Frontiers in Pediatrics | Pediatric Immunology

Original Research

Published on 30 Jan 2026

Evaluation of the classification performance and cost-effectiveness of classification criteria in children with systemic lupus erythematosus

in Pediatric Immunology

Ana Luisa Rodríguez-Lozano
Alejandro Gabriel González-Garay
Miguel Ángel Villasis-Keever
Ruth G. Nájera-Velázquez
Marimar Sáez-de-Ocariz
Selma Cecilia Scheffler-Mendoza
Francisco Eduardo Rivas-Larrauri
Marco Antonio Yamazaki-Nakashimada
Silvestre García-De La Puente

Frontiers in Pediatrics

doi 10.3389/fped.2026.1745252

441 views

Case Report

Published on 30 Jan 2026

A case report of Behcet's disease in a child with trisomy 8 and literature review

in Pediatric Immunology

Kaixi Zhang
Chenxi Wei
Lijun Jiang
Xue Zhao
Qingxiao Su
Xingjie Qi
Hui Zhao
Zanhua Rong

Frontiers in Pediatrics

doi 10.3389/fped.2025.1750552

319 views

Review

Published on 29 Jan 2026

An etiopathogenesis of juvenile idiopathic arthritis: the protein-homeostasis-system hypothesis

in Pediatric Immunology

Kyung-Yil Lee
Jung-Woo Rhim

Frontiers in Pediatrics

doi 10.3389/fped.2026.1698713

671 views

Case Report

Accepted on 23 Jan 2026

Kawasaki disease versus MIS-C in a child with congenital coronary artery anomaly: a case report

in Pediatric Immunology

Oksana Boyarchuk
Marta-Viktoriia Zaleshchuk
Roksolana Zaremba
Oksana Chubata
Hanna Morkovkina

Frontiers in Pediatrics

654 views

Case Report

Published on 13 Jan 2026

Case Report: Organizing pneumonia associated with AQP4-antibody neuromyelitis optica spectrum disorder in children

in Pediatric Immunology

Lijun Zhang
Yixuan Liu
Yakun Wang
Liyuan Tian

Frontiers in Pediatrics

doi 10.3389/fped.2025.1729466

484 views

Original Research

Published on 12 Jan 2026

Incidence and severity of SARS-CoV-2 infection and vaccine BNT162 side effects in children and adolescents with Noonan Syndrome: a national multicentric study

in Pediatric Immunology

Sarah Dal Ben
Federica Tamburrino
Francesca Bonomo
Emanuela Scarano
Eleonora Orlandini
Gabriella Pozzobon
Claudia Giavoli
Chiara Corezzola
Maria Felicia Faienza
Giuseppa Patti

Frontiers in Pediatrics

doi 10.3389/fped.2025.1658340

636 views

Case Report

Published on 12 Dec 2025

STAT3 c.1915C > T variant-associated Hyper-IgE syndrome in a child: a case report

in Pediatric Immunology

Qianqian Dai
Yanan Wang
Zhiyuan Wang
Liang Ru

Frontiers in Pediatrics

doi 10.3389/fped.2025.1693297

962 views

Original Research

Published on 20 Nov 2025

Low lymphozyte pool, colon perforation and hydrocephalus as clinical features in an infant with a postzygotic PIK3CA variant

in Pediatric Immunology

Ximena Léon-Lara
Sarina Ravens
Sandra von Hardenberg
Bernd Auber
Anke K. Bergmann
Laura Ospina
Florian Guthmann
Christiane Wübbena
Jan Brechler
Jürgen Weidemann

Frontiers in Pediatrics

doi 10.3389/fped.2025.1650077

883 views

Review

Published on 17 Oct 2025

Atopic dermatitis, primary atopic disorders, and the cutaneous microbiome: current understanding of an expanding field

in Pediatric Immunology

Amir Abidov
Diana K. Bayer

Frontiers in Pediatrics

doi 10.3389/fped.2025.1670623

2,273 views

Case Report

Published on 15 Oct 2025

Case Report: Nystagmus as a core presenting sign in pediatric anti-Ma2 antibody-associated cerebellar ataxia: diagnostic implications from clinical and serological profiling

in Pediatric Immunology

Jiehui Ma
Yuting Yang
Zhiyu Li
Qianqian Tan
Pan Cao
Kun Ni
Xiaofang Cai
Dan Sun

Frontiers in Pediatrics

doi 10.3389/fped.2025.1659483

1,593 views

Original Research

Published on 10 Oct 2025

Subclinical ocular surface changes in children with newly diagnosed allergy

in Pediatric Immunology

Ata Baytaroğlu
Mesut Saka

Frontiers in Pediatrics

doi 10.3389/fped.2025.1648267

1,824 views

Editorial

Published on 25 Sep 2025

Editorial: Challenges and advances in primary antibody deficiencies diagnosis, treatment and follow-up

in Pediatric Immunology

Adriano La Vecchia
Lucia Augusta Baselli
Carlo Agostoni
Rosa Maria Dellepiane

Frontiers in Pediatrics

doi 10.3389/fped.2025.1702168

2,047 views

Original Research

Published on 11 Sep 2025

Comparison of the vitamin D level between children with and without cow's milk protein allergy: a systematic review with meta-analysis

in Pediatric Immunology

Xueming Zheng
Yi Jin
Jianhong Luo
Fan Jiang
Limin Zhang
Xiaoxue Wang
Hui Zhang
Shaofei Ma
Yejuan Li

Frontiers in Pediatrics

doi 10.3389/fped.2025.1649825

2,679 views
1 citation

Original Research

Published on 28 Aug 2025

Laboratory diagnosis of 44 cases of pediatric histiocytic necrotizing lymphadenitis

in Pediatric Immunology

Jingjing Jin
Songjian Lu
Honghua Lin

Frontiers in Pediatrics

doi 10.3389/fped.2025.1638239

2,667 views

Case Report

Published on 14 Aug 2025

Case Report: Hemophagocytic lymphohistiocytosis associated with NBAS gene variant and Epstein-Barr virus (EBV) infection

in Pediatric Immunology

Jing Zhao
Xilong Chen
Shixia Yue

Frontiers in Pediatrics

doi 10.3389/fped.2025.1635534

2,229 views

Case Report

Published on 04 Aug 2025

Case Report: From IgA nephropathy to pneumonia, periappendiceal abscess, pulmonary arterial hypertension, and basal ganglia calcification: a case of chronic active Epstein-Barr infection in a child

in Pediatric Immunology

Shuying Fan
Xin Wang
Ning Wei
Qiumei Zhou
Wenhong Wang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1589151

2,724 views

Original Research

Published on 01 Aug 2025

The diagnostic value of lymphocyte profiling for infectious mononucleosis and mycoplasma pneumoniae pneumonia

in Pediatric Immunology

Xuan Shen
Wenya Li
Jijin Qi
Qing Zhong
Yaoyun Zhang
Tianyu Sun
Siqi Shi
Liang Zhang
Jing Su

Frontiers in Pediatrics

doi 10.3389/fped.2025.1607857

2,039 views

Case Report

Published on 31 Jul 2025

Case Report: Exploring the spectrum of A20 haploinsufficiency in children

in Pediatric Immunology

Sahana Jayaraman
Nayimisha Balmuri

Frontiers in Pediatrics

doi 10.3389/fped.2025.1624715

2,307 views
1 citation

Case Report

Published on 18 Jul 2025

Case Report: Clinical, molecular, and functional characterization of autoimmune lymphoproliferative syndrome—a family study with a multimodal diagnosis

in Pediatric Immunology

Bruna Cândido Guido
Ricardo Camargo
Caroliny Victoria dos Santos Silva
Anna Carolina Silva Dias
Robéria Mendonça de Pontes
Agenor de Castro Moreira dos Santos Júnior
Raquel Alves Toscano
Fabíola Scancetti Tavares
Alexandre de Albuquerque Antunes
Karina Mescouto de Melo

Frontiers in Pediatrics

doi 10.3389/fped.2025.1639749

2,310 views

Case Report

Published on 09 Jul 2025

Successful anti-IL-6 treatment for interstitial lung disease associated with STAT3 gain-of-function: a case report and literature review

in Pediatric Immunology

Peng Zhou
Meifang Zhu
Yuting Pan
Jing Jin
Zhidan Fan
Haiguo Yu

Frontiers in Pediatrics

doi 10.3389/fped.2025.1577746

1,860 views
1 citation

Case Report

Published on 02 Jul 2025

Case Report: Intra-articular injection of tocilizumab for arthritis treatment in chronic graft-vs.-host disease

in Pediatric Immunology

Mingyu Xie
Qin Liu
Huiting Yuan
Yumei Chen
Xian Zou
Zhenhong Zhang
Baimao Zhong
Huasong Zeng
Haisheng Zeng

Frontiers in Pediatrics

doi 10.3389/fped.2025.1515706

2,875 views
1 citation

Case Report

Published on 27 Jun 2025

Infantile epileptic spasms syndrome as a new phenotype in TOP2B deficiency caused by a de novo variant: a case report and literature review

in Pediatric Immunology

Guo-qin Zhu
Yao Yao
Ling-yun Yang
Ying Hua
Guo-min Li

Frontiers in Pediatrics

doi 10.3389/fped.2025.1542268

1,955 views
1 citation

Brief Research Report

Published on 19 Jun 2025

Rethinking phenylalanine levels in phenylketonuria for optimal neurocognitive development beyond childhood

in Pediatric Immunology

Beatriz Câmara
Cristina Florindo
Cláudia Bandeira de Lima
Nélia Correia
Inês Fernandes
Manuela Batista
Ana Gaspar
Patrícia Janeiro

Frontiers in Pediatrics

doi 10.3389/fped.2025.1488809

2,854 views

Review

Published on 19 Jun 2025

Research progress on microecology and childhood respiratory infections via the lung-gut axis

in Pediatric Immunology

Zhixuan He
Zixuan Wang
Jiao Yin
Qiang Wang

Frontiers in Pediatrics

doi 10.3389/fped.2025.1509333

2,477 views

553 articles

articles

Evaluation of the classification performance and cost-effectiveness of classification criteria in children with systemic lupus erythematosus

A case report of Behcet's disease in a child with trisomy 8 and literature review

An etiopathogenesis of juvenile idiopathic arthritis: the protein-homeostasis-system hypothesis

Kawasaki disease versus MIS-C in a child with congenital coronary artery anomaly: a case report

Case Report: Organizing pneumonia associated with AQP4-antibody neuromyelitis optica spectrum disorder in children

Incidence and severity of SARS-CoV-2 infection and vaccine BNT162 side effects in children and adolescents with Noonan Syndrome: a national multicentric study

STAT3 c.1915C > T variant-associated Hyper-IgE syndrome in a child: a case report

Low lymphozyte pool, colon perforation and hydrocephalus as clinical features in an infant with a postzygotic PIK3CA variant

Atopic dermatitis, primary atopic disorders, and the cutaneous microbiome: current understanding of an expanding field

Case Report: Nystagmus as a core presenting sign in pediatric anti-Ma2 antibody-associated cerebellar ataxia: diagnostic implications from clinical and serological profiling

Subclinical ocular surface changes in children with newly diagnosed allergy

Editorial: Challenges and advances in primary antibody deficiencies diagnosis, treatment and follow-up

Comparison of the vitamin D level between children with and without cow's milk protein allergy: a systematic review with meta-analysis

Laboratory diagnosis of 44 cases of pediatric histiocytic necrotizing lymphadenitis

Case Report: Hemophagocytic lymphohistiocytosis associated with NBAS gene variant and Epstein-Barr virus (EBV) infection

Case Report: From IgA nephropathy to pneumonia, periappendiceal abscess, pulmonary arterial hypertension, and basal ganglia calcification: a case of chronic active Epstein-Barr infection in a child

The diagnostic value of lymphocyte profiling for infectious mononucleosis and mycoplasma pneumoniae pneumonia

Case Report: Exploring the spectrum of A20 haploinsufficiency in children

Case Report: Clinical, molecular, and functional characterization of autoimmune lymphoproliferative syndrome—a family study with a multimodal diagnosis

Successful anti-IL-6 treatment for interstitial lung disease associated with STAT3 gain-of-function: a case report and literature review

Case Report: Intra-articular injection of tocilizumab for arthritis treatment in chronic graft-vs.-host disease

Infantile epileptic spasms syndrome as a new phenotype in TOP2B deficiency caused by a de novo variant: a case report and literature review

Rethinking phenylalanine levels in phenylketonuria for optimal neurocognitive development beyond childhood

Research progress on microecology and childhood respiratory infections via the lung-gut axis