Frontiers in Toxicology

Original Research

Published on 23 Jun 2025

An injectable 2.5% cross-linked polyacrylamide hydrogel (2.5 iPAAG) demonstrates no neurotoxicity in human induced pluripotent stem cells-derived iCell® GlutaNeurons

Peter S. Walmod
Philip Kusk
Nina Jøhnk
Ieva Ankorina-Stark
Anthony Essex

Frontiers in Toxicology

doi 10.3389/ftox.2025.1585430

898 views

Original Research

Accepted on 20 Jun 2025

Assessment of a Heated Herbal Product's Tobacco Harm Reduction Potential: Pre-Clinical and Clinical Studies

Álvaro Marinas-Lacasta
Ian M Fearon
Matthew Stevenson
Tasnim Abusalem
Fiona Chapman
Edgar Trelles-Sticken
Roman Wieczorek
Sarah Jean Pour
Ole Dethloff
Ourania Komini

Frontiers in Toxicology

doi 10.3389/ftox.2025.1589480

250 views

Original Research

Accepted on 18 Jun 2025

Refinement of a Workflow for Human Relevance Assessment of Adverse Outcome Pathways and Associated New Approach Methodologies

Annick D. van den Brand
Julia J. Meerman
Christina H.J. Veltman
Mirjam Luijten

Frontiers in Toxicology

doi 10.3389/ftox.2025.1616817

234 views

Review

Accepted on 12 Jun 2025

Fetal bovine serum: How to leave it behind in the pursuit of more reliable science

Tilo Weber
Atena Malakpour Permlid
Aline Chary
Vito D'Alessandro
Leah Haut
Sebastian Seufert
Esther Veronika Wenzel
James Hickman
Karen Bieback
Joachim Wiest

Frontiers in Toxicology

doi 10.3389/ftox.2025.1612903

509 views

Original Research

Published on 12 Jun 2025

Bioengineering of novel organotypic 3D human liver tissue model for drug-induced liver injury and toxicity studies

Camden Holm
Joseph Finelli
Mateo Frare
Alex Armento
Seyoum Ayehunie

Frontiers in Toxicology

doi 10.3389/ftox.2025.1574387

1,296 views

Review

Published on 09 Jun 2025

Cannabis concentrate vaping chemistry

Kaelas R. Munger
Killian M. Anreise
Robert M. Strongin

Frontiers in Toxicology

doi 10.3389/ftox.2025.1568207

1,873 views

Original Research

Published on 06 Jun 2025

The patterns of dynamic changes in blood toxicant levels, prognosis, and regression in a case of occupational chlorfenapyr exposure

Jianjian Liu
Zhaozhao Shan
Chen Wang
Xiangdong Jian
Baotian Kan
Yingli Ren

Frontiers in Toxicology

doi 10.3389/ftox.2025.1570887

1,033 views

Original Research

Published on 04 Jun 2025

Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern values

Taylor Builee
Todd A. Kennedy
Valériane Levelut
Megan A. Hahn
Stephen Bond
Michael K. Peterson
Frances K. Hsia
Alessia Stornetta
Kristin J. Erickson
Kimberly D. Ehman

Frontiers in Toxicology

doi 10.3389/ftox.2025.1600127

3,371 views

Systematic Review

Published on 30 May 2025

A systematic review of the effects of nanoplastics on fish

Asok K. Dasmahapatra
Joydeep Chatterjee
Paul B. Tchounwou

Frontiers in Toxicology

doi 10.3389/ftox.2025.1530209

2,008 views

Original Research

Published on 27 May 2025

Repetitive ozone exposure worsens features of muco-inflammatory disease in developed Scnn1b-Tg+ mice lungs

Thao Vo
Sonika Patial
Yogesh Saini

Frontiers in Toxicology

doi 10.3389/ftox.2025.1540468

961 views

Perspective

Accepted on 26 May 2025

Stress Convulsions in Rodents: Translational Relevance Within a Weight-of-Evidence Framework for Human Seizure Risk

Monica Metea
Joseph J DeGeorge

Frontiers in Toxicology

doi 10.3389/ftox.2025.1600816

252 views

Original Research

Published on 26 May 2025

Immunotoxicity assessment of multiwalled carbon nanotubes following whole-body inhalation exposure for 30 and 90 days in B6C3F1/N mice and 30 days in HSD:Harlan Sprague Dawley SD® rats

Victor J. Johnson
Nigel J. Walker
Michael I. Luster
Gary R. Burleson
Michelle Cora
Gregory L. Baker
Barney Sparrow
Dori R. Germolec

Frontiers in Toxicology

doi 10.3389/ftox.2025.1539810

915 views

Original Research

Published on 21 May 2025

Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina

Florencia Doná
Virginia Lorenz
Georgina Stegmayer
Tamara Ricardo
Stefanía D’Iorio
Fernando Ponzo
María Rosa Repetti
Luisina Delma Demonte
María Mercedes Milesi
Jorgelina Varayoud

Frontiers in Toxicology

doi 10.3389/ftox.2025.1579952

1,536 views

Editorial

Published on 15 May 2025

Editorial: Legacy & emerging contaminants in the aquatic environment—bridging knowledge, policy, and future

Abdul Qadeer
Mengyang Liu
Sanjeeb Mohapatra
Racliffe Weng Seng Lai

Frontiers in Toxicology

doi 10.3389/ftox.2025.1611852

1,091 views

Original Research

Published on 15 May 2025

Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based in vitro assessment with repeated exposure to whole cigarette smoke

Sakuya Ichikawa
Shugo Muratani
Keigo Sano
Kazuo Erami
Akina Mori
Risa Matsumoto
Shigeaki Ito

Frontiers in Toxicology

doi 10.3389/ftox.2025.1564857

1,104 views

Original Research

Published on 15 May 2025

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation

Shigeaki Ito
Sakuya Ichikawa
Risa Matsumoto
Shugo Muratani
Keigo Sano
Akina Mori
Kazuo Erami

Frontiers in Toxicology

doi 10.3389/ftox.2025.1564864

919 views

527 Publications

Volume 7 - 2025

An injectable 2.5% cross-linked polyacrylamide hydrogel (2.5 iPAAG) demonstrates no neurotoxicity in human induced pluripotent stem cells-derived iCell® GlutaNeurons

Assessment of a Heated Herbal Product's Tobacco Harm Reduction Potential: Pre-Clinical and Clinical Studies

Refinement of a Workflow for Human Relevance Assessment of Adverse Outcome Pathways and Associated New Approach Methodologies

Fetal bovine serum: How to leave it behind in the pursuit of more reliable science

Bioengineering of novel organotypic 3D human liver tissue model for drug-induced liver injury and toxicity studies

Cannabis concentrate vaping chemistry

The patterns of dynamic changes in blood toxicant levels, prognosis, and regression in a case of occupational chlorfenapyr exposure

Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern values

A systematic review of the effects of nanoplastics on fish

Repetitive ozone exposure worsens features of muco-inflammatory disease in developed Scnn1b-Tg+ mice lungs

Stress Convulsions in Rodents: Translational Relevance Within a Weight-of-Evidence Framework for Human Seizure Risk

Immunotoxicity assessment of multiwalled carbon nanotubes following whole-body inhalation exposure for 30 and 90 days in B6C3F1/N mice and 30 days in HSD:Harlan Sprague Dawley SD® rats

Residential proximity to agricultural fields, urinary glyphosate levels and breast cancer risk: a case-control study in Argentina

Editorial: Legacy & emerging contaminants in the aquatic environment—bridging knowledge, policy, and future

Quantitative adverse outcome pathway modeling for cigarette-smoke-induced airway mucus hypersecretion. Part 1: adverse-outcome-pathway-based in vitro assessment with repeated exposure to whole cigarette smoke

Quantitative adverse outcome pathway modeling for cigarette smoke-inducible airway mucus hypersecretion. Part 2: Bayesian network modeling for probabilistic risk estimation