Original Research ARTICLE
ARMOUR - a rice miRNA: mRNA interaction resource
- 1International Centre for Genetic Engineering and Biotechnology, India
- 2Bionivid Technology Pvt. Ltd., India
ARMOUR was developed as A Rice miRNA:mRNA interaction resource. This informative and interactive database includes the experimentally validated expression profiles of miRNAs under different developmental and abiotic stress conditions across 7 Indian rice cultivars. This comprehensive database covers 689 known and 1664 predicted novel miRNAs and their expression profiles in more than 38 different tissues or conditions along with their predicted/known target transcripts. The understanding of miRNA:mRNA interactome in regulation of functional cellular machinery is supported by the sequence information of the mature and hairpin structures. ARMOUR provides flexibility to users in querying the database using multiple ways like known gene identifiers, gene ontology identifiers, KEGG identifiers and also allows on the fly fold change analysis and sequence search query with inbuilt BLAST algorithm. ARMOUR database provides a cohesive platform for novel and mature miRNAs and their expression in different experimental conditions and allows searching for their interacting mRNA targets, GO annotation and their involvement in various biological pathways. The ARMOUR database includes a provision for adding more experimental data from users, with an aim to develop it as a platform for sharing and comparing experimental data contributed by research groups working on rice.
Keywords: miRNA, database, target, gene annotation, Pathway, Expression
Received: 12 Oct 2017;
Accepted: 16 Apr 2018.
Edited by:Marco Pellegrini, Consiglio Nazionale Delle Ricerche (CNR), Italy
Reviewed by:Shrikant S. Mantri, National Agri-Food Biotechnology Institute, India
Patricia Baldrich, Donald Danforth Plant Science Center, United States
Copyright: © 2018 Sanan-Mishra, Tripathi, Goswami, Shukla, Vasudevan and Goswami. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Dr. Neeti Sanan-Mishra, International Centre for Genetic Engineering and Biotechnology, New Delhi, India, email@example.com