Frontiers in Pain Research | Pain Mechanisms

Original Research

Published on 20 Nov 2025

Significant influence of low positive affect on pain: impact of COVID-19 on affect and daily chronic non-cancer pain trajectories in women

in Pain Mechanisms

Quinte T. Y. Kuper
Sophie F. Waardenburg
Lars Visseren
Ellen M. M. Jongen
Richel Lousberg
Therese A. M. J. van Amelsvoort
Andrea J. R. Balthasar

Frontiers in Pain Research

doi 10.3389/fpain.2025.1612328

255 views

Clinical Trial

Published on 13 Nov 2025

Impact of repeated exposure to CPM on CPM efficiency and pain sensitivity in healthy adults: a randomized controlled trial

in Pain Mechanisms

Priyanka Rana
Michael E. Robinson
Meryl J. Alappattu
Joseph Riley III
Donovan Lott
Mark D. Bishop

Frontiers in Pain Research

doi 10.3389/fpain.2025.1677563

433 views

Review

Published on 28 Oct 2025

Pain mechanism and management strategy of rheumatoid arthritis

in Pain Mechanisms

Dijun Wang
Ting Li
Weiqi Wang
Yonglan Ruan
Jiali Cai
Xiaojing Yan

Frontiers in Pain Research

doi 10.3389/fpain.2025.1693399

736 views

Mini Review

Published on 27 Oct 2025

Exploring fascia in myofascial pain syndrome: an integrative model of mechanisms

in Pain Mechanisms

Vlodeks Gromakovskis

Frontiers in Pain Research

doi 10.3389/fpain.2025.1712242

1,659 views

Case Report

Published on 14 Oct 2025

Case Report: A case of toothache of cardiac origin with a long-term clinical course

in Pain Mechanisms

Chizuko Maeda
Takayuki Suga
Kiyotoshi Oishi
Akira Toyofuku

Frontiers in Pain Research

doi 10.3389/fpain.2025.1625582

1,127 views

Original Research

Published on 13 Oct 2025

Acute postoperative pain trajectories and their impact on functional recovery following total knee arthroplasty

in Pain Mechanisms

Caijin Wen
Qin Qin
Lu Wei
Xi Luo
Jing Zhang

Frontiers in Pain Research

doi 10.3389/fpain.2025.1659917

954 views

Original Research

Published on 03 Oct 2025

Electroacupuncture therapy and bone cancer pain relief: experimental study on analgesic mechanisms in rats

in Pain Mechanisms

Yanhua Li
Fangfei Li
Caizhi Xiao
Jie Cao
Dongqin Xia
Yongzhong Wu

Frontiers in Pain Research

doi 10.3389/fpain.2025.1597472

852 views

Original Research

Published on 01 Oct 2025

Extreme pulse dosing of 10 kHz spinal cord stimulation: how low can you go?

in Pain Mechanisms

Mayank Gupta
Amy Reinert
C. O. West
Rose Province-Azalde
Kerry Bradley

Frontiers in Pain Research

doi 10.3389/fpain.2025.1633424

1,213 views

Brief Research Report

Published on 29 Aug 2025

Fear-learning is altered in a mouse neuropathic pain model

in Pain Mechanisms

Neda Assareh
Eddy E. Sokolaj
Saima Sadia
Kristen E. Anderson
Caitlin Frith
Olivia B. Walls
Vanessa A. Mitchell
Christopher W. Vaughan
Bryony L. Winters

Frontiers in Pain Research

doi 10.3389/fpain.2025.1648374

1,026 views

Original Research

Published on 21 Aug 2025

Wound infection and pain one month after trauma: an underestimated threat

in Pain Mechanisms

Kateryna Ksenchyna
Oleh Ksenchyn
Dmytro Dmytriiev
Oleksandr Nazarchuk

Frontiers in Pain Research

doi 10.3389/fpain.2025.1647785

1,107 views

Original Research

Published on 25 Jul 2025

Anti-nociceptive properties of cardiopulmonary baroreceptors in patients with chronic back pain

in Pain Mechanisms

Yuto Iwakuma
Jennifer Liu
Davina A. Clonch
Megan E. Gangwish
Christopher M. Lam
Seth W. Holwerda

Frontiers in Pain Research

doi 10.3389/fpain.2025.1593939

1,060 views

Review

Published on 03 Jul 2025

Gut microbiota-mediated pain sensitization: mechanisms and therapeutic implications

in Pain Mechanisms

Minghe Zhao
Ling Zhang
Zhihui Liu

Frontiers in Pain Research

doi 10.3389/fpain.2025.1626515

2,487 views

Original Research

Published on 20 Jun 2025

Disruptions in cortical circuit connectivity distinguish widespread hyperalgesia from localized pain

in Pain Mechanisms

George Kenefati
Mika M. Rockholt
Katherine Eisert
Qiaosheng Zhang
Deborah Ok
Christopher G. Gharibo
Lucia Daiana Voiculescu
Lisa V. Doan
Zhe Sage Chen
Jing Wang

Frontiers in Pain Research

doi 10.3389/fpain.2025.1548500

1,521 views
1 citation

Mini Review

Published on 13 May 2025

Redox reactions in chronic pain: mechanisms and relevance in fibromyalgia

in Pain Mechanisms

Tim Ho
Mark Ryan
Jonas Holle

Frontiers in Pain Research

doi 10.3389/fpain.2025.1593908

3,461 views
2 citations

Original Research

Published on 29 Apr 2025

Early post-trauma wound microbiota and its association with pain outcomes and mental health in combat-related extremity injuries: a prospective analysis

in Pain Mechanisms

Kateryna Ksenchyna
Dmytro Dmytriiev
Kostiantyn Volanskyi
Oleh Ksenchyn
Oleksandr Nazarchuk

Frontiers in Pain Research

doi 10.3389/fpain.2025.1564994

1,592 views
2 citations

Original Research

Published on 09 Apr 2025

An association between poor oral health, oral microbiota, and pain identified in New Zealand women with central sensitisation disorders: a prospective clinical study

in Pain Mechanisms

Sharon Erdrich
Ingrid C. Gelissen
Momchilo Vuyisich
Ryan Toma
Joanna E. Harnett

Frontiers in Pain Research

doi 10.3389/fpain.2025.1577193

10,183 views
2 citations