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Front. Plant Sci. | doi: 10.3389/fpls.2019.01122

Dealing with stress: A review of plant SUMO proteases

 Ari Sadanandom1* and Rebecca Morrell1
  • 1Durham University, United Kingdom

The SUMO system is a rapid dynamic post-translational mechanism employed by eukaryotic cells to respond to stress. Plant cells experience hyperSUMOylation of substrates in response to stresses such as heat, ethanol and drought. Many SUMOylated proteins are located in the nucleus, SUMOylation altering many nuclear processes. The SUMO proteases, play two key functions in the SUMO cycle by generating free SUMO they have an important role in regulating the SUMO cycle and by cleaving SUMO off SUMOylated proteins they provide specificity to which proteins become SUMOylated. This review summarises the broad literature of plant SUMO proteases describing their catalytic activity, domains and structure, evolution, localisation, response to stress and highlighting potential new areas of research in the future.

Keywords: SUMO protease, SUMO cycle, stress, Protein modification, Ubiquitin

Received: 03 Jun 2019; Accepted: 14 Aug 2019.

Copyright: © 2019 Sadanandom and Morrell. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Prof. Ari Sadanandom, Durham University, Durham, United Kingdom, ari.sadanandom@durham.ac.uk