics and Therapeutics

Yadan Zhang
Monika Seidel
Camille Rabesahala de Meritens
Astrid Beckmann
Syeda Ahmed
Melanie Hurtz
F. Anthony Lai
Esther Zorio
Dimitris Parthimos
Spyros Zissimopoulos

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1505698

821 views

Original Research

Published on 23 Dec 2024

Prediction of preoperative peritoneal cancer index for pseudomyxoma peritonei by multiple linear regression analysis

in Molecular Diagnostics and Therapeutics

Mingjian Bai
Jing Feng
Jie Liu
Yunxiang Li
Yueming Xu
Fucun Ma
Ruiqing Ma
Guowei Liang
Xuekai Liu
Na Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1512937

748 views

Review

Published on 20 Dec 2024

Effects of Vaccinium-derived antioxidants on human health: the past, present and future

in Molecular Diagnostics and Therapeutics

Amrita Ghosh
Samir C. Debnath
Abir U. Igamberdiev

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1520661

1,035 views

Original Research

Published on 19 Dec 2024

Circulating biomarkers associated with pediatric sickle cell disease

in Molecular Diagnostics and Therapeutics

Cecilia Elorm Lekpor
Felix Abekah Botchway
Adel Driss
Alaijah Bashi
Afua D. Abrahams
Kwadwo Asamoah Kusi
Godfred Futagbi
Ernest Alema-Mensah
William Agbozo
Wesley Solomon

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1481441

1,926 views

Original Research

Published on 19 Dec 2024

Development of 6-amido-4-aminoisoindolyn-1,3-diones as p70S6K1 inhibitors and potential breast cancer therapeutics

in Molecular Diagnostics and Therapeutics

Adrian Thornton
Rajesh Komati
Hogyoung Kim
Jamiah Myers
Kymmia Petty
Rion Sam
Elijah Johnson-Henderson
Keshunna Reese
Linh Tran
Vaniyambadi Sridhar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1481912

930 views

Original Research

Published on 11 Dec 2024

Identification of biomarkers and immune microenvironment associated with pterygium through bioinformatics and machine learning

in Molecular Diagnostics and Therapeutics

Li-Wei Zhang
Ji Yang
Hua-Wei Jiang
Xiu-Qiang Yang
Ya-Nan Chen
Wei-Dang Ying
Ying-Liang Deng
Min-hui Zhang
Hai Liu
Hong-Lei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1524517

1,255 views
1 citation

Original Research

Published on 11 Dec 2024

Integrated multi-omics analysis describes immune profiles in ischemic heart failure and identifies PTN as a novel biomarker

in Molecular Diagnostics and Therapeutics

Ting Xiong
Quhuan Li
Yifan Wang
Ying Kong
Hailin Li
Jie Liu
Yueheng Wu
Fengxia Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1524827

909 views