Frontiers in Neuroscience | Gut-Brain Axis

Original Research

Published on 01 Dec 2025

Alterations in gut microbiota and plasma metabolites: a multi-omics study of mild cognitive impairment in Parkinson’s disease

in Gut-Brain Axis

Zihao Lin
Yangdanyu Li
Yuning Liu
Bo Yang
Peixiao Yin
Chenyang Guan
Yating Fang
Liying Yang
Kun Zan
Guiyun Cui

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1667331

340 views

Original Research

Accepted on 21 Nov 2025

Sulfate Reducing Bacteria Induce -Synuclein in Intestinal and Neuronal cells and tissues and Inhibit Tyrosine Hydroxylase in Neuronal cells

in Gut-Brain Axis

Sudha Singh
Arianne J Capacio
Cody A Braun
Amanda Carroll-Portillo
Sephira Ryman
Henry Lin

Frontiers in Neuroscience

143 views

Review

Published on 20 Nov 2025

Gut microbiota dysbiosis drives stroke-associated pneumonia: mechanisms and targeted therapeutic strategies

in Gut-Brain Axis

Jun Xiao
Jing Xia
Zhiying Chen
Weiwei Zha
Tian Xu
Xulong Chen
Xiaoping Yin

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1677744

647 views

Brief Research Report

Published on 18 Nov 2025

Tuberous sclerosis complex, epilepsy, and the microbiota-gut-brain axis: a pilot study of shared and divergent microbial signatures

in Gut-Brain Axis

Emerenziana Ottaviano
Matteo Domenico Marsiglia
Camilla Ceccarani
Silvia Ancona
Francesca Triva
Francesca La Briola
Stefania Bergamoni
Federica Teutonico
Alice Pompili
Ilaria Viganò

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1655456

671 views

Original Research

Published on 17 Nov 2025

Risk of occult gastrointestinal bleeding with increased gut Enterococcus and Staphylococcus for poor outcomes in ischemic stroke patients

in Gut-Brain Axis

Geng-Hong Xia
Wei Song
Jia-Hui Xie
Jing-Ru Liang
Jia Yin

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1624987

624 views

Editorial

Published on 17 Nov 2025

Editorial: Exploring gut neuroimmunology: focus on the enteric nervous system in health and disease

in Gut-Brain Axis

Matilde Otero-Losada
Sukhada Bhave
David Dora

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1726789

665 views

Perspective

Published on 13 Nov 2025

Acupuncture modulates the microbiota-gut-brain axis: a novel therapeutic strategy for amnestic mild cognitive impairment

in Gut-Brain Axis

Hang Xing
Wen-long Hu
Sheng-yong Bao

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1710066

871 views

Original Research

Published on 31 Oct 2025

Exploring gut microbiota alterations in Parkinson’s disease: insights from a 16S amplicon sequencing Eastern European pilot study

in Gut-Brain Axis

Ovidiu-Dumitru Ilie
Irina-Cezara Văcărean-Trandafir
Roxana-Maria Amărandi
Ilinca-Bianca Nita
Petru-Romeo Dobrin
Mara Doroftei
Iuliu-Cristian Ivanov
Gheorghe Savuta
Boris Kirov
Bogdan Doroftei

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1654995

1,308 views

Original Research

Published on 31 Oct 2025

Engineered spermidine-secreting Saccharomyces boulardii enhances olfactory memory in Drosophila melanogaster

in Gut-Brain Axis

Florance Parweez
Roger Palou
Ruizhen Li
Lanna Kadhim
Heath MacMillan
Mike Tyers
X. Johné Liu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1628160

2,062 views

Brief Research Report

Published on 01 Oct 2025

Exploring the relationship between GBA1 host genotype and gut microbiome in the GBA1L444P/WT mouse model: implications for Parkinson’s disease pathogenesis

in Gut-Brain Axis

Elisa Menozzi
Mallia Geiger
Victoria Meslier
Federico Fierli
Marine Gilles
Kai-Yin Chau
Aymeric David
Revi Shahar Golan
Alexandre Famechon
Sofia Koletsi

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1546203

2,266 views

Original Research

Published on 22 Sep 2025

Neuroprotective effects of bavachalcone in a mouse model of Parkinson’s disease: linking the gut-brain axis and systemic metabolism

in Gut-Brain Axis

Shuai Shi
Xiaohan Bian
Mengyun Li
Xiaobing Zhang
Wenji Huang
Xian Shao
Tiantian Lu
Xuebin Yu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1650288

3,926 views
1 citation

Editorial

Published on 03 Sep 2025

Editorial: Reviews in gut-brain axis: stress, dysregulation in gut-brain axis function and stress related disorders

in Gut-Brain Axis

Zuleide Maria Ignácio
Jonathan B. Clayton
Margarete Dulce Bagatini
Avinash Veerappa

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1665282

3,428 views

Original Research

Published on 02 Sep 2025

Neurofunctional correlates of emotional dysregulation in adolescent Crohn’s disease: a resting-state fMRI preliminary investigation

in Gut-Brain Axis

Ao Liu
Mengting Huang
Xiaoling Deng
Shuo Huang
Keshu Xu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1622708

3,309 views

Systematic Review

Published on 20 Aug 2025

Safety and efficacy of fecal microbiota transplantation in the treatment of Parkinson’s disease: a systematic review of clinical trials

in Gut-Brain Axis

Kewei Chen
Lirong Sun
Yilan Liu
Ran Chen

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1639911

3,740 views
1 citation

Original Research

Published on 13 Aug 2025

Altered gut microbial networks and metabolic pathways in multiple system atrophy: a comparative 16S rRNA study

in Gut-Brain Axis

Po-Chun Liu
Shao-Ying Cheng
Chih-Chi Li
Yu-Ke Wang
Yufeng Jane Tseng
Ming-Che Kuo

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1623165

2,514 views

Original Research

Published on 24 Jul 2025

Gut microbiota regulates innate anxiety through neural activity of medial prefrontal cortex in male mice

in Gut-Brain Axis

Jing Ren
Xiao-Ying Lian
Wan-Qian Ye
You-Lu Wen
Cheng-Lin Lu
Xiong Cao

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1599818

3,077 views