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Front. Plant Sci. | doi: 10.3389/fpls.2018.01674

Cellular complexity in MAPK signaling in plants: questions and emerging tools to answer them

  • 1Bâtiment 630, Plateau du Moulon, Université Paris-Saclay, France
  • 2University of Wisconsin-Madison, United States

Mitogen Activated Protein kinase (MAPK) cascades play an important role in many aspects of plant growth, development, and environmental response. Because of their central role in many important processes, MAPKs have been extensively studied using biochemical and genetic approaches. This work has allowed for the description of which particular MAPK genes and proteins are involved in a number of different signaling pathways. Less well developed, however, is our understanding of how MAPK cascades and their corresponding signaling pathways are organized at subcellular levels. In this review, we will provide an overview of plant MAPK signaling, including a discussion of what is known about cellular mechanisms for achieving signaling specificity. Then we will explore what is currently known about the subcellular localization of MAPK proteins in resting conditions and after pathway activation. Finally, we will discuss a number of new experimental methods that have not been widely deployed in plants that have the potential to provide a deeper understanding of the spatial and temporal dynamics of MAPK signaling.

Keywords: signaling cascade, MAPK, Phosphorylation, plant, Microscopy, Activity sensors

Received: 05 Jul 2018; Accepted: 26 Oct 2018.

Edited by:

Stéphane Bourque, Université de Bourgogne, France

Reviewed by:

Kenichi Tsuda, Max Planck Institut für Pflanzenzüchtungsforschung, Germany
Andrea Pitzschke, Division of Plant Physiology, Department of Cell Biology & Physiology, University of Salzburg, Austria  

Copyright: © 2018 Colcombet and Krysan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Jean Colcombet, Université Paris-Saclay, Bâtiment 630, Plateau du Moulon, Gif-sur-Yvette, Île-de-France, France,