Frontiers in Oncology | Cancer Cell Signaling

Original Research

Published on 04 Sep 2025

Role of the ALK gene and PI3K/Akt/NF-κB signaling pathway in cervical cancer precancerous lesions

in Cancer Cell Signaling

Zhengran Sun
Ding Qi
Li Liu
Wenxia Ai
Buwei Han
Shimeng Wang
Mingge Liang
Yonggang Xia

Frontiers in Oncology

doi 10.3389/fonc.2025.1619703

1,201 views

Original Research

Published on 01 Sep 2025

Molecular mechanism of LncRNA MALAT1 in regulating hepatocellular carcinoma progression via the miR-383-5p/PRKAG1 axis and its role in the tumor immune microenvironment

in Cancer Cell Signaling

Rui Zhang
Mingze Li
Shan Lu
Anni Wang
Shujun Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1613596

625 views

Review

Published on 29 Aug 2025

Targeting the Wnt/β-catenin pathway and epithelial-mesenchymal transition in gastric cancer: mechanisms, therapeutic strategies, and clinical challenges

in Cancer Cell Signaling

Ruixin Shi
Zhenwen Cao
Jie Li
Ru Ji
Zhijuan Guo

Frontiers in Oncology

doi 10.3389/fonc.2025.1633699

687 views

Original Research

Accepted on 21 Aug 2025

A Systematic Review and Meta-analysis of the Effects of of Green Tea Extracts and Polyphenols in Female Hormone-Dependent Cancers for Benefit-Risk Evaluation

in Cancer Cell Signaling

Jin-jing He
Yan-fang Zhang
Ze-huang He
Zheng Lei

Frontiers in Oncology

doi 10.3389/fonc.2025.1579470

468 views

Review

Published on 05 Aug 2025

MicroRNAs in bone metastases: mechanisms and research progression

in Cancer Cell Signaling

Wei He
Zhen Wang
ZiHan Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1552902

1,088 views

Correction

Published on 17 Jul 2025

Correction: Food-derived compounds targeting ferroptosis for cancer therapy: from effects to mechanisms

in Cancer Cell Signaling

Jin-Wei Zhao
Wei-Yi Zhao
Zhongyang Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1644727

510 views

Correction

Accepted on 15 Jul 2025

Frontiers' correction template for authors

in Cancer Cell Signaling

Zhao Jinwei
Yu Zhongyang
Zhao Weiyi

Frontiers in Oncology

doi 10.3389/fonc.2025.1650268

454 views

Original Research

Published on 03 Jul 2025

FN1 from cancer-associated fibroblasts orchestrates pancreatic cancer metastasis via integrin-PI3K/AKT signaling

in Cancer Cell Signaling

Xianguang Zhu
Yanwei Li
Huifang Liu
Zheng Xiao

Frontiers in Oncology

doi 10.3389/fonc.2025.1595523

1,833 views

Review

Published on 19 Jun 2025

Hippo/YAP signaling pathway in colorectal cancer: regulatory mechanisms and potential drug exploration

in Cancer Cell Signaling

Lingqiu Zhang
Fan Zhang
Haimei Liang
Xiangling Qin
Yuemi Mo
Shiyi Chen
Jinling Xie
Xiaotao Hou
Jiagang Deng
Erwei Hao

Frontiers in Oncology

doi 10.3389/fonc.2025.1545952

2,825 views

Original Research

Published on 09 Jun 2025

Chimeric antigen receptor (CAR) -T cell therapy treatment Richter's transformation

in Cancer Cell Signaling

Shaomei Feng
Peihao Zheng
Haidi Liu
Meiling Sun
Yuelu Guo
Lixia Ma
Rui Liu
Zhonghua Fu
Fan Yang
Xiaoyan Ke

Frontiers in Oncology

doi 10.3389/fonc.2025.1591360

1,771 views

Review

Published on 09 Jun 2025

Food-derived compounds targeting ferroptosis for cancer therapy: from effects to mechanisms

in Cancer Cell Signaling

Jin-Wei Zhao
Wei-Yi Zhao
Zhongyang Yu

Frontiers in Oncology

doi 10.3389/fonc.2025.1568391

1,832 views

Original Research

Published on 29 May 2025

TFRC promotes the proliferation, migration, and invasion of osteosarcoma cells by increasing the intracellular iron content and RRM2 expression

in Cancer Cell Signaling

Guoqing Ren
Jian Zhou
Yong Su
Qiang Yang
Jianmin Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1567216

1,426 views

Review

Published on 22 Apr 2025

Regulation of PEST-containing nuclear proteins in cancer cells: implications for cancer biology and therapy

in Cancer Cell Signaling

Kai-Chun Jiang
Yong-Hao Zhu
Zhi-Liang Jiang
Yi Liu
Wahab Hussain
Huang-Yin Luo
Wei-Hang Sun
Xin-Ying Ji
Ding-Xi Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1548886

2,961 views

Review

Published on 03 Apr 2025

Cancer-associated fibroblasts: multidimensional players in liver cancer

in Cancer Cell Signaling

Yanyun Pan
Yuangang Qiu
Xinbin Zhou
Wei Mao
Xiaoming Xu

Frontiers in Oncology

doi 10.3389/fonc.2025.1454546

3,088 views
1 citation

Original Research

Published on 14 Mar 2025

OSMR induces M2 polarization of glioblastoma associated macrophages through JAK/STAT3 signaling pathway

in Cancer Cell Signaling

Changcheng Xiao
Liming Tan
Xiaofei Liu
Min Zhou
Ping Chen
Zhao Wang
Bing Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1538649

2,115 views
1 citation

Correction

Published on 22 Jan 2025

Corrigendum: Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models

in Cancer Cell Signaling

Andrea Mancini
Alessandro Colapietro
Loredana Cristiano
Alessandra Rossetti
Vincenzo Mattei
Giovanni Luca Gravina
Héctor Perez-Montoyo
Marc Yeste-Velasco
Jose Alfon
Carles Domenech

Frontiers in Oncology

doi 10.3389/fonc.2025.1538834

1,176 views