Frontiers in Oncology | Cancer Immunity and Immunotherapy

Original Research

Accepted on 16 Jul 2025

CD9 regulates proliferation, invasion, migration and radioresistance of esophageal squamous cell carcinoma by activating AKT/GSK3β signaling pathway

in Cancer Immunity and Immunotherapy

Liubing Hou
Zengyao Hao
Ge Zhang
Jiayuan Li
Yu Wang
Xiaoying Xue
Huandi Zhou

Frontiers in Oncology

doi 10.3389/fonc.2025.1625120

Original Research

Published on 16 Jul 2025

Lactylation-related gene signatures identify glioma molecular subtypes with prognostic, immunological, and therapeutic implications

in Cancer Immunity and Immunotherapy

Yanliang Tang
Xiaoli Zhang
Xiaofei Tang
Ye Yuan
Wenwen Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1613423

234 views

Mini Review

Published on 16 Jul 2025

Deciphering spatially confined immune evasion niches in osteosarcoma with 3-D spatial transcriptomics: a literature review

in Cancer Immunity and Immunotherapy

Guangqiang Qiu
Yongcheng Tang
Junhui Zuo
Heng Wu
Yongxian Wan

Frontiers in Oncology

doi 10.3389/fonc.2025.1640645

282 views

Study Protocol

Accepted on 15 Jul 2025

Total Neoadjuvant Chemoradiotherapy plus anti PD-1 for Mid-to-Low Locally Advanced Rectal Cancer: Study Protocol of a prospective, Single Arm, Phase Ⅱ Study (STARS -RC06)

in Cancer Immunity and Immunotherapy

Meichen Gu
Yuchen Guo
Liang He
Xuan Sun
Tingting Liang
Zhuo Wang
Ying Li
Zheng Liu
Jingyu Wang
Xiang Qiu

Frontiers in Oncology

doi 10.3389/fonc.2025.1594927

127 views

Study Protocol

Accepted on 11 Jul 2025

Trial in progress: Phase I study of non-viral gene-modified CAR-T cell therapy for malignant solid tumors expressing EPHB4 receptor (CARTiEr)

in Cancer Immunity and Immunotherapy

Chikako Funasaka
Yoichi Naito
Hitomi Kubota
Yukiko Ishiguro
Nozomu Fuse
Masashi Wakabayashi
Akihiro Sato
Junichiro Yuda
Genichiro Ishii
Toshihiro Suzuki

Frontiers in Oncology

doi 10.3389/fonc.2025.1633324

194 views

Opinion

Published on 11 Jul 2025

Oncolytic virus VG161 offers new hope for refractory liver cancer

in Cancer Immunity and Immunotherapy

Jinqiu Li
Haiyan Zhou
Xinping Wang
Kai Huang
Yanjun Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1605177

716 views

Mini Review

Published on 10 Jul 2025

Mapping the immunological landscape and emerging immunotherapeutic strategies in cervical cancer: a comprehensive review

in Cancer Immunity and Immunotherapy

Xinyi Zhang
Wenyang Nie
Wenwen Shao
Qian Guo

Frontiers in Oncology

doi 10.3389/fonc.2025.1620501

434 views

Original Research

Published on 09 Jul 2025

Association of visceral obesity indicators with prostate cancer: a cross-sectional study from Xinjiang

in Cancer Immunity and Immunotherapy

Zhiruo Cai
Xue Guan
Yunyun Xiao
Hengqing An
Ning Tao

Frontiers in Oncology

doi 10.3389/fonc.2025.1614743

409 views

Original Research

Accepted on 08 Jul 2025

Association between emotional distress and the efficacy of advanced gastric cancer patients undergoing treatment with immune checkpoint inhibitors: A cohort study and propensity score matching study

in Cancer Immunity and Immunotherapy

Ruoxi Tian
Siqi Wang
Zhengzheng Ji
Jiasong Li
Jingjing Zhang
Shasha Zhang
Zhanjun Guo

Frontiers in Oncology

doi 10.3389/fonc.2025.1516643

Review

Published on 08 Jul 2025

Shaping viral immunotherapy towards cancer-targeted immunological cell death

in Cancer Immunity and Immunotherapy

Anastasia S. Isaeva
Adriana D. Trujillo Yeriomenko
Esther Idota
Sofya I. Volodina
Natalia O. Porozova
Evgeny E. Bezsonov
Alexander S. Malogolovkin

Frontiers in Oncology

doi 10.3389/fonc.2025.1540397

616 views

Original Research

Published on 08 Jul 2025

Cytokine profiling identifies circulating IL-2, IL23 and sPD-L1 as prognostic biomarkers for treatment outcomes in non-small cell lung cancer patients undergoing anti-PD1 therapy

in Cancer Immunity and Immunotherapy

Kriti Jain
Anika Goel
Deepa Mehra
Deepak Kumar Rathore
Akshay Binayke
Shyam Aggarwal
Surajit Ganguly
Amit Awasthi
Evanka Madan
Nirmal Kumar Ganguly

Frontiers in Oncology

doi 10.3389/fonc.2025.1628379

291 views

Original Research

Accepted on 07 Jul 2025

Single-cell sequencing combined with machine learning to identify glioma biomarkers and therapeutic targets

in Cancer Immunity and Immunotherapy

Yu Yan
Zhengmin Chu
Qi Zhong
Genghuan Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1629102

157 views

Original Research

Accepted on 07 Jul 2025

Identification and Comprehensive Analysis of An Immune-Related Gene Prognostic Model for Indicating Tumor Immune Microenvironment Features in Soft Tissue Sarcoma

in Cancer Immunity and Immunotherapy

Shizhao Xu
Xuefeng Guan
Yuqiang Liu
Qian Cai
Jianzhi Sun

Frontiers in Oncology

doi 10.3389/fonc.2025.1609501

119 views

Original Research

Accepted on 30 Jun 2025

Performance of the neutrophil-to-lymphocyte ratio as a prognostic tool for survival in solid cancers

in Cancer Immunity and Immunotherapy

Irene Carrión-Barberà
Christian Lood

Frontiers in Oncology

doi 10.3389/fonc.2025.1616477

126 views

Original Research

Accepted on 30 Jun 2025

Multiplexed Immune Profiling and 3D Co-culture Assays to Assess the Individual Checkpoint Therapy Response in Head and Neck Squamous Cell Carcinoma

in Cancer Immunity and Immunotherapy

Verena Schweihofer
Daniela Schulz
Raquel Blazquez
Gero Brockhoff
Tobias Ettl
Mathias Fiedler
Sina Franziska Heimer
Julia Schikora
Richard Bauer
Anja Kathrin Wege

Frontiers in Oncology

doi 10.3389/fonc.2025.1622008

Systematic Review

Accepted on 24 Jun 2025

Systematic literature review of real-world evidence on overall survival in cancer patients before and after the approval of anti-PD-(L)1 therapy

in Cancer Immunity and Immunotherapy

Dweeti Nayak
Katherine Akers
Andrew Frederickson
Yves P.V. Mbous
Raquel Aguiar-Ibanez

Frontiers in Oncology

doi 10.3389/fonc.2025.1615795

164 views