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Review ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Plant Sci. | doi: 10.3389/fpls.2019.01022

Glycosylphosphatidylinositol-anchored proteins in Arabidopsis and one of their common roles in signaling transduction

  • 1Fujian Agriculture and Forestry University, China

Diverse proteins are found modified with glycosylphosphatidylinositol (GPI) at their carboxyl-terminus (C-terminus) in eukaryotes, which allows them to associate with membrane lipid bilayers and anchored on the external surface of plasma membrane. GPI-anchored proteins (GPI-APs) play crucial roles in various processes, and more and more GPI-APs have been identified and studied. In this review, the previous genomic and proteomic predictions of GPI-APs in Arabidopsis have been updated, which reveals their high abundance and complexity. From studies of individual GPI-APs in Arabidopsis, certain GPI-APs have been found associated with partner receptor like kinases (RLKs), targeting RLKs to their subcellular localization, and helping to recognize extracellular signaling polypeptide ligands. Interestingly, the association might also be involved in ligand selection. The analyses suggest that GPI-APs are essential and widely involved in signal transduction through association with RLKs.

Keywords: GPI (glycosylphosphatidylinositol), signaling / signaling pathways, RLK, Receptor-like kinase, Ligand, GPI-anchored protein (GPI-AP)

Received: 06 May 2019; Accepted: 22 Jul 2019.

Edited by:

Els J. VAN DAMME, Ghent University, Belgium

Reviewed by:

Hiroyasu Motose, Okayama University, Japan
Daisuke Takahashi, Max Planck Institute of Molecular Plant Physiology, Germany  

Copyright: © 2019 Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Ke Zhou, Fujian Agriculture and Forestry University, Fuzhou, 350002, Fujian Province, China, zhouke0525@gmail.com